1. Cyclic AMP as a second messenger in the skeletal actions of parathyroid hormone: A decade-old hypothesis

   • William A. Peck

   Editorial Pages: 1 - 4

2. Plasma prostaglandin E levels in Paget’s disease: Effect of indomethacin

   • Daniel T. Baran
   • Bernard M. Jaffe
   • Louis V. Avioli

   Clinical Investigation Pages: 5 - 6

3. Effects of changing hydrogen ion, carbonic acid, and bicarbonate concentrations on bone resorption in vitro

   • Jesus H. Dominguez
   • Lawrence G. Raisz

   Laboratory Investigations Pages: 7 - 13

4. Influence of magnesium depletion on matrix-induced endochondral bone formation

   • Ruth Schwartz
   • A. H. Reddi

   Laboratory Investigations Pages: 15 - 20

5. Bone mineralization and metabolism of³H-25-hydroxyvitamin D₃ in thyroparathyroidectomized rats treated with parathyroid extract

   • J. I. Rader
   • G. A. Howard
   • D. J. Baylink

   Laboratory Investigations Pages: 21 - 26

6. Enzymatic properties of the Ca²⁺-Binding glycoprotein isolated from preosseous cartilage

   • N. Stagni
   • G. Furlan
   • B. de Bernard

   Laboratory Investigations Pages: 27 - 32

7. Effect of multiplication-stimulating activity on DNA and protein synthesis in cultured fetal rat calvaria

   • Ernesto Canalis
   • Lawrence G. Raisz

   Laboratory Investigations Pages: 33 - 39

8. Incorporation of serum albumin into the developing dentine and enamel matrix in the rabbit incisor

   • Yasushi Kinoshita

   Laboratory Investigations Pages: 41 - 46

9. Enamel structure in some therapsids and mesozoic mammals

   • J. W. Osborn
   • J. Hillman

   Laboratory Investigations Pages: 47 - 61

10. Vaterite, a constituent of the eggshells of the nonparasitic cuckoos,Guira guira andCrotophagi ani

    • R. G. Board
    • H. R. Perrott

    Laboratory Investigations Pages: 63 - 69

11. A bone-fixing trephine for large-diameter iliac biopsies in dogs

    • Claes Schuyt
    • A. Meulemans
    • W. H. van Eek

    Laboratory Investigations Pages: 71 - 73

12. A model for the distribution of HAP crystallites in bone: An hypothesis

    • C. W. McCutchen

    Commentaries Pages: 75 - 75

13. Paget’s disease of bone and hyperparathyroidism: Coincidence or causal relationship?

    • A. M. Parfitt

    Commentaries Pages: 75 - 76

14. Announcements

    Announcement Pages: 77 - 78

15. Long-term culture of cells from bone affected by Paget’s disease

    • B. G. Mills
    • F. R. Singer
    • P. A. Holst

    Clinical Investigations Pages: 79 - 87

16. Change in response with age of human articular cartilage to plasma somatomedin activity

    • I. K. Ashton
    • J. A. Matheson

    Clinical Investigations Pages: 89 - 94

17. Study of an asymmetric ESR signal in X-irradiated human tooth enamel

    • K. Sato

    Clinical Investigations Pages: 95 - 99

18. Orientation of apatite in single osteon samples as studied by pole figures

    • A. Ascenzi
    • E. Bonucci
    • N. Roveri

    Clinical Investigations Pages: 101 - 105

19. A study of some properties of a sample of bovine cortical bone using ultrasound

    • Sidney Lees
    • John D. Heeley
    • Paul F. Cleary

    Laboratory Investigations Pages: 107 - 117

20. Potassium, sodium, and the intracellular fluid space of cells from bone

    • John S. Brand
    • Janet Cushing
    • Thomas Hefley

    Laboratory Investigations Pages: 119 - 125

21. Lattice parameters and cation distribution of solid solutions of calcium and strontium hydroxyapatite

    • H. J. M. Heijligers
    • F. C. M. Driessens
    • R. M. H. Verbeeck

    Laboratory Investigations Pages: 127 - 131

22. Experimental alveolar bone loss in the monkey evaluated by¹²⁵I absorptiometry

    • Ernest Hausmann
    • Lance F. Ortman
    • Nell Sedransk

    Laboratory Investigations Pages: 133 - 139

23. Regulation of intestinal calcium-binding protein in rats: Role of parathyroid hormone

    • Monique Thomasset
    • Paulette Cuisinier-Gleizes
