Articles

1. Targeted gene delivery systems for T-cell engineering

   • Fengling Wang
   • Yong Huang
   • Wei Wang

   Review 16 May 2024

   

2. SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma

   • Ping Zhou
   • Wei Yao
   • Fan Zhu

   Research 16 May 2024

   

3. Deciphering fatty acid biosynthesis-driven molecular subtypes in pancreatic ductal adenocarcinoma with prognostic insights

   • Junyi Xu
   • Mingzhu Liu
   • Ping Lu

   Research 16 May 2024

   

4. Research advances in the molecular classification of gastric cancer

   • Dike Shi
   • Zihan Yang
   • Qingqu Guo

   Review Open access 08 May 2024

   

5. Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment

   • Zhanyi Zhang
   • Xuebo Chen
   • Shengnan Ren

   Correction Open access 30 April 2024

6. Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model

   • Siavash Mashhouri
   • Amirhossein Rahmati
   • Shokrollah Elahi

   Research Open access 26 April 2024

   

7. Rituximab potentially improves clinical outcomes of CAR-T therapy for r/r B-ALL via sensitizing leukemia cells to CAR-T-mediated cytotoxicity and reducing CAR-T exhaustion

   • Yangzi Li
   • Qingya Cui
   • Xiaowen Tang

   Research Open access 25 April 2024

   

8. LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation

   • Zhiyuan Jiang
   • Qianru Huang
   • Hui Zhao

   Research 24 April 2024

   

9. Chordoma cells possess bone-dissolving activity at the bone invasion front

   • Katsuhiro Kawaai
   • Yumiko Oishi
   • Koichi Matsuo

   Research Open access 23 April 2024

   

10. Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis

    • Yujing Huang
    • Dongyan Cao
    • Aina He

    Research Open access 23 April 2024

    

11. Correction to: Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling

    • Wanru Zhang
    • Xiali Qin
    • Hailong Cao

    Correction 16 April 2024

    

12. Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma

    • Shengqiang Mao
    • Yilong Wang
    • Li Zhang

    Research 15 April 2024

    

13. The emerging role of CARM1 in cancer

    • Zizhuo Xie
    • Yuan Tian
    • Na Xie

    Review Open access 15 April 2024

    

14. Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer

    • Soon-Chan Kim
    • Ha-Young Seo
    • Ja-Lok Ku

    Research Open access 15 April 2024

    

15. Downregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration

    • Chen-Yang Tao
    • Xiao-Ling Wu
    • Jia Fan

    Research Open access 12 April 2024

    

16. Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling

    • Jing Dong
    • Ji Che
    • Jun Zhang

    Research 09 April 2024

    

17. Hedgehog ligand and receptor cooperatively regulate EGFR stability and activity in non-small cell lung cancer

    • Aidi Huang
    • Junyao Cheng
    • Minzhang Cheng

    Research 03 April 2024

    

18. Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis

    • Regine Marlin
    • Jean-Samuel Loger
    • Mehdi Jean-Laurent

    Research Open access 02 April 2024

    

19. Efficacy of programmed cell death 1 inhibitor maintenance after chimeric antigen receptor T cells in patients with relapsed/refractory B-cell non-Hodgkin-lymphoma

    • Xiangke Xin
    • Xiaojian Zhu
    • Yicheng Zhang

    Research 02 April 2024

    

20. IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling

    • Tian-Hao Li
    • Bang-Bo Zhao
    • Wei-Bin Wang

    Research 27 March 2024

    

21. 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment

    • Zhanyi Zhang
    • Xuebo Chen
    • Shengnan Ren

    Review Open access 23 March 2024

    

22. DNA hypomethylation patterns and their impact on the tumor microenvironment in colorectal cancer

    • He Huang
    • Qian Li
    • Chunlian Ke

    Research 23 March 2024

    

23. Multi-dimensional characterization of apoptosis in the tumor microenvironment and therapeutic relevance in melanoma

    • Jing Ye
    • Benliang Wei
    • Hong Liu

    Research Open access 19 March 2024

    

24. The Ribonuclease ZC3H12A is required for self-inflicted DNA breaks after DNA damage in small cell lung cancer cells

    • Mingjun Lu
    • Qing Gao
    • Teng Ma

    Correspondence 18 March 2024

    

25. Mapping the immune terrain in lung adenocarcinoma progression: Tfh-like cells in tertiary lymphoid structures

    • Jialei Gong
    • Di Yu

    Comment 16 March 2024

    

