Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model
Authors (first, second and last of 7)
Collection
Tumor Immunology
Tumor immunology is to gain insights in the interaction between the immune system and tumors, which is crucial for our understanding on the mechanisms of both tumor elimination and tumor escaping. Exploiting this knowledge leads to the development of novel cancer diagnostics and therapy.
All article types accepted.
Editors
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Dr. Cun Wang
Dr. Cun Wang obtained his Ph.D. degree in 2012 in Biochemistry and Molecular Biology from Fudan University, China. In 2012, he joined the laboratory of Prof. Wenxin Qin at Shanghai Cancer Institute, China. From 2016 to 2019, he joined the group of Prof. René Bernards at the Netherlands Cancer Institute in Amsterdam to investigate drug resistance in liver cancer. In 2019, he was appointed as professor at Shanghai Cancer Institute. His laboratory focuses on identifying powerful therapeutic strategies for liver cancer through functional genetic screens.
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Dr. Xiaohang Qiao
Dr. Xiaohang Qiao obtained her Ph.D. degree in 2010 on molecular immunology from the Institute of Biophysics, Chinese Academy of Sciences. From 2010 to 2016, she joined the group of Prof. Jacques Neefjes at the Netherlands Cancer Institute (Nederlands Kanker Instituut, NKI) to investigate the molecular mechanisms of anti-cancer drugs. After that, she joined the laboratory of Prof. Lotje Zuur at NKI to explore the novel therapeutic targets and neoadjuvant immunotherapy for head and neck cancer (HNC). In 2017, she was appointed as Associate Staff Scientist in the department of Tumor Biology and Immunology at NKI.
Articles (27 in this collection)
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LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation
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The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration
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Pathological response and tumor stroma immunogenic features predict long-term survival in non-small cell lung cancer after neoadjuvant chemotherapy
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SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma
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TRPV1 inhibition suppresses non-small cell lung cancer progression by inhibiting tumour growth and enhancing the immune response
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FAP is a prognostic marker, but not a viable therapeutic target for clinical translation in HNSCC
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High-plex spatial transcriptomic profiling reveals distinct immune components and the HLA class I/DNMT3A/CD8 modulatory axis in mismatch repair-deficient endometrial cancer
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Plasma cell signatures predict prognosis and treatment efficacy for lung adenocarcinoma
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Immune characteristics associated with lymph node metastasis in early-stage NSCLC
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Ubiquilin-4 induces immune escape in gastric cancer by activating the notch signaling pathway
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Single-cell transcriptomic profiling reveals immune cell heterogeneity in acute myeloid leukaemia peripheral blood mononuclear cells after chemotherapy
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Genomic analysis and filtration of novel prognostic biomarkers based on metabolic and immune subtypes in pancreatic cancer
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Effect of infiltrating immune cells in tumor microenvironment on metastasis of hepatocellular carcinoma
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Transglutaminases are oncogenic biomarkers in human cancers and therapeutic targeting of TGM2 blocks chemoresistance and macrophage infiltration in pancreatic cancer
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Comprehensive analysis of clinical prognostic features and tumor microenvironment landscape of CD11b+CD64+ patients with acute myeloid leukemia
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Increased SPRY1 expression activates NF-κB signaling and promotes pancreatic cancer progression by recruiting neutrophils and macrophages through CXCL12-CXCR4 axis
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Targeting CD43 optimizes cancer immunotherapy through reinvigorating antitumor immune response in colorectal cancer
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Involvement of ACACA (acetyl-CoA carboxylase α) in the lung pre-metastatic niche formation in breast cancer by senescence phenotypic conversion in fibroblasts
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TRIM44 regulates tumor immunity in gastric cancer through LOXL2-dependent extracellular matrix remodeling
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Kavain ablates the radio-resistance of IDH-wildtype glioblastoma by targeting LITAF/NF-κB pathway
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TNFR2 antagonistic antibody induces the death of tumor infiltrating CD4+Foxp3+ regulatory T cells
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Low-dose anti-VEGFR2 therapy promotes anti-tumor immunity in lung adenocarcinoma by down-regulating the expression of layilin on tumor-infiltrating CD8+T cells
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Blockade of USP14 potentiates type I interferon signaling and radiation-induced antitumor immunity via preventing IRF3 deubiquitination
Authors (first, second and last of 13)