    • Felix Bronner

    Laboratory Investigations Pages: 141 - 145

24. Dissociation of renal cyclic AMP and phosphate responses to parathyroid hormone in uremia

    • J. E. Russell
    • M. Kleerekoper
    • L. V. Avioli

    Laboratory Investigations Pages: 147 - 154

25. Regulation of calcium transport in isolated periosteal cells, effects of hormones and metabolic inhibitors

    • P. J. Nijweide
    • A. van der Plas

    Laboratory Investigations Pages: 155 - 161

26. Aspartic acid-rich proteins: Major components of the soluble organic matrix of mollusk shells

    • Stephen Weiner

    Laboratory Investigations Pages: 163 - 167

27. The occurrence of chondroitin-6-sulphate in adult human compact bone tissue

    • A. Hjerpe
    • F. P. Reinholt
    • B. Engfeldt

    Rapid Communications Pages: 169 - 171

28. Cortisol enhancement of PTH-stimulated cyclic AMP accumulation in cultured fetal rat long bone rudiments

    • Theodore J. Hahn
    • Linda R. Halstead

    Rapid Communications Pages: 173 - 175

29. Infrared absorption bands from NCO⁻ and NCN²⁻ in heated carbonate-containing apatites prepared in the presence of NH₄ ⁺ Ions

    • S. E. P. Dowker
    • J. C. Elliott

    Rapid Communications Pages: 177 - 178

30. A technique for microangiographic analysis of bone

    • James L. Berry

    Commentaries Pages: 179 - 180

31. Presence of “crystal ghosts” in bone nodules

    • E. Bonucci

    Commentaries Pages: 181 - 182

32. Announcements

    Announcement Pages: 183 - 184

33. Significance of early increase in stable and radioactive plasma calcium after parathyroidectomy in primary hyperparathyroidism

    • G. F. Mazzuoli
    • E. D’Erasmo
    • L. Malaguti Aliberti

    Clinical Investigations Pages: 185 - 191

34. Regulation of hormone-induced cyclic AMP response to parathyroid hormone and prostaglandin E₂ in cells cultured from human giant cell tumors of bone

    • Steven R. Goldring
    • Jean-Michel Dayer
    • Stephen M. Krane

    Clinical Investigations Pages: 193 - 200

35. Comparison of the effects of 1,25-dihydroxycholecalciferol, prostaglandin E₂, and osteoclast-activating factor with parathyroid hormone on the ultrastructure of osteoclasts in cultured long bones of fetal rats

    • Marijke E. Holtrop
    • Lawrence G. Raisz

    Laboratory Investigations Pages: 201 - 205

36. A cat model for the evaluation of mechanisms of bone resorption: Induction of bone loss by simulated immune complexes and inhibition by indomethacin

    • Mahmoud Torbinejad
    • James Clagett
    • David Engel

    Laboratory Investigations Pages: 207 - 214

37. Comparison of the effects of a potent synthetic analog of bovine parathyroid hormone with native bPTH-(1-84) and synthetic bPTH-(1-34) on bone resorption and collagen synthesis

    • Lawrence G. Raisz
    • Joseph Lorenzo
    • Michael Rosenblatt

    Laboratory Investigations Pages: 215 - 218

38. A study of the action of calcitonin by its effects on lead-induced hypercalcemia

    • Roy V. Talmage
    • Carole J. VanderWiel

    Laboratory Investigations Pages: 219 - 224

39. Early osteogenesis in compact bone isografts: A quantitative study of the contributions of the different graft cells

    • J. Craig Gray
    • M. W. Elves

    Laboratory Investigations Pages: 225 - 237

40. Analysis of electron-excess and electron-deficient centers in x-ray-irradiated tricalcium phosphates by electron spin resonance spectroscopy

    • Y. Doi
    • T. Aoba
    • Y. Moriwaki

    Laboratory Investigations Pages: 239 - 244

41. Ectopic calcification in lambs from feeding the plantCestrum diurnum

    • Charles F. Simpson
    • M. L. Bruss

    Laboratory Investigations Pages: 245 - 250

42. Cathepsin D: Ultra-immunohistochemical localization in dentinogenesis

    • H. Nygren
    • B. Persliden
    • A. Linde

    Laboratory Investigations Pages: 251 - 256

43. Announcements

    Announcement Pages: 257 - 258