Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study Masashi MorifujiSeiichiro HigashiMasashi Nagata ORIGINAL ARTICLE 24 May 2024
Fmo induction as a tool to screen for pro-longevity drugs Shijiao HuangRebecca L. CoxScott F. Leiser ORIGINAL ARTICLE 24 May 2024
Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons Celine CamonMel PrescottMichael Garratt ORIGINAL ARTICLE Open access 22 May 2024
Carotid-femoral pulse wave velocity score, an estimator of cognitive performance in the elderly: results from the Toledo Study for Healthy Aging Fabio A. Quiñónez BareiroJosé A. CarniceroFrancisco J. García García ORIGINAL ARTICLE 22 May 2024
EEG entropy insights in the context of physiological aging and Alzheimer’s and Parkinson’s diseases: a comprehensive review Alessia CacciottiChiara PappaletteraFabrizio Vecchio REVIEW 22 May 2024
Optimizing cardiopulmonary rehabilitation duration for long COVID patients: an exercise physiology monitoring approach Zsofia SzarvasMonika FeketeJanos Tamas Varga ORIGINAL ARTICLE Open access 21 May 2024
Five years later, with double the demographic data, naked mole-rat mortality rates continue to defy Gompertzian laws by not increasing with age J. Graham RubyMegan SmithRochelle Buffenstein Original Article Open access 21 May 2024
Hepatic WDR23 proteostasis mediates insulin homeostasis by regulating insulin-degrading enzyme capacity Chatrawee DuangjanThalida Em ArpawongSean P. Curran ORIGINAL ARTICLE Open access 20 May 2024
Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis Jack Donato RockholdHeather MarszalkowskiLeena P. Bharath ORIGINAL ARTICLE 18 May 2024
Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging Alan E. WoessnerNathan J. WittKyle P. Quinn Original Article Open access 18 May 2024
Quantification of healthspan in aging mice: introducing FAMY and GRAIL Dudley W. Lamming METHODS PAPER 17 May 2024
Amyloid β accelerates age-related proteome-wide protein insolubility Edward AndertonManish ChamoliGordon J. Lithgow ORIGINAL ARTICLE Open access 16 May 2024
Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin Richard A. MillerDavid E. HarrisonRandy Strong ORIGINAL ARTICLE 16 May 2024
Clinical biomarker-based biological age predicts deaths in Brazilian adults: the ELSA-Brasil study Amanda Viana MachadoJuliana Freitas de Mello e SilvaSandhi Maria Barreto ORIGINAL ARTICLE 16 May 2024
A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple aging pathways Zhou JiangQianpei HeWarren Ladiges ORIGINAL ARTICLE Open access 16 May 2024
Neuroanatomical substrates of depression in dementia with Lewy bodies and Alzheimer’s disease Manon QuerryAnne BotzungFrédéric Blanc ORIGINAL ARTICLE 15 May 2024
Multi-night acoustic stimulation is associated with better sleep, amyloid dynamics, and memory in older adults with cognitive impairment Céline J. ZellerMarina WunderlinStefan Klöppel ORIGINAL ARTICLE Open access 14 May 2024
Reliable detection of stochastic epigenetic mutations and associations with cardiovascular aging Yaroslav MarkovMorgan LevineAlbert T. Higgins-Chen ORIGINAL ARTICLE 13 May 2024
Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer’s-like pathological dementia Kumar VaibhavMayuri GulhaneFernando L. Vale ORIGINAL ARTICLE 11 May 2024
Young blood-mediated cerebromicrovascular rejuvenation through heterochronic parabiosis: enhancing blood-brain barrier integrity and capillarization in the aged mouse brain Rafal GulejÁdám Nyúl-TóthZoltan Ungvari ORIGINAL ARTICLE 10 May 2024
Abnormal EEG microstates in Alzheimer’s disease: predictors of β-amyloid deposition degree and disease classification Yibing YanManman GaoKai Wang ORIGINAL ARTICLE Open access 10 May 2024
The influence of immobility on muscle loss in older people with frailty and fragility fractures Eleanor K. LuntAdam L. GordonJohn F. R. Gladman ORIGINAL ARTICLE Open access 10 May 2024
Association between physical fitness and executive functions in cognitively healthy female older adults: a cross-sectional study Shirko AhmadiIsadora QuirionSaid Mekari ORIGINAL ARTICLE 09 May 2024
Intensive antihypertensive treatment does not lower cerebral blood flow or cause orthostatic hypotension in frail older adults Ralf W. J. WeijsBente M. de RoosJurgen A. H. R. Claassen ORIGINAL ARTICLE Open access 09 May 2024
Genome integrity as a potential index of longevity in Ashkenazi Centenarian’s families Mariana AndrawusGil Ben DavidGil Atzmon ORIGINAL ARTICLE Open access 09 May 2024
Sex-specific relationships of inflammatory biomarkers with blood pressure in older adults Joanna Sulicka-GrodzickaBarbara WiznerTomasz J. Guzik ORIGINAL ARTICLE Open access 08 May 2024
