ONECUT2 is a druggable driver of luminal to basal breast cancer plasticity Irene ZamoraMirian GutiérrezMirja Rotinen Research Open access 31 May 2024
HVEM in acute lymphocytic leukemia facilitates tumour immune escape by inhibiting CD8+ T cell function Yujia LiuLixiang WangWei Yi Research 29 May 2024
OrganoIDNet: a deep learning tool for identification of therapeutic effects in PDAC organoid-PBMC co-cultures from time-resolved imaging data Nathalia FerreiraAjinkya KulkarniM. Andrea Markus Research Open access 28 May 2024
A systematic review on the culture methods and applications of 3D tumoroids for cancer research and personalized medicine Jessica KallaJanette PfneisslGerda Egger Review Open access 28 May 2024
Targeted gene delivery systems for T-cell engineering Fengling WangYong HuangWei Wang Review 16 May 2024
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway in hepatocellular carcinoma Ping ZhouWei YaoFan Zhu Research 16 May 2024
Deciphering fatty acid biosynthesis-driven molecular subtypes in pancreatic ductal adenocarcinoma with prognostic insights Junyi XuMingzhu LiuPing Lu Research 16 May 2024
Research advances in the molecular classification of gastric cancer Dike ShiZihan YangQingqu Guo Review Open access 08 May 2024
Correction to: 3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment Zhanyi ZhangXuebo ChenShengnan Ren Correction Open access 30 April 2024
Targeting Dectin-1 and or VISTA enhances anti-tumor immunity in melanoma but not colorectal cancer model Siavash MashhouriAmirhossein RahmatiShokrollah Elahi Research Open access 26 April 2024
Rituximab potentially improves clinical outcomes of CAR-T therapy for r/r B-ALL via sensitizing leukemia cells to CAR-T-mediated cytotoxicity and reducing CAR-T exhaustion Yangzi LiQingya CuiXiaowen Tang Research Open access 25 April 2024
LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation Zhiyuan JiangQianru HuangHui Zhao Research 24 April 2024
Chordoma cells possess bone-dissolving activity at the bone invasion front Katsuhiro KawaaiYumiko OishiKoichi Matsuo Research Open access 23 April 2024
Exploring the impact of PDGFD in osteosarcoma metastasis through single-cell sequencing analysis Yujing HuangDongyan CaoAina He Research Open access 23 April 2024
Correction to: Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling Wanru ZhangXiali QinHailong Cao Correction 16 April 2024
Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals immune suppression subtypes and establishes a novel signature for determining the prognosis in lung adenocarcinoma Shengqiang MaoYilong WangLi Zhang Research 15 April 2024
Establishment, characterization, and biobanking of 36 pancreatic cancer organoids: prediction of metastasis in resectable pancreatic cancer Soon-Chan KimHa-Young SeoJa-Lok Ku Research Open access 15 April 2024
Downregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration Chen-Yang TaoXiao-Ling WuJia Fan Research Open access 12 April 2024
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling Jing DongJi CheJun Zhang Research 09 April 2024
Hedgehog ligand and receptor cooperatively regulate EGFR stability and activity in non-small cell lung cancer Aidi HuangJunyao ChengMinzhang Cheng Research 03 April 2024
Copy number signatures and CCNE1 amplification reveal the involvement of replication stress in high-grade endometrial tumors oncogenesis Regine MarlinJean-Samuel LogerMehdi Jean-Laurent Research Open access 02 April 2024
Efficacy of programmed cell death 1 inhibitor maintenance after chimeric antigen receptor T cells in patients with relapsed/refractory B-cell non-Hodgkin-lymphoma Xiangke XinXiaojian ZhuYicheng Zhang Research 02 April 2024
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling Tian-Hao LiBang-Bo ZhaoWei-Bin Wang Research 27 March 2024
3D bioprinted tumor model: a prompt and convenient platform for overcoming immunotherapy resistance by recapitulating the tumor microenvironment Zhanyi ZhangXuebo ChenShengnan Ren Review Open access 23 March 2024
DNA hypomethylation patterns and their impact on the tumor microenvironment in colorectal cancer He HuangQian LiChunlian Ke Research 23 March 2024
