1. PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model

   • Ching-Chi Chiu
   • Chin-Song Lu
   • Hung-Li Wang

   OriginalPaper 08 August 2018 Pages: 3835 - 3853

   

2. Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain

   • P. A. Shantanu
   • Dilip Sharma
   • Vinod Tiwari

   ReviewPaper 13 September 2018 Pages: 3854 - 3864

   

3. Molecular Association of Glia Maturation Factor with the Autophagic Machinery in Rat Dopaminergic Neurons: a Role for Endoplasmic Reticulum Stress and MAPK Activation

   • Govindhasamy Pushpavathi Selvakumar
   • Shankar S Iyer
   • Asgar Zaheer

   OriginalPaper 14 September 2018 Pages: 3865 - 3881

   

4. Choline Rescues Behavioural Deficits in a Mouse Model of Rett Syndrome by Modulating Neuronal Plasticity

   • Eunice W. M. Chin
   • Wee Meng Lim
   • Eyleen L. K. Goh

   OriginalPaper Open access 15 September 2018 Pages: 3882 - 3896

   

5. Sprouty2—a Novel Therapeutic Target in the Nervous System?

   • Barbara Hausott
   • Lars Klimaschewski

   ReviewPaper Open access 17 September 2018 Pages: 3897 - 3903

   

6. Fragile X and APP: a Decade in Review, a Vision for the Future

   • Cara J. Westmark

   ReviewPaper 17 September 2018 Pages: 3904 - 3921

   

7. Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics

   • Maria Filipe Ribeiro
   • Tânia Genebra
   • Susana Solá

   OriginalPaper 18 September 2018 Pages: 3922 - 3936

   

8. Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury

   • M. Lanza
   • M. Campolo
   • Emanuela Esposito

   OriginalPaper 18 September 2018 Pages: 3937 - 3947

   

9. Diltiazem Promotes Regenerative Axon Growth

   • Eric A. Huebner
   • Stéphane Budel
   • Clifford J. Woolf

   OriginalPaper 19 September 2018 Pages: 3948 - 3957

   

10. Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain

    • J. London
    • F. K. Ndiaye
    • C. Rouch

    OriginalPaper 20 September 2018 Pages: 3958 - 3971

    

11. Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation

    • Kuo-Hsuan Chang
    • Guey-Jen Lee-Chen
    • Chiung-Mei Chen

    OriginalPaper Open access 20 September 2018 Pages: 3972 - 3983

    

12. Visualization of the Breakdown of the Axonal Transport Machinery: a Comparative Ultrastructural and Immunohistochemical Approach

    • Sebastian Rühling
    • Franziska Kramer
    • Tanja Hochstrasser

    OriginalPaper 21 September 2018 Pages: 3984 - 3998

    

13. Myelin Water Fraction Imaging Reveals Hemispheric Asymmetries in Human White Matter That Are Associated with Genetic Variation in PLP1

    • Sebastian Ocklenburg
    • Catrona Anderson
    • Erhan Genç

    OriginalPaper 21 September 2018 Pages: 3999 - 4012

    

14. The Expression and Cellular Localisation of Neurotrophin and Neural Guidance Molecules in Peritoneal Ectopic Lesions

    • Razan Asally
    • Robert Markham
    • Frank Manconi

    OriginalPaper 25 September 2018 Pages: 4013 - 4022

    

15. Aβ42 Peptide Promotes Proliferation and Gliogenesis in Human Neural Stem Cells

    • A. Bernabeu-Zornoza
    • R. Coronel
    • Isabel Liste

    OriginalPaper 27 September 2018 Pages: 4023 - 4036

    

16. Genetic Knockdown of mGluR5 in Striatal D1R-Containing Neurons Attenuates l-DOPA-Induced Dyskinesia in Aphakia Mice

    • José-Rubén García-Montes
    • Oscar Solís
    • Rosario Moratalla

    OriginalPaper 27 September 2018 Pages: 4037 - 4050

    

17. Intragenic Transcriptional cis-Antagonism Across SLC6A3

    • Ying Zhao
    • Jinlong Yu
    • Zhicheng Lin

    OriginalPaper 27 September 2018 Pages: 4051 - 4060

    

