PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model Ching-Chi ChiuChin-Song LuHung-Li Wang OriginalPaper 08 August 2018 Pages: 3835 - 3853
Kinesins: Motor Proteins as Novel Target for the Treatment of Chronic Pain P. A. ShantanuDilip SharmaVinod Tiwari ReviewPaper 13 September 2018 Pages: 3854 - 3864
Molecular Association of Glia Maturation Factor with the Autophagic Machinery in Rat Dopaminergic Neurons: a Role for Endoplasmic Reticulum Stress and MAPK Activation Govindhasamy Pushpavathi SelvakumarShankar S IyerAsgar Zaheer OriginalPaper 14 September 2018 Pages: 3865 - 3881
Choline Rescues Behavioural Deficits in a Mouse Model of Rett Syndrome by Modulating Neuronal Plasticity Eunice W. M. ChinWee Meng LimEyleen L. K. Goh OriginalPaper Open access 15 September 2018 Pages: 3882 - 3896
Sprouty2—a Novel Therapeutic Target in the Nervous System? Barbara HausottLars Klimaschewski ReviewPaper Open access 17 September 2018 Pages: 3897 - 3903
Fragile X and APP: a Decade in Review, a Vision for the Future Cara J. Westmark ReviewPaper 17 September 2018 Pages: 3904 - 3921
Amyloid β Peptide Compromises Neural Stem Cell Fate by Irreversibly Disturbing Mitochondrial Oxidative State and Blocking Mitochondrial Biogenesis and Dynamics Maria Filipe RibeiroTânia GenebraSusana Solá OriginalPaper 18 September 2018 Pages: 3922 - 3936
Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury M. LanzaM. CampoloEmanuela Esposito OriginalPaper 18 September 2018 Pages: 3937 - 3947
Diltiazem Promotes Regenerative Axon Growth Eric A. HuebnerStéphane BudelClifford J. Woolf OriginalPaper 19 September 2018 Pages: 3948 - 3957
Alterations in the Serotonin and Dopamine Pathways by Cystathionine Beta Synthase Overexpression in Murine Brain J. LondonF. K. NdiayeC. Rouch OriginalPaper 20 September 2018 Pages: 3958 - 3971
Modeling Alzheimer’s Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation Kuo-Hsuan ChangGuey-Jen Lee-ChenChiung-Mei Chen OriginalPaper Open access 20 September 2018 Pages: 3972 - 3983
Visualization of the Breakdown of the Axonal Transport Machinery: a Comparative Ultrastructural and Immunohistochemical Approach Sebastian RühlingFranziska KramerTanja Hochstrasser OriginalPaper 21 September 2018 Pages: 3984 - 3998
Myelin Water Fraction Imaging Reveals Hemispheric Asymmetries in Human White Matter That Are Associated with Genetic Variation in PLP1 Sebastian OcklenburgCatrona AndersonErhan Genç OriginalPaper 21 September 2018 Pages: 3999 - 4012
The Expression and Cellular Localisation of Neurotrophin and Neural Guidance Molecules in Peritoneal Ectopic Lesions Razan AsallyRobert MarkhamFrank Manconi OriginalPaper 25 September 2018 Pages: 4013 - 4022
Aβ42 Peptide Promotes Proliferation and Gliogenesis in Human Neural Stem Cells A. Bernabeu-ZornozaR. CoronelIsabel Liste OriginalPaper 27 September 2018 Pages: 4023 - 4036
Genetic Knockdown of mGluR5 in Striatal D1R-Containing Neurons Attenuates l-DOPA-Induced Dyskinesia in Aphakia Mice José-Rubén García-MontesOscar SolísRosario Moratalla OriginalPaper 27 September 2018 Pages: 4037 - 4050
Intragenic Transcriptional cis-Antagonism Across SLC6A3 Ying ZhaoJinlong YuZhicheng Lin OriginalPaper 27 September 2018 Pages: 4051 - 4060
Chronic Testosterone Increases Impulsivity and Influences the Transcriptional Activity of the Alpha-2A Adrenergic Receptor Signaling Pathway in Rat Brain Juhee AgrawalBirgit LudwigYogesh Dwivedi OriginalPaper 27 September 2018 Pages: 4061 - 4071
Upregulation of MicroRNA miR-9 Is Associated with Microcephaly and Zika Virus Infection in Mice Haijun ZhangYafei ChangTao Sun OriginalPaper 27 September 2018 Pages: 4072 - 4085
AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress Houssni AbidDorthe CartierIsabelle Lihrmann OriginalPaper 28 September 2018 Pages: 4086 - 4101
Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells Sandhya Prakash KamathAlbert I. Chen OriginalPaper Open access 01 October 2018 Pages: 4102 - 4119
Evidence Supporting a Role for the Blood-Cerebrospinal Fluid Barrier Transporting Circulating Ghrelin into the Brain Maia UriartePablo Nicolás De FrancescoMario Perello OriginalPaper 02 October 2018 Pages: 4120 - 4134
Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain Meritxell Llorca-TorralbaFuencisla Pilar-CuéllarEsther Berrocoso OriginalPaper 03 October 2018 Pages: 4135 - 4150
Neuron-Type Specific Loss of CDKL5 Leads to Alterations in mTOR Signaling and Synaptic Markers Ethan SchroederLi YuanJyothi Arikkath OriginalPaper 04 October 2018 Pages: 4151 - 4162
Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses Samuel KohtalaWiebke TheilmannTomi Rantamäki OriginalPaper Open access 04 October 2018 Pages: 4163 - 4174
