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UV-driven removal of tricyclic antidepressive drug amitriptyline using TiO2 and TiO2/WO3 coatings

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Abstract

Photocatalytic degradations of tricyclic antidepressive amitriptyline (AMI) in aqueous solutions under UV irradiation were performed using TiO2 and TiO2/WO3 coatings, as photocatalysts. Coatings were formed on a pure titanium substrate using plasma electrolytic oxidation (PEO). The effects of chosen synthesis parameters on structural properties of prepared coatings have been investigated using micro-Raman spectroscopy and non-contact atomic force microscopy. Raman scattering measurements showed that coatings contain different amounts of crystalline anatase TiO2 and monoclinic WO3−x phases, as well as amorphous and/or disordered phases of both oxides. Also, results indicated that coatings’ surface become more disordered and inhomogeneous with increasing duration of the PEO. The coating T/W(45 s) prepared during 45 s of PEO has shown the highest efficiency in the UV-driven removal of AMI. T/W(45 s) showed slightly decrease in photodegradation efficiency after four successive runs. The results showed that the degradation of AMI led to the formation of ionic by-products (nitrite, nitrate, ammonium ion, acetate, and formate), whereas degree of mineralization was the highest (38.8%) using coating T/W(45 s) after 120 min of irradiation. Also, there was no significant toxicity observed after irradiation of AMI solutions using different coatings on four mammalian cell lines: rat hepatoma, mouse neuroblastoma, human colon adenocarcinoma, and human fetal lung.

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Acknowledgements

Authors acknowledge financial support of the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant No. 451-03-68/2020-14/200125 and III45018). Also, the authors would like to thank Dr. Marko Radović for the AFM measurements of some investigated coatings.

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Authors and Affiliations

  1. Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Trg D. Obradovića 3, 21000, Novi Sad, Serbia

    Nina L. Finčur, Snežana P. Maletić & Biljana F. Abramović

  2. Center for Solid State Physics and New Materials, Institute of Physics, University of Belgrade, Pregrevica 118, 11080, Belgrade, Serbia

    Mirjana Grujić-Brojčin & Maja J. Šćepanović

  3. Oncology Institute of Vojvodina, Dr Goldmana 4, 21204, Sremska Kamenica, Serbia

    Dragana D. Četojević-Simin

  4. Faculty of Physics, University of Belgrade, Studentski Trg 12-16, 11000, Belgrade, Serbia

    Stevan Stojadinović

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  1. Nina L. Finčur
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Correspondence to Nina L. Finčur.

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Finčur, N.L., Grujić-Brojčin, M., Šćepanović, M.J. et al. UV-driven removal of tricyclic antidepressive drug amitriptyline using TiO2 and TiO2/WO3 coatings. Reac Kinet Mech Cat 132, 1193–1209 (2021). https://doi.org/10.1007/s11144-021-01936-7

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