Abstract
Microbial lipids have recently attracted attention as an intriguing alternative for the biodiesel and oleochemical industries to achieve sustainable energy generation. However, large-scale lipid production remains limited due to the high processing costs. As multiple variables affect lipid synthesis, an up-to-date overview that will benefit researchers studying microbial lipids is necessary. In this review, the most studied keywords from bibliometric studies are first reviewed. Based on the results, the hot topics in the field were identified to be associated with microbiology studies that aim to enhance lipid synthesis and reduce production costs, focusing on the biological and metabolic engineering involved. The research updates and tendencies of microbial lipids were then analyzed in depth. In particular, feedstock and associated microbes, as well as feedstock and corresponding products, were analyzed in detail. Strategies for lipid biomass enhancement were also discussed, including feedstock adoption, value-added product synthesis, selection of oleaginous microbes, cultivation mode optimization, and metabolic engineering strategies. Finally, the environmental implications of microbial lipid production and possible research directions were presented.
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This work was supported by Tianjin Education Commission Scientific Research Planning Project [grant number 2021KJ064] and Guangdong Basic and Applied Basic Research Foundation [grant number 2022A1515110943].
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All authors contributed to the study’s conception and design. Material preparation, data collection, and analysis were performed by Haishu Sun, Zhen Gao, and Lirong Zhang. Review and editing were performed by Xiaona Wang, Ming Gao, and Qunhui Wang. Supervision was performed by Xiaona Wang and Qunhui Wang. The first draft of the manuscript was written by Haishu Sun, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.
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Sun, H., Gao, Z., Zhang, L. et al. A comprehensive review on microbial lipid production from wastes: research updates and tendencies. Environ Sci Pollut Res 30, 79654–79675 (2023). https://doi.org/10.1007/s11356-023-28123-6
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DOI: https://doi.org/10.1007/s11356-023-28123-6