18. Chronic Testosterone Increases Impulsivity and Influences the Transcriptional Activity of the Alpha-2A Adrenergic Receptor Signaling Pathway in Rat Brain

    • Juhee Agrawal
    • Birgit Ludwig
    • Yogesh Dwivedi

    OriginalPaper 27 September 2018 Pages: 4061 - 4071

    

19. Upregulation of MicroRNA miR-9 Is Associated with Microcephaly and Zika Virus Infection in Mice

    • Haijun Zhang
    • Yafei Chang
    • Tao Sun

    OriginalPaper 27 September 2018 Pages: 4072 - 4085

    

20. AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress

    • Houssni Abid
    • Dorthe Cartier
    • Isabelle Lihrmann

    OriginalPaper 28 September 2018 Pages: 4086 - 4101

    

21. Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells

    • Sandhya Prakash Kamath
    • Albert I. Chen

    OriginalPaper Open access 01 October 2018 Pages: 4102 - 4119

    

22. Evidence Supporting a Role for the Blood-Cerebrospinal Fluid Barrier Transporting Circulating Ghrelin into the Brain

    • Maia Uriarte
    • Pablo Nicolás De Francesco
    • Mario Perello

    OriginalPaper 02 October 2018 Pages: 4120 - 4134

    

23. Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain

    • Meritxell Llorca-Torralba
    • Fuencisla Pilar-Cuéllar
    • Esther Berrocoso

    OriginalPaper 03 October 2018 Pages: 4135 - 4150

    

24. Neuron-Type Specific Loss of CDKL5 Leads to Alterations in mTOR Signaling and Synaptic Markers

    • Ethan Schroeder
    • Li Yuan
    • Jyothi Arikkath

    OriginalPaper 04 October 2018 Pages: 4151 - 4162

    

25. Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

    • Samuel Kohtala
    • Wiebke Theilmann
    • Tomi Rantamäki

    OriginalPaper Open access 04 October 2018 Pages: 4163 - 4174

    

26. Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency

    • Renata H. Bahous
    • Marta Cosín-Tomás
    • Rima Rozen

    OriginalPaper 04 October 2018 Pages: 4175 - 4191

    

27. Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation

    • Ji-Hong Moon
    • Jae-Kyo Jeong
    • Sang-Youel Park

    OriginalPaper 05 October 2018 Pages: 4192 - 4202

    

28. Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System

    • Yoichiro Shinohara
    • Ayumu Konno
    • Hirokazu Hirai

    OriginalPaper 05 October 2018 Pages: 4203 - 4214

    

29. Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice

    • Tamara Heermann
    • Lillian Garrett
    • Sabine M. Hölter

    OriginalPaper 06 October 2018 Pages: 4215 - 4230

    

30. Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes

    • Elena Chierto
    • Anne Simon
    • Mehrnaz Jafarian-Tehrani

    OriginalPaper Open access 08 October 2018 Pages: 4231 - 4248

    

31. Immunosignature Analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

    • Oliver P. Günther
    • Jennifer L. Gardy
    • David M. Patrick

    OriginalPaper Open access 08 October 2018 Pages: 4249 - 4257

    

32. Methamphetamine (MA) Use Induces Specific Changes in LINE-1 Partial Methylation Patterns, Which Are Associated with MA-Induced Paranoia: a Multivariate and Neuronal Network Study

    • Rasmon Kalayasiri
    • Korakot Kraijak
    • Apiwat Mutirangura

    OriginalPaper 09 October 2018 Pages: 4258 - 4272

    

33. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo

    • Patrick Piero Bovio
    • Henriette Franz
    • Tanja Vogel

    OriginalPaper Open access 10 October 2018 Pages: 4273 - 4287

    

34. Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma

    • Antonio Inserra
    • Claudio Alberto Mastronardi
    • Ma-Li Wong

    ReviewPaper Open access 10 October 2018 Pages: 4288 - 4305

    

35. PDE3 Inhibitors Repurposed as Treatments for Age-Related Cognitive Impairment

    • Shuichi Yanai
    • Shogo Endo

    ReviewPaper 11 October 2018 Pages: 4306 - 4316

    

