Research priorities for measuring biologic age: summary and future directions from the Research Centers Collaborative Network Workshop Tina E. BrinkleyJamie N. JusticeStephen B. Kritchevsky Review Open access 15 October 2022 Pages: 2573 - 2583
Optimising the selection of outcomes for healthy ageing trials: a mixed methods study Muslim Abbas SyedOlalekan Lee AiyegbusiMelanie Calvert Review Open access 17 November 2022 Pages: 2585 - 2609
Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment Marta ZampinoM. Cristina PolidoriLaurence Rubenstein Review Open access 07 July 2022 Pages: 2611 - 2622
Microbiota mitochondria disorders as hubs for early age-related macular degeneration János FehérÁgnes ÉlőIllés Kovács Review Open access 18 August 2022 Pages: 2623 - 2653
The role of age-associated autonomic dysfunction in inflammation and endothelial dysfunction Yunqiu JiangAndriy YabluchanskiyTarun W. Dasari Review 30 June 2022 Pages: 2655 - 2670
DNA methylation trajectories and accelerated epigenetic aging in incident type 2 diabetes Eliza FraszczykChris H. L. ThioMirjam Luijten Original Article 10 August 2022 Pages: 2671 - 2684
Using blood test parameters to define biological age among older adults: association with morbidity and mortality independent of chronological age validated in two separate birth cohorts Johanna DreweliesGizem HueluerIlja Demuth Original Article Open access 24 September 2022 Pages: 2685 - 2699
Old plasma dilution reduces human biological age: a clinical study Daehwan KimDobri D. KiprovIrina M. Conboy Original Article Open access 24 August 2022 Pages: 2701 - 2720
Amyloid \(\upbeta\) (1–42) peptide impairs mitochondrial respiration in primary human brain microvascular endothelial cells: impact of dysglycemia and pre-senescence Siva S. V. P. SakamuriVenkata N. SurePrasad V. G. Katakam Original Article 17 August 2022 Pages: 2721 - 2739
Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions Samuel I. BloomJordan R. TuckerAnthony J. Donato Original Article 09 November 2022 Pages: 2741 - 2755
Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study Roger A. FieldingElizabeth J. AtkinsonNathan K. LeBrasseur Original Article Open access 11 November 2022 Pages: 2757 - 2770
Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults Luca TothAndras CziglerPeter J. Toth OriginalPaper Open access 23 July 2022 Pages: 2771 - 2783
Cognition and brain health among older adults in Iceland: the AGES-Reykjavik study Vaka ValsdóttirBrynja Björk MagnúsdóttirMaría K. Jónsdóttir Original Article 17 August 2022 Pages: 2785 - 2800
Emergence of heartbeat frailty in advanced age I: perspectives from life-long EKG recordings in adult mice Jack M. MoenChristopher H. MorrellEdward G. Lakatta Original Article Open access 27 June 2022 Pages: 2801 - 2830
Increased pulse wave velocity is related to impaired working memory and executive function in older adults with metabolic syndrome Jigar GosaliaPolly S. MontgomeryAndrew W. Gardner Original Article 18 August 2022 Pages: 2831 - 2844
Renoprotective effects of empagliflozin in type 1 and type 2 models of diabetic nephropathy superimposed with hypertension Jan M. WilliamsSydney R. MurphyRichard J. Roman Original Article 29 June 2022 Pages: 2845 - 2861
Unbiased proteomic analysis of extracellular vesicles secreted by senescent human vascular smooth muscle cells reveals their ability to modulate immune cell functions Agata GłuchowskaDominik CysewskiGrażyna Mosieniak Original Article Open access 28 July 2022 Pages: 2863 - 2884
GH deficiency confers protective advantages against Alzheimer’s disease through rescued miRNA expression profile in APP/PS1 mice Sarah NoureddineTatiana SacconMichal M. Masternak Original Article 28 July 2022 Pages: 2885 - 2893
Evolution, epidemiology, geographical distribution, and mutational landscape of newly emerging monkeypox virus Chiranjib ChakrabortyManojit BhattacharyaKuldeep Dhama Original Article 12 September 2022 Pages: 2895 - 2911
Elamipretide effects on the skeletal muscle phosphoproteome in aged female mice Matthew D. CampbellMiguel Martín-PérezDavid Marcinek Original Article Open access 02 November 2022 Pages: 2913 - 2924
Endpoints for geroscience clinical trials: health outcomes, biomarkers, and biologic age Steven R. CummingsStephen B. Kritchevsky Commentary Open access 19 October 2022 Pages: 2925 - 2931