Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET-derived features Ruben P. DörfelJoan M. Arenas-GomezPontus Plavén-Sigray OriginalPaper Open access 26 April 2024
Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Tihamer MolnarAndrea LehoczkiErzsebet Ezer REVIEW Open access 26 April 2024
Prognostic significance of a signature based on senescence-related genes in colorectal cancer Zoltan UngvariAnna UngvariBalázs Győrffy ORIGINAL ARTICLE Open access 25 April 2024
Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats Árpád KovácsSaltanat ZhazykbayevaNazha Hamdani Original Article Open access 24 April 2024
Age-associated B cell infiltration in salivary glands represents a hallmark of Sjögren’s-like disease in aging mice Harini BagavantJustyna DurslewiczUmesh S. Deshmukh ORIGINAL ARTICLE 24 April 2024
Repetitive element transcript accumulation is associated with inflammaging in humans Meghan E. SmithDevin WahlThomas J. LaRocca ORIGINAL ARTICLE 20 April 2024
How does a fly die? Insights into ageing from the pathophysiology of Drosophila mortality Eliano dos SantosHelena M. Cochemé REVIEW ARTICLE Open access 20 April 2024
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages Anna CsiszarAnna UngvariZoltan Ungvari REVIEW Open access 19 April 2024
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride Nisi JiangJonathan GelfondJames F. Nelson ORIGINAL ARTICLE Open access 17 April 2024
NASH triggers cardiometabolic HFpEF in aging mice Dániel KucseraMihály RuppertZoltán V. Varga ORIGINAL ARTICLE Open access 17 April 2024
Differential mitochondrial bioenergetics and cellular resilience in astrocytes, hepatocytes, and fibroblasts from aging baboons Daniel A. AdekunbiHillary F. HuberAdam B. Salmon ORIGINAL ARTICLE 12 April 2024
Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease Jordan N. WilliamsonShirley A. JamesYuan Yang ORIGINAL ARTICLE 10 April 2024
The association between blood biological age at rehabilitation admission and physical activity during rehabilitation in geriatric inpatients: RESORT Jessica K. LuLihuan GuanAndrea B. Maier ORIGINAL ARTICLE Open access 09 April 2024
Spousal bereavement and its effects on later life physical and cognitive capability: the Tromsø study Bjørn Heine StrandAsta K. HåbergMarijke Veenstra ORIGINAL ARTICLE Open access 09 April 2024
Reduced insulin/IGF-1 signalling upregulates two anti-viral immune pathways, decreases viral load and increases survival under viral infection in C. elegans Elizabeth M. L. DuxburyHanne CarlssonAlexei A. Maklakov ORIGINAL ARTICLE Open access 08 April 2024
Yoga-based lifestyle intervention for healthy ageing in older adults: a two-armed, waitlist randomized controlled trial with multiple primary outcomes Atmakur SnigdhaVijaya MajumdarAmrutha Jose ORIGINAL ARTICLE 07 April 2024
The behavioural effect of short-term cognitive and physical intervention therapies in old dogs Zsófia BognárDóra SzabóEnikő Kubinyi ORIGINAL ARTICLE Open access 03 April 2024
Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging Naibedya DuttaJoe A. GerkeRyo Higuchi-Sanabria Original Article Open access 03 April 2024
DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson’s disease Seong-Jin YuYun WangNigel H. Greig ORIGINAL ARTICLE Open access 02 April 2024
Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine β-synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy Theodora PanagakiLucia JanickovaCsaba Szabo ORIGINAL ARTICLE Open access 01 April 2024
Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model Sara AbudahabMohamad M. KronfolJoseph L. McClay ORIGINAL ARTICLE Open access 01 April 2024
Combined aerobic and strength exercise training on biological ageing in Singaporean breast cancer patients: protocol for the Breast Cancer Exercise Intervention (BREXINT) Pilot Study Patrick Henry Sebastian SitjarSi Ying TanJorming Goh ORIGINAL ARTICLE 28 March 2024
The duration of lithium use and biological ageing: telomere length, frailty, metabolomic age and all-cause mortality Julian MutzWin Lee Edwin WongCathryn M. Lewis ORIGINAL ARTICLE Open access 28 March 2024
Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders Yazhou LiKelli L. VaughanNigel H. Greig ORIGINAL ARTICLE Open access 27 March 2024
A combination nutritional supplement reduces DNA methylation age only in older adults with a raised epigenetic age Kirsty C. McGeeJack SullivanJanet M. Lord ORIGINAL ARTICLE Open access 26 March 2024
A loss of primary cilia by a reduction in mTOR signaling correlates with age-related deteriorations in condylar cartilage Megumi KitamiMasaru KakuTakeyasu Maeda ORIGINAL ARTICLE 25 March 2024
