Chemical and biological aspects of posaconazole as a classic antifungal agent with non-classical properties: highlighting a tetrahydrofuran-based drug toward generation of new drugs Sakineh DadashpourElham GhobadiSaeed Emami Review Article 19 May 2022 Pages: 833 - 850
Isoindolone derivatives as novel potential anti-Alzheimer’s candidates: synthesis, in silico, and AChE inhibitory activity evaluation Erik Andrade-JorgeFernando Rivera-SánchezAdelfo Reyes-Ramírez Original Research 09 April 2022 Pages: 851 - 866
Discovery of novel donepezil-M30D hybrids with neuroprotective properties for Alzheimer’s disease treatment Andrés F. YepesCamilo A. RamírezRafael Posada-Duque Original Research 09 April 2022 Pages: 867 - 885
Novel norsufentanil analogues containing triazole ring; synthesis, radioligand binding assay, and pharmacological evaluation Majid NamiPeyman SalehiMehrdad Faizi Original Research 12 April 2022 Pages: 886 - 893
Evaluation of novel multifunctional organoselenium compounds as potential cholinesterase inhibitors against Alzheimer’s disease Dina A. RefaayDalia M. AhmedSaad Shaaban Original Research 12 April 2022 Pages: 894 - 904
Design, synthesis of amide derivatives of scutellarin and their antileukemia and neuroprotective activities Tong HanChunyu JiangChenghao Jin Original Research 19 April 2022 Pages: 905 - 915
Hybrid molecules of scutellarein and 3, 5, 6-trimethylpyrazine-2-formic acid linked with polar amino acid for ischemic stroke Shuxia WuMingji LiuYongxi Dong Original Research 22 April 2022 Pages: 916 - 924
Synthesis, cytotoxicities, and carbonic anhydrase inhibition activities of pyrazoline–benzenesulfonamide derivatives harboring phenol/polyphenol moieties Sinan BilginerSanaa K. BardaweelCavit Kazaz Original Research 23 April 2022 Pages: 925 - 935
Novel orthodiphenyl five-member N-heteroaromatic compounds as potent anticancer cell agents Shijia HuYunqi LiYihua Chen Original Research 27 April 2022 Pages: 936 - 948
Synthesis and antimycobacterial evaluation of fluoroquinolones derivatives coupled with isoprenyl moiety at the C-7 position César A. RibeiroDijovani B. dos ReisMauricio F. Saraiva Original Research 29 April 2022 Pages: 949 - 959
Dual HDAC–BRD4 inhibitors endowed with antitumor and antihyperalgesic activity Soumia MaachNiccolò ChiaramonteMaria Novella Romanelli Original Research Open access 03 May 2022 Pages: 960 - 974
N-Substituted 4-sulfamoylbenzoic acid derivatives as inhibitors of cytosolic phospholipase A2α Daniel BoreckiMatthias Lehr Original Research Open access 05 May 2022 Pages: 975 - 992
Microwave-assisted synthesis and evaluation of their antiproliferative, antimicrobial, activities and DNA Binding studies of (3-Methyl-7H-furo[2,3-f]chromen-2-yl)(aryl)methanones Ravinder DharavathM. SarasijaSreenu Daravath Original Research 05 May 2022 Pages: 993 - 1002
Synthesis and evaluation of new sartan derivatives Bertsetseg DalaijargalLe MiZhi-Long Chen Original Research 06 May 2022 Pages: 1003 - 1010
N-Phosphorylation of daunorubicin—synthetic approaches and antiproliferative properties of the products Aleksandra A. MoiseevaOleg I. ArtyushinValery K. Brel Original Research 06 May 2022 Pages: 1011 - 1025
Synthesis, in-vitro biological evaluation, and molecular docking study of novel spiro-β-lactam-isatin hybrids Aliasghar JarrahpourZahra JowkarNamık Özdemir Original Research 10 May 2022 Pages: 1026 - 1034
Design, synthesis, and biological evaluation of novel 2-acetylphenol-rivastigmine hybrids as potential multifunctional agents for the treatment of Alzheimer’s disease Cong DengJing MiHui Li Original Research 14 May 2022 Pages: 1035 - 1048
Platanic acid derived amides are more cytotoxic than their corresponding oximes Marie KozubekSophie HoenkeRené Csuk Original Research Open access 16 May 2022 Pages: 1049 - 1059