26. Identification of a novel gene signature related to prognosis and metastasis in gastric cancer

    • Joseba Elizazu
    • Aizpea Artetxe-Zurutuza
    • Estefania Carrasco-Garcia

    Research Open access 13 March 2024

    

27. CAFs vs. TECs: when blood feuds fuel cancer progression, dissemination and therapeutic resistance

    • Diane Coursier
    • Fernando Calvo

    Review Open access 07 March 2024

    

28. STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma

    • Ziying Zhao
    • Yuan Chu
    • Meidong Xu

    Research Open access 04 March 2024

    

29. The predictive significance of chromobox family members in prostate cancer in humans

    • Xiaoting Xu
    • Cong Lai
    • Kewei Xu

    Research 01 March 2024

    

30. The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration

    • Umair Majid
    • Christian Holst Bergsland
    • Ragnhild A. Lothe

    Research Open access 26 February 2024

    

31. Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma

    • Tingyu Liu
    • Xin Yue
    • Ran-Yi Liu

    Research 23 February 2024

    

32. PIN1 promotes the metastasis of cholangiocarcinoma cells by RACK1-mediated phosphorylation of ANXA2

    • Yuming Wang
    • Yiwei Liu
    • Xiaofeng Wu

    Research 22 February 2024

    

33. GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer

    • Haiping Lin
    • Yang Luo
    • Ming Zhong

    Research 22 February 2024

    

34. O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency

    • Fu-Ying Zhao
    • Xue Chen
    • Hua-Qin Wang

    Research 12 February 2024

    

35. Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis

    • Ying Xue
    • Cong Xue
    • Wei Song

    Review 07 February 2024

    

36. Repaglinide restrains HCC development and progression by targeting FOXO3/lumican/p53 axis

    • Yifei Tan
    • Yongjie Zhou
    • Jiayin Yang

    Research 07 February 2024

    

37. Pathological response and tumor stroma immunogenic features predict long-term survival in non-small cell lung cancer after neoadjuvant chemotherapy

    • Shuaibo Wang
    • Xujie Sun
    • Lin Yang

    Research 06 February 2024

    

38. Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression

    • Kunwei Peng
    • Yongxiang Liu
    • Liangping Xia

    Research 05 February 2024

    

39. OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination

    • Liqun Peng
    • Tiangen Wu
    • Yufeng Yuan

    Research Open access 05 February 2024

    

40. A novel risk score system based on immune subtypes for identifying optimal mRNA vaccination population in hepatocellular carcinoma

    • Hongkai Zhuang
    • Chenwei Tang
    • Yajin Chen

    Research 05 February 2024

    

41. DNA-methylome-derived epigenetic fingerprint as an immunophenotype indicator of durable clinical immunotherapeutic benefits in head and neck squamous cell carcinoma

    • Rui Li
    • Xin Wen
    • Xin-Ran Tang

    Research 05 February 2024

    

42. Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling

    • Wanru Zhang
    • Xiali Qin
    • Hailong Cao

    Research 05 February 2024

    

43. Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue

    • Alexandra Trinks
    • Miha Milek
    • Philip Bischoff

    Research Open access 01 February 2024

    

44. Omics-based molecular classifications empowering in precision oncology

    • Zhaokai Zhou
    • Ting Lin
    • Zaoqu Liu

    Review 31 January 2024

    

45. NK cells as powerful therapeutic tool in cancer immunotherapy

    • Mao Huang
    • Yixuan Liu
    • Wei Xiong

    Review 03 January 2024

    

46. Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8 + T cells

    • Xinrui Wu
    • Yinjie Zhu
    • Jiahua Pan

    Brief Report 02 January 2024

    

47. Asymmetric post-translational modifications regulate the nuclear translocation of STAT3 homodimers in response to leukemia inhibitory factor

    • Mickael Diallo
    • Constança Pimenta
    • Federico Herrera

    Brief Report Open access 27 December 2023

    

48. ITGB2-ICAM1 axis promotes liver metastasis in BAP1-mutated uveal melanoma with retained hypoxia and ECM signatures

    • Jiaoduan Li
    • Dongyan Cao
    • Dongxi Xiang

    Research 27 December 2023

    

49. Sirtuin 5-mediated deacetylation of TAZ at K54 promotes melanoma development

    • Garam Kim
    • Poshan Yugal Bhattarai
    • Hong Seok Choi

    Research 19 December 2023

    

50. ATF3-induced activation of NF-κB pathway results in acquired PARP inhibitor resistance in pancreatic adenocarcinoma

    • Yang Liu
    • Yizhi Cao
    • Baiyong Shen

    Research 15 December 2023