Impact of visceral adipose tissue on longevity and metabolic health: a comparative study of gene expression in perirenal and epididymal fat of Ames dwarf mice Agnieszka ZaczekAndrzej LewińskiAdam Gesing ORIGINAL ARTICLE 22 March 2024
Longitudinal aortic strain, ventriculo-arterial coupling and fatty acid oxidation: novel insights into human cardiovascular aging Hongzhou ZhangShuang LengAngela S. Koh Original Article 22 March 2024
Relationship of psychotropic medication use with physical function among postmenopausal women Hind A. BeydounMay A. BeydounRobert Brunner Original Article Open access 22 March 2024
Age-related decline in cognitive flexibility and inadequate preparation: evidence from task-state network analysis Haishuo XiaTing LiAntao Chen ORIGINAL ARTICLE 22 March 2024
Establishing healthy longevity clinics in publicly funded hospitals Sara L. R. BonnesTzipora StraussAndrea B. Maier Opinion Paper Open access 21 March 2024
Anti-cytomegalovirus antibody levels stratify human immune profiles across the lifespan Makiko WatanabeLisa DavidsonJanko Ž. Nikolich ORIGINAL ARTICLE 21 March 2024
Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice Hongyang XuKatarzyna M. PiekarzHolly Van Remmen ORIGINAL ARTICLE 21 March 2024
Age-related effects on a hierarchical structure of canine cognition Zsófia BognárBorbála TurcsánEnikő Kubinyi ORIGINAL ARTICLE Open access 21 March 2024
Modulation of neural gene networks by estradiol in old rhesus macaque females Rita Cervera-JuanesKip D. ZimmermanHenryk F. Urbanski ORIGINAL ARTICLE Open access 20 March 2024
Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells Ambika VermaGohar AzharJeanne Y. Wei ORIGINAL ARTICLE 20 March 2024
Detecting aortic valve stenosis based on the non-invasive blood pressure waveform—a proof of concept study Eline KhoJimmy SchenkBjorn J. P. van der Ster ORIGINAL ARTICLE Open access 20 March 2024
Dynamics of serum exosome microRNA profile altered by chemically induced estropause and rescued by estrogen therapy in female mice Bianka Machado ZaniniBianca Machado de AvilaAugusto Schneider ORIGINAL ARTICLE 19 March 2024
Di-(2-ethylhexyl) phthalate exposure induces premature testicular senescence by disrupting mitochondrial respiratory chain through STAT5B-mitoSTAT3 in Leydig cell Haiming CaoQigen XieZi Wan ORIGINAL ARTICLE 19 March 2024
RelA-mediated signaling connects adaptation to chronic cardiomyocyte stress with myocardial and systemic inflammation in the ADCY8 model of accelerated aging Vikas KumarKevin Christian BermeaLuigi Adamo ORIGINAL ARTICLE 19 March 2024
Fitness age outperforms body mass index in differentiating aging patterns and health risk profiles of healthy adults aged 51–80 years Manca A.Ventura L.Deriu F. ORIGINAL ARTICLE Open access 18 March 2024
Age-related changes in human brain functional connectivity using graph theory and machine learning techniques in resting-state fMRI data Sepideh BaghernezhadMohammad Reza Daliri ORIGINAL ARTICLE 18 March 2024
Dialysis disequilibrium syndrome in neurosurgery: literature review and illustrative case example Alexander R. EvansXiaochun ZhaoJohn Burke ORIGINAL ARTICLE 15 March 2024
The impact of exercise on blood-based biomarkers of Alzheimer’s disease in cognitively unimpaired older adults Kelsey R. SewellStephanie R. Rainey-SmithBelinda M. Brown ORIGINAL ARTICLE Open access 15 March 2024
Resistance exercise effects on hippocampus subfield volumes and biomarkers of neuroplasticity and neuroinflammation in older adults with low and high risk of mild cognitive impairment: a randomized controlled trial Wouter A. J. VintsJulija ŠeikinaitėNerijus Masiulis ORIGINAL ARTICLE Open access 13 March 2024
The common marmoset as a translational model of age-related osteoarthritis Dennis M. MintonAditya R. AilianiAdam R. Konopka ORIGINAL ARTICLE 11 March 2024 Pages: 2827 - 2847
Endothelial specific prolyl hydroxylase domain-containing protein 2 deficiency attenuates aging-related obesity and exercise intolerance Lihong PanXiaochen HeYingjie Chen ORIGINAL ARTICLE Open access 11 March 2024
DNA methylation-based estimators of telomere length show low correspondence with paternal age at conception and other measures of external validity of telomere length Dan T. A. EisenbergCalen P. RyanChristopher Kuzawa ORIGINAL ARTICLE 11 March 2024
Mitochondrial disorders leading to Alzheimer’s disease—perspectives of diagnosis and treatment Magdalena PszczołowskaKamil WalczakJerzy Leszek REVIEW Open access 08 March 2024 Pages: 2977 - 2988
