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Polymer Embedded Nanocrystalline Titania: A New Generation Sorbent for the Separation of 77As from Ge for Biomedical Applications

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Abstract

The present work demonstrates the utility of polymer embedded nanocrystalline titania (TiP) as a new, accessible and viable solid sorbent for the chromatographic separation of high specific activity 77As from neutron irradiated natural GeO2. Experimental parameters such as distribution ratios (K d), equilibrium sorption capacity, breakthrough capacity and separation yields were determined. A two-step ion-exchange procedure was developed to avail 77As, from irradiated Ge in alkaline medium. The first step involved removal of the bulk Ge from 77As by selective sorption of Ge ions on a TiP column at pH 13. Subsequently, the effluent solution containing 77As was further purified and concentrated by sorption on a small TiP column at pH 10. 77As could be eluted from the second column in 2–3 mL of 0.1 M NaOH solution with >80% radiochemical yield. The 77As obtained by this method was found to have insignificantly small level of radiocontaminants.

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Acknowledgments

The authors are grateful to Prof. V. Venugopal, Director, Radiochemistry and Isotope Group for his constant encouragement and continued support to this programme. Thanks are due to the Analytical Chemistry Division, BARC for the ICP-AES and GF-AAS studies. The authors wish to express their sincere thanks to Mr. Pritam Bansode for making the drawings of this manuscript.

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Authors and Affiliations

  1. Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai, 400085, India

    Rubel Chakravarty, Ramu Ram, K. C. Jagdeesan, Meera Venkatesh & Ashutosh Dash

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  1. Rubel Chakravarty
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  2. Ramu Ram
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  3. K. C. Jagdeesan
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  4. Meera Venkatesh
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  5. Ashutosh Dash
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Correspondence to Ashutosh Dash.

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Chakravarty, R., Ram, R., Jagdeesan, K.C. et al. Polymer Embedded Nanocrystalline Titania: A New Generation Sorbent for the Separation of 77As from Ge for Biomedical Applications. Chromatographia 74, 531–540 (2011). https://doi.org/10.1007/s10337-011-2113-4

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  • DOI: https://doi.org/10.1007/s10337-011-2113-4

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