Approaches for Establishing Clinically Relevant Dissolution Specifications for Immediate Release Solid Oral Dosage Forms Andre HermansAndreas M. AbendHaiyan Grady White Paper Open access 22 August 2017 Pages: 1537 - 1549
Recommendations for Selection and Characterization of Protein Biomarker Assay Calibrator Material Kyra J. CowanLakshmi AmaravadiYuda Zhu White Paper Open access 02 October 2017 Pages: 1550 - 1563
Drug Target Interference in Immunogenicity Assays: Recommendations and Mitigation Strategies Zhandong Don ZhongAdrienne Clements-EganManoj Rajadhyaksha White Paper Open access 23 October 2017 Pages: 1564 - 1575
Recommendations for the Assessment and Management of Pre-existing Drug-Reactive Antibodies During Biotherapeutic Development Li XueAdrienne Clements-EganCrystal Sung White Paper Open access 06 November 2017 Pages: 1576 - 1586
How Close Are We to Profiling Immunogenicity Risk Using In Silico Algorithms and In Vitro Methods?: an Industry Perspective Jochem GokemeijerVibha JawaShibani Mitra-Kaushik Commentary 02 October 2017 Pages: 1587 - 1592
In vitro Approaches to Support Bioequivalence and Substitutability of Generic Proton Pump Inhibitors via Nasogastric Tube Administration Ping RenMinglei CuiXiaojian Jiang Commentary 06 September 2017 Pages: 1593 - 1599
Blood–Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies Loqman A. MohamedShashirekha MarkandaiahDavide Trotti Review Article 04 August 2017 Pages: 1600 - 1614
Early to Long-Term Alterations of CNS Barriers After Traumatic Brain Injury: Considerations for Drug Development Beatriz Rodriguez-GrandeAleksandra IchkovaJerome Badaut Review Article 13 September 2017 Pages: 1615 - 1625
New Botanical Anxiolytics for Use in Companion Animals and Humans Rui LiuFida AhmedJohn T. Arnason Review Article 11 September 2017 Pages: 1626 - 1631
Nanotechnology as a Delivery Tool for Precision Cancer Therapies Bhawna SharmaRachael M. CristPavan P. Adiseshaiah Review Article 10 October 2017 Pages: 1632 - 1642
Alternative Splicing: Expanding Diversity in Major ABC and SLC Drug Transporters Ji Eun ParkGongmi RyooWooin Lee Review Article 02 October 2017 Pages: 1643 - 1655
Advancements in Understanding Immunogenicity of Biotherapeutics in the Intraocular Space Eric WakshullValerie QuarmbySwati Gupta Review Article 09 August 2017 Pages: 1656 - 1668
Role of In Vitro Release Methods in Liposomal Formulation Development: Challenges and Regulatory Perspective Deepak SolomonNilesh GuptaVivek Gupta Review Article 18 September 2017 Pages: 1669 - 1681
Mechanistic Fluid Transport Model to Estimate Gastrointestinal Fluid Volume and Its Dynamic Change Over Time Alex YuTrachette JacksonDuxin Sun Research Article 04 October 2017 Pages: 1682 - 1690
Exosomes for the Enhanced Tissue Bioavailability and Efficacy of Curcumin Farrukh AqilRadha MunagalaRamesh Gupta Research Article 18 October 2017 Pages: 1691 - 1702
Dibenzoylmethane Protects Against CCl4-Induced Acute Liver Injury by Activating Nrf2 via JNK, AMPK, and Calcium Signaling Mingnan CaoHuixia WangAh-Ng Kong Research Article 21 August 2017 Pages: 1703 - 1714
Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1 Antari KhotJay TibbittsDhaval K. Shah Research Article 14 August 2017 Pages: 1715 - 1734
Characterization of Apolipoprotein C3 (Apo C3) LNA/DNA Impurities and Degradation Products by LC-MS/MS Olga V. FrieseJustin B. SperryJason C. Rouse Research Article 09 May 2017 Pages: 1735 - 1744
Submicron Matrices Embedded in a Polymeric Caplet for Extended Intravaginal Delivery of Zidovudine Felix MashingaidzeYahya E. ChoonaraViness Pillay Research Article 04 August 2017 Pages: 1745 - 1759
Comparison of NMR and Dynamic Light Scattering for Measuring Diffusion Coefficients of Formulated Insulin: Implications for Particle Size Distribution Measurements in Drug Products Sharadrao M. PatilDavid A. KeireKang Chen Research Article 08 August 2017 Pages: 1760 - 1766
Pharmacokinetics of Mephedrone and Its Metabolites in Human by LC-MS/MS Eulàlia OlestiMagí FarréÓscar J. Pozo Research Article 21 August 2017 Pages: 1767 - 1778
A Flavonoid Glycoside Compound from Murraya paniculata (L.) Interrupts Metastatic Characteristics of A549 Cells by Regulating STAT3/NF-κB/COX-2 and EGFR Signaling Pathways Qing ShiZhou JiangLee Jia Research Article 25 August 2017 Pages: 1779 - 1790
Investigation of the Influence of Protein-Losing Enteropathy on Monoclonal Antibody Pharmacokinetics in Mice Yujie YangTommy R. LiJoseph P. Balthasar Research Article 28 August 2017 Pages: 1791 - 1803
Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach Theodoros PapathanasiouRasmus Vestergaard JuulTrine Meldgaard Lund Research Article 29 August 2017 Pages: 1804 - 1813
Development of an Enantioselective and Biomarker-Informed Translational Population Pharmacokinetic/Pharmacodynamic Model for Etodolac Carolina de Miranda SilvaAdriana RochaJürgen B. Bulitta Research Article 05 September 2017 Pages: 1814 - 1825
Determination of Critical Quality Attributes for a Biotherapeutic in the QbD Paradigm: GCSF as a Case Study Sumit K. SinghDeepak KumarAnurag S. Rathore Research Article 05 September 2017 Pages: 1826 - 1841
Population Pharmacokinetic and Pharmacodynamic Modeling of Artemisinin Resistance in Southeast Asia Jesmin Lohy DasArjen M. DondorpJoel Tarning Research Article Open access 11 September 2017 Pages: 1842 - 1854
siRNA-Mediated RNA Interference in Precision-Cut Tissue Slices Prepared from Mouse Lung and Kidney Mitchel J. R. RuigrokNalinie MagganWouter L. J. Hinrichs Research Article Open access 11 September 2017 Pages: 1855 - 1863
Investigating Oral Absorption of Carbamazepine in Pediatric Populations Philip KohlmannCordula StillhartNeil Parrott Research Article 02 October 2017 Pages: 1864 - 1877
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Clearance and Liver Partitioning of OATP and OCT Substrates in Cynomolgus Monkeys Bridget L. MorseJamus G. MacGuireYurong Lai Research Article 10 October 2017 Pages: 1878 - 1889