Development of Delta Opioid Peptides as Nonaddicting Analgesics Rao S. RapakaFrank Porreca ReviewPaper Pages: 1 - 8
The Effect of Parenterally Administered Cyclodextrins on Cholesterol Levels in the Rat Henderik W. FrijlinkAnko C. EissensDirk K. F. Meijer OriginalPaper Pages: 9 - 16
Terpenes and the Lipid–Protein–Partitioning Theory of Skin Penetration Enhancement Adrian C. WilliamsBrian W. Barry OriginalPaper Pages: 17 - 24
The Role of Metabolites in Bioequivalency Assessment. I. Linear Pharmacokinetics without First-Pass Effect Mei-Ling ChenAndré J. Jackson OriginalPaper Pages: 25 - 32
Quantification of Imipenem’s Primary Metabolite in Plasma by Postcolumn Chemical Rearrangement and UV Detection Donald G. MussonRichard HajduJohn D. Rogers OriginalPaper Pages: 33 - 39
Absorption and Disposition of Colloidal Drug Delivery Systems. I. High-Performance Liquid Chromatographic (HPLC) Analysis of a Cyclosporin Emulsion Susan J. CorvariR. Gary HollenbeckDavid Young OriginalPaper Pages: 40 - 42
Quantitative Structure–Activity Relationships (QSARs) of Pyrimidine Nucleosides as HIV-1 Antiviral Agents Massoud Mahmoudian OriginalPaper Pages: 43 - 46
Optimization of Spray-Dried and -Congealed Lipid Micropellets and Characterization of Their Surface Morphology by Scanning Electron Microscopy Türkan EldemPeter SpeiserAtilla Hincal OriginalPaper Pages: 47 - 54
In Vitro Release of Hydrocortisone from Topical Preparations and Automated Procedure Vinod P. ShahJerome ElkinsJerome P. Skelly OriginalPaper Pages: 55 - 59
Enhanced Bioavailability of Subcutaneously Injected Insulin by Pretreatment with Ointment Containing Protease Inhibitors Masaharu TakeyamaToshihiko IshidaRyohei Hori OriginalPaper Pages: 60 - 64
Role of Complements C3 and C5 in the Phagocytosis of Liposomes by Human Neutrophils Jeffrey F. ScieszkaLinda L. MaggioraM. J. Cho OriginalPaper Pages: 65 - 69
A Comparison of Peptidase Activities and Peptide Metabolism in Cultured Mouse Keratinocytes and Neonatal Mouse Epidermis Praful K. ShahRonald T. Borchardt OriginalPaper Pages: 70 - 75
Studies in Phlebitis: Detection and Quantitation Using a Thermographic Camera Gary H. WardPaul E. Nolan JrSamuel H. Yalkowsky OriginalPaper Pages: 76 - 79
Precipitation of the Renin Inhibitor Ditekiren Upon iv Infusion; in Vitro Studies and Their Relationship to in Vivo Precipitation in the Cynomolgus Monkey Stephen R. DavioMargaret M. McShaneSerena L. Cole OriginalPaper Pages: 80 - 83
Relationship Between Drug Absorption Enhancing Activity and Membrane Perturbing Effects of Acylcarnitines Edward L. LeCluyseLeah E. AppelSteven C. Sutton OriginalPaper Pages: 84 - 87
The Solubility-Modulated Osmotic Pump: In Vitro/in Vivo Release of Diltiazem Hydrochloride Gregory A. McClellandSteven C. SuttonGaylen M. Zentner OriginalPaper Pages: 88 - 92
Oral Absorption of Peptides: Influence of pH and Inhibitors on the Intestinal Hydrolysis of Leu-Enkephalin and Analogues Doron I. FriedmanGordon L. Amidon OriginalPaper Pages: 93 - 96
Mechanism of Gastric Emptying of a Nondisintegrating Radiotelemetry Capsule in Man Parviz MojaverianJames C. ReynoldsPeter H. Vlasses OriginalPaper Pages: 97 - 100
Jejunal Absorption, Pharmacological Activity, and Pharmacokinetic Evaluation of Indomethacin-Loaded Poly(d,l-Lactide) and Poly(Isobutyl-Cyanoacrylate) Nanocapsules in Rats Nazih AmmouryHatem FessiSimon Benita OriginalPaper Pages: 101 - 105
Thermal Injury Decreases Hepatic Blood Flow and the Intrinsic Clearance of Indocyanine Green in the Rat Gary M. PollackKim L. R. Brouwer OriginalPaper Pages: 106 - 111
Dose-Dependent Pharmacokinetics of the Aldose Reductase Inhibitor Imirestat in Man R. Kim BrazzellPhilip R. MayerJohn T. Slattery OriginalPaper Pages: 112 - 118
Structural Confirmation of Ampicillin Polymers Formed in Aqueous Solution Hatsumi AkiNobuyoshi SawaiMagobei Yamamoto Note Pages: 119 - 122
Examination of Arrhenius Kinetics for an Antiarrhythmic Compound Tugrul T. KararliThomas CatalanoRichard M. Bittman Note Pages: 123 - 126
The Effects Of Hemodilution, pH, and Protamine on Lidocaine Plasma Protein Binding and Red Blood-Cell Uptake in Vitro Rory P. RemmelAlan K. CopaDavid M. Angaran Note Pages: 127 - 130
Self-Release of Lipase from Compacts Materials M. Hossein ZarrintanMichael J. Groves Note Pages: 131 - 133
Intranasal Delivery of RS-93522, a Dihydropyridine-Type Calcium-Channel Antagonist Roger Cherng-Chi FuJohn L. WhatleyJeffrey S. Fleitman Note Pages: 134 - 135
Consensus Report on "Issues in the Evaluation of Bioavailability" Iain J. McGilveray Legacy Pages: 136 - 138