Early Manifestations of Brain Aging in Mice Due to Low Dietary Folate and Mild MTHFR Deficiency Renata H. BahousMarta Cosín-TomásRima Rozen OriginalPaper 04 October 2018 Pages: 4175 - 4191
Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation Ji-Hong MoonJae-Kyo JeongSang-Youel Park OriginalPaper 05 October 2018 Pages: 4192 - 4202
Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System Yoichiro ShinoharaAyumu KonnoHirokazu Hirai OriginalPaper 05 October 2018 Pages: 4203 - 4214
Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice Tamara HeermannLillian GarrettSabine M. Hölter OriginalPaper 06 October 2018 Pages: 4215 - 4230
Mechanical Stretch of High Magnitude Provokes Axonal Injury, Elongation of Paranodal Junctions, and Signaling Alterations in Oligodendrocytes Elena ChiertoAnne SimonMehrnaz Jafarian-Tehrani OriginalPaper Open access 08 October 2018 Pages: 4231 - 4248
Immunosignature Analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Oliver P. GüntherJennifer L. GardyDavid M. Patrick OriginalPaper Open access 08 October 2018 Pages: 4249 - 4257
Methamphetamine (MA) Use Induces Specific Changes in LINE-1 Partial Methylation Patterns, Which Are Associated with MA-Induced Paranoia: a Multivariate and Neuronal Network Study Rasmon KalayasiriKorakot KraijakApiwat Mutirangura OriginalPaper 09 October 2018 Pages: 4258 - 4272
Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo Patrick Piero BovioHenriette FranzTanja Vogel OriginalPaper Open access 10 October 2018 Pages: 4273 - 4287
Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma Antonio InserraClaudio Alberto MastronardiMa-Li Wong ReviewPaper Open access 10 October 2018 Pages: 4288 - 4305
PDE3 Inhibitors Repurposed as Treatments for Age-Related Cognitive Impairment Shuichi YanaiShogo Endo ReviewPaper 11 October 2018 Pages: 4306 - 4316
Absence of Mutation Enrichment for Genes Phylogenetically Conserved in the Olivocerebellar Motor Circuitry in a Cohort of Canadian Essential Tremor Cases Jean-François SchmouthGabrielle HouleGuy A. Rouleau OriginalPaper 12 October 2018 Pages: 4317 - 4321
Heterozygous Meg2 Ablation Causes Intraocular Pressure Elevation and Progressive Glaucomatous Neurodegeneration Jacqueline ReinhardSusanne WiemannAndreas Faissner OriginalPaper 12 October 2018 Pages: 4322 - 4345
Bezafibrate Upregulates Mitochondrial Biogenesis and Influence Neural Differentiation of Human-Induced Pluripotent Stem Cells Justyna AugustyniakJacek LenartLeonora Buzanska OriginalPaper Open access 13 October 2018 Pages: 4346 - 4363
Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines Manoj P. DandekarAshwini SaxenaAlbert J. Fenoy OriginalPaper 13 October 2018 Pages: 4364 - 4380
Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice Shigeki MoriguchiSatomi KitaKohji Fukunaga OriginalPaper 15 October 2018 Pages: 4381 - 4394
Astrocyte-Like Cells Differentiated from Dental Pulp Stem Cells Protect Dopaminergic Neurons Against 6-Hydroxydopamine Toxicity Kavina GanapathyIndrani DattaRamesh Bhonde OriginalPaper 16 October 2018 Pages: 4395 - 4413
Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice Sandra de la FuenteAlba SansaRosa M. Soler OriginalPaper Open access 16 October 2018 Pages: 4414 - 4427
Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms Lucas Taoro-GonzalezYaiza M. ArenasVicente Felipo OriginalPaper 17 October 2018 Pages: 4428 - 4439
The Epigenetic Factor CBP Is Required for the Differentiation and Function of Medial Ganglionic Eminence-Derived Interneurons Alejandro Medrano-FernándezJose M. Delgado-GarciaAngel Barco OriginalPaper Open access 17 October 2018 Pages: 4440 - 4454
SNAP25 Gene Polymorphisms Protect Against Parkinson’s Disease and Modulate Disease Severity in Patients Cristina AgliardiFranca Rosa GueriniMario Clerici OriginalPaper 17 October 2018 Pages: 4455 - 4463
Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease Marta Garcia-MirallesNur Amirah Binte Mohammad YusofMahmoud A. Pouladi OriginalPaper 17 October 2018 Pages: 4464 - 4478
The Possibility of an Infectious Etiology of Alzheimer Disease Ghulam M. AshrafVadim V. TarasovGjumrakch Aliev ReviewPaper 18 October 2018 Pages: 4479 - 4491
Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments Courtney R. SullivanCatharine A. MielnikRobert E. McCullumsmith OriginalPaper 18 October 2018 Pages: 4492 - 4517
MAOA-VNTR Genotype Effects on Ventral Striatum-Hippocampus Network in Alzheimer’s Disease: Analysis Using Structural Covariance Network and Correlation with Neurobehavior Performance Hsin-I ChangYa-Ting ChangChiung-Chih Chang OriginalPaper 18 October 2018 Pages: 4518 - 4529
Role of GTPases in the Regulation of Mitochondrial Dynamics in Alzheimer’s Disease and CNS-Related Disorders Athanasios AlexiouGeorgia SoursouGhulam Md Ashraf ReviewPaper 18 October 2018 Pages: 4530 - 4538