36. Absence of Mutation Enrichment for Genes Phylogenetically Conserved in the Olivocerebellar Motor Circuitry in a Cohort of Canadian Essential Tremor Cases

    • Jean-François Schmouth
    • Gabrielle Houle
    • Guy A. Rouleau

    OriginalPaper 12 October 2018 Pages: 4317 - 4321

37. Heterozygous Meg2 Ablation Causes Intraocular Pressure Elevation and Progressive Glaucomatous Neurodegeneration

    • Jacqueline Reinhard
    • Susanne Wiemann
    • Andreas Faissner

    OriginalPaper 12 October 2018 Pages: 4322 - 4345

    

38. Bezafibrate Upregulates Mitochondrial Biogenesis and Influence Neural Differentiation of Human-Induced Pluripotent Stem Cells

    • Justyna Augustyniak
    • Jacek Lenart
    • Leonora Buzanska

    OriginalPaper Open access 13 October 2018 Pages: 4346 - 4363

    

39. Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines

    • Manoj P. Dandekar
    • Ashwini Saxena
    • Albert J. Fenoy

    OriginalPaper 13 October 2018 Pages: 4364 - 4380

    

40. Aberrant Amygdala-Dependent Cued Fear Memory in Na⁺/Ca²⁺ Exchanger 1 Heterozygous Mice

    • Shigeki Moriguchi
    • Satomi Kita
    • Kohji Fukunaga

    OriginalPaper 15 October 2018 Pages: 4381 - 4394

    

41. Astrocyte-Like Cells Differentiated from Dental Pulp Stem Cells Protect Dopaminergic Neurons Against 6-Hydroxydopamine Toxicity

    • Kavina Ganapathy
    • Indrani Datta
    • Ramesh Bhonde

    OriginalPaper 16 October 2018 Pages: 4395 - 4413

    

42. Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice

    • Sandra de la Fuente
    • Alba Sansa
    • Rosa M. Soler

    OriginalPaper Open access 16 October 2018 Pages: 4414 - 4427

    

43. Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms

    • Lucas Taoro-Gonzalez
    • Yaiza M. Arenas
    • Vicente Felipo

    OriginalPaper 17 October 2018 Pages: 4428 - 4439

    

44. The Epigenetic Factor CBP Is Required for the Differentiation and Function of Medial Ganglionic Eminence-Derived Interneurons

    • Alejandro Medrano-Fernández
    • Jose M. Delgado-Garcia
    • Angel Barco

    OriginalPaper Open access 17 October 2018 Pages: 4440 - 4454

    

45. SNAP25 Gene Polymorphisms Protect Against Parkinson’s Disease and Modulate Disease Severity in Patients

    • Cristina Agliardi
    • Franca Rosa Guerini
    • Mario Clerici

    OriginalPaper 17 October 2018 Pages: 4455 - 4463

    

46. Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease

    • Marta Garcia-Miralles
    • Nur Amirah Binte Mohammad Yusof
    • Mahmoud A. Pouladi

    OriginalPaper 17 October 2018 Pages: 4464 - 4478

    

47. The Possibility of an Infectious Etiology of Alzheimer Disease

    • Ghulam M. Ashraf
    • Vadim V. Tarasov
    • Gjumrakch Aliev

    ReviewPaper 18 October 2018 Pages: 4479 - 4491

    

48. Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments

    • Courtney R. Sullivan
    • Catharine A. Mielnik
    • Robert E. McCullumsmith

    OriginalPaper 18 October 2018 Pages: 4492 - 4517

    

49. MAOA-VNTR Genotype Effects on Ventral Striatum-Hippocampus Network in Alzheimer’s Disease: Analysis Using Structural Covariance Network and Correlation with Neurobehavior Performance

    • Hsin-I Chang
    • Ya-Ting Chang
    • Chiung-Chih Chang

    OriginalPaper 18 October 2018 Pages: 4518 - 4529

    

50. Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer’s Disease and CNS-Related Disorders

    • Athanasios Alexiou
    • Georgia Soursou
    • Ghulam Md Ashraf

    ReviewPaper 18 October 2018 Pages: 4530 - 4538