Collection
Special Issue in Honor of Prof. Thomas A. Baillie
Special Issue in honor of Prof. Thomas A. Baillie for his many contributions to drug metabolism and drug discovery
Editors
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Cyrus Khojasteh-Bakht
Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA 94080, USA
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Mark Grillo
Drug Metabolism and Pharmacokinetics, Cytokinetics, Inc., South San Francisco, CA 94080, USA
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Kaushik Mitra
Discovery, Product Development & Supply, Preclinical Sciences & Translational Safety, Drug Metabolism and Pharmacokinetics, Janssen Pharmaceuticals, Springhouse, PA 19477, USA
Articles (13 in this collection)
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The metabolic fate of izencitinib, a gut-selective pan-JAK inhibitor, in humans. Identification of unusual fecal metabolites and implications for MIST evaluation
Authors (first, second and last of 10)
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Stable isotope applications in drug development and the elucidation of mechanisms of drug metabolism
Authors
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Acyl-CoA thioesters as chemically-reactive intermediates of carboxylic acid-containing drugs
Authors
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The past decade of Genentech experience in elucidation of novel reaction mechanisms in drug metabolism
Authors (first, second and last of 4)
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A MIST conception: what has been learned from twenty years of human metabolite safety assessment?
Authors
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