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Reactor-Produced Therapeutic Radionuclides

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Radiopharmaceuticals for Therapy

Abstract

Therapeutic radioisotopes are generally artificially produced using research reactors or particle accelerators. Since most therapeutic radioisotopes are neutron rich and subsequently decay by beta (β−)-particle emission, the irradiation of stable nuclei under neutron bombardment is a major important strategy for production. Most reactors are owned and operated by federal governments, so the accessibility and support of these facilities continues to be an important factor to insure the availability of a wide variety of reactor-produced radioisotopes. In this chapter the principle reactor production and processing strategies are described for a wide variety of radioisotopes which have important therapeutic applications in nuclear medicine, oncology interventional cardiology/radiology, and related disciplines.

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  1. Nuclear Security and Isotope Division, Oak Ridge National Laboratory, OAK RIDGE, USA

    F. F. (Russ) Knapp

  2. Isotope Production and Applications Division, Bhabha Atomic Research Centre, Mumbai, India

    Ashutosh Dash

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Knapp, F.F.(., Dash, A. (2016). Reactor-Produced Therapeutic Radionuclides. In: Radiopharmaceuticals for Therapy . Springer, New Delhi. https://doi.org/10.1007/978-81-322-2607-9_5

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