Is Monitoring of the Intracellular Active Metabolite Levels of Nucleobase and Nucleoside Analogs Ready for Precision Medicine Applications? Shenjia HuangYicong BianLiyan Miao Review Article 01 August 2022 Pages: 761 - 775
Interchangeability between Generic and Reference Products: Limits of Average Bioequivalence Methodology Philippe Lechat Review Article 19 August 2022 Pages: 777 - 787
Combined Semi-mechanistic Target-Mediated Drug Disposition and Pharmacokinetic–Pharmacodynamic Models of Alirocumab, PCSK9, and Low-Density Lipoprotein Cholesterol in a Pooled Analysis of Randomized Phase I/II/III Studies Patrick NolainNassim DjebliSonia Khier Original Research Article Open access 16 August 2022 Pages: 789 - 802
Results From Drug–Drug Interaction Studies In Vitro and In Vivo Investigating the Inhibitory Effect of Finerenone on the Drug Transporters BCRP, OATP1B1, and OATP1B3 Roland HeinigRobert FrickeStephanie Loewen Original Research Article 27 August 2022 Pages: 803 - 815
Phase 1 Study to Assess the Safety and Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor in Subjects Without Cystic Fibrosis With Moderate Hepatic Impairment Lakshmi ViswanathanEric BachmanPaul Panorchan Original Research Article Open access 29 August 2022 Pages: 817 - 825
Pharmacokinetics of Oral Rebaudioside A in Patients with Type 2 Diabetes Mellitus and Its Effects on Glucose Homeostasis: A Placebo-Controlled Crossover Trial Caroline SimoensKoenraad PhilippaertBart Van der Schueren Original Research Article 03 September 2022 Pages: 827 - 839
Development and Validation of a Length- and Habitus-Based Method of Ideal and Lean Body Weight Estimation for Adults Requiring Urgent Weight-Based Medical Intervention Mike WellsLara Nicole GoldsteinGiles Cattermole Original Research Article 19 September 2022 Pages: 841 - 853
Evaluating Islatravir Administered Via Microneedle Array Patch for Long-Acting HIV Pre-exposure Prophylaxis Using Physiologically Based Pharmacokinetic Modelling Hannah KinvigNicolas CotturaMarco Siccardi Original Research Article Open access 30 September 2022 Pages: 855 - 868
Involvement of Autophagy in the Protective Effects of Ginsenoside Rb1 in a Rat Model of Traumatic Brain Injury Shufeng ZouWei ChenJiugeng Feng Original Research Article 05 October 2022 Pages: 869 - 877
Metabolic Profiling of Glabridin in Rat Plasma, Urine, Bile, and Feces After Intragastric and Intravenous Administration Shundi LiuHao LinXiaojun Cai Original Research Article 15 September 2022 Pages: 879 - 887
Dual Inhibition of CYP3A4 by Voriconazole and Clarithromycin Influences Tacrolimus Pharmacokinetics: Case Series Study Toshinori HiraiKazuko InoTakuya Iwamoto Research Letter 17 August 2022 Pages: 889 - 893