Multi-dimensional characterization of apoptosis in the tumor microenvironment and therapeutic relevance in melanoma Jing YeBenliang WeiHong Liu Research Open access 19 March 2024
The Ribonuclease ZC3H12A is required for self-inflicted DNA breaks after DNA damage in small cell lung cancer cells Mingjun LuQing GaoTeng Ma Correspondence 18 March 2024
Mapping the immune terrain in lung adenocarcinoma progression: Tfh-like cells in tertiary lymphoid structures Jialei GongDi Yu Comment 16 March 2024
Identification of a novel gene signature related to prognosis and metastasis in gastric cancer Joseba ElizazuAizpea Artetxe-ZurutuzaEstefania Carrasco-Garcia Research Open access 13 March 2024
CAFs vs. TECs: when blood feuds fuel cancer progression, dissemination and therapeutic resistance Diane CoursierFernando Calvo Review Open access 07 March 2024
STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma Ziying ZhaoYuan ChuMeidong Xu Research Open access 04 March 2024
The predictive significance of chromobox family members in prostate cancer in humans Xiaoting XuCong LaiKewei Xu Research 01 March 2024
The prognostic effect of tumor-associated macrophages in stage I-III colorectal cancer depends on T cell infiltration Umair MajidChristian Holst BergslandRagnhild A. Lothe Research Open access 26 February 2024
Nilotinib in combination with sunitinib renders MCL-1 for degradation and activates autophagy that overcomes sunitinib resistance in renal cell carcinoma Tingyu LiuXin YueRan-Yi Liu Research 23 February 2024
PIN1 promotes the metastasis of cholangiocarcinoma cells by RACK1-mediated phosphorylation of ANXA2 Yuming WangYiwei LiuXiaofeng Wu Research 22 February 2024
GDF15 induces chemoresistance to oxaliplatin by forming a reciprocal feedback loop with Nrf2 to maintain redox homeostasis in colorectal cancer Haiping LinYang LuoMing Zhong Research 22 February 2024
O-GlcNAcylation of TRIM29 and OGT translation forms a feedback loop to promote adaptive response of PDAC cells to glucose deficiency Fu-Ying ZhaoXue ChenHua-Qin Wang Research 12 February 2024
Emerging roles of deubiquitinating enzymes in actin cytoskeleton and tumor metastasis Ying XueCong XueWei Song Review 07 February 2024
Repaglinide restrains HCC development and progression by targeting FOXO3/lumican/p53 axis Yifei TanYongjie ZhouJiayin Yang Research 07 February 2024
Pathological response and tumor stroma immunogenic features predict long-term survival in non-small cell lung cancer after neoadjuvant chemotherapy Shuaibo WangXujie SunLin Yang Research 06 February 2024
Targeting MEK/COX-2 axis improve immunotherapy efficacy in dMMR colorectal cancer with PIK3CA overexpression Kunwei PengYongxiang LiuLiangping Xia Research 05 February 2024
OTUB1 accelerates hepatocellular carcinoma by stabilizing RACK1 via its non-canonical ubiquitination Liqun PengTiangen WuYufeng Yuan Research Open access 05 February 2024
A novel risk score system based on immune subtypes for identifying optimal mRNA vaccination population in hepatocellular carcinoma Hongkai ZhuangChenwei TangYajin Chen Research 05 February 2024
DNA-methylome-derived epigenetic fingerprint as an immunophenotype indicator of durable clinical immunotherapeutic benefits in head and neck squamous cell carcinoma Rui LiXin WenXin-Ran Tang Research 05 February 2024
Microbial metabolite trimethylamine-N-oxide induces intestinal carcinogenesis through inhibiting farnesoid X receptor signaling Wanru ZhangXiali QinHailong Cao Research 05 February 2024
Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue Alexandra TrinksMiha MilekPhilip Bischoff Research Open access 01 February 2024
Omics-based molecular classifications empowering in precision oncology Zhaokai ZhouTing LinZaoqu Liu Review 31 January 2024
NK cells as powerful therapeutic tool in cancer immunotherapy Mao HuangYixuan LiuWei Xiong Review 03 January 2024
Extracellular vesicles related gene HSPH1 exerts anti-tumor effects in prostate cancer via promoting the stress response of CD8 + T cells Xinrui WuYinjie ZhuJiahua Pan Brief Report 02 January 2024