Age-related shifts in mental health determinants from a deprived area in the European Union: informing the national healthy aging program of Hungary Nora KovacsEva BiroRoza Adany ORIGINAL ARTICLE Open access 07 May 2024
Hemodynamic gain index and risk of chronic kidney disease: A prospective cohort study of middle-aged and older men Setor K. KunutsorJari A. Laukkanen SHORT COMMUNICATION Open access 06 May 2024
Evaluating osteoporosis and bone quality in the aging spine: modern considerations for surgical management in the geriatric population Miles HudsonJenna MeyerJoshua Bakhsheshian REVIEW 04 May 2024
Trends in prevalence, mortality, and risk factors of dementia among the oldest-old adults in the United States: the role of the obesity epidemic Xueshan CaoMinmin WangYang Guo ORIGINAL ARTICLE 02 May 2024
Using non-invasive behavioral and physiological data to measure biological age in wild baboons Chelsea J. WeibelMauna R. DasariElizabeth A. Archie ORIGINAL ARTICLE Open access 02 May 2024
Cannabinoids and healthy ageing: the potential for extending healthspan and lifespan in preclinical models with an emphasis on Caenorhabditis elegans Zhizhen WangJonathon C. Arnold REVIEW Open access 02 May 2024
Newer treatment paradigm improves outcomes in the most common neurosurgical disease of the elderly: a literature review of middle meningeal artery embolization for chronic subdural hematoma Luca H. DebsSamantha E. WalkerScott Y. Rahimi REVIEW Open access 01 May 2024
Echocardiographic characterization of age- and sex-associated differences in cardiac function and morphometry in nonhuman primates Maria Cristina FlorioLaura FusiniMaurizio C. Capogrossi ORIGINAL ARTICLE 30 April 2024
Autopsy findings in cancer patients infected with SARS-CoV-2 show a milder presentation of COVID-19 compared to non-cancer patients Éva KocsmárIldikó KocsmárGábor Lotz ORIGINAL ARTICLE Open access 30 April 2024
Increases in regional brain volume across two native South American male populations Nikhil N. ChaudhariPhoebe E. ImmsAndrei Irimia ORIGINAL ARTICLE Open access 29 April 2024
Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET-derived features Ruben P. DörfelJoan M. Arenas-GomezPontus Plavén-Sigray OriginalPaper Open access 26 April 2024
Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Tihamer MolnarAndrea LehoczkiErzsebet Ezer REVIEW Open access 26 April 2024
Prognostic significance of a signature based on senescence-related genes in colorectal cancer Zoltan UngvariAnna UngvariBalázs Győrffy ORIGINAL ARTICLE Open access 25 April 2024
Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats Árpád KovácsSaltanat ZhazykbayevaNazha Hamdani Original Article Open access 24 April 2024
Age-associated B cell infiltration in salivary glands represents a hallmark of Sjögren’s-like disease in aging mice Harini BagavantJustyna DurslewiczUmesh S. Deshmukh ORIGINAL ARTICLE 24 April 2024
Repetitive element transcript accumulation is associated with inflammaging in humans Meghan E. SmithDevin WahlThomas J. LaRocca ORIGINAL ARTICLE 20 April 2024
How does a fly die? Insights into ageing from the pathophysiology of Drosophila mortality Eliano dos SantosHelena M. Cochemé REVIEW ARTICLE Open access 20 April 2024
Atherosclerotic burden and cerebral small vessel disease: exploring the link through microvascular aging and cerebral microhemorrhages Anna CsiszarAnna UngvariZoltan Ungvari REVIEW Open access 19 April 2024
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride Nisi JiangJonathan GelfondJames F. Nelson ORIGINAL ARTICLE Open access 17 April 2024
NASH triggers cardiometabolic HFpEF in aging mice Dániel KucseraMihály RuppertZoltán V. Varga ORIGINAL ARTICLE Open access 17 April 2024
Differential mitochondrial bioenergetics and cellular resilience in astrocytes, hepatocytes, and fibroblasts from aging baboons Daniel A. AdekunbiHillary F. HuberAdam B. Salmon ORIGINAL ARTICLE 12 April 2024
Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease Jordan N. WilliamsonShirley A. JamesYuan Yang ORIGINAL ARTICLE 10 April 2024
The association between blood biological age at rehabilitation admission and physical activity during rehabilitation in geriatric inpatients: RESORT Jessica K. LuLihuan GuanAndrea B. Maier ORIGINAL ARTICLE Open access 09 April 2024
Spousal bereavement and its effects on later life physical and cognitive capability: the Tromsø study Bjørn Heine StrandAsta K. HåbergMarijke Veenstra ORIGINAL ARTICLE Open access 09 April 2024