Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review Amitava MitraYaning Wang Perspective 05 July 2022 Pages: 1663 - 1667
Review: Role of Model-Informed Drug Development Approaches in the Lifecycle of Drug Development and Regulatory Decision-Making Rajanikanth MadabushiPaul SeoHao Zhu Review Article 12 May 2022 Pages: 1669 - 1680
The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives Om AnandXavier J. H. PepinPaul Seo Review Article 18 May 2022 Pages: 1681 - 1700
Applications, Challenges, and Outlook for PBPK Modeling and Simulation: A Regulatory, Industrial and Academic Perspective Wen LinYuan ChenTycho Heimbach Review Article 13 May 2022 Pages: 1701 - 1731
Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom? Sebastian FrechenAmin Rostami-Hodjegan White Paper Open access 20 April 2022 Pages: 1733 - 1748
Pharmacokinetic and Pharmacodynamic Modeling of siRNA Therapeutics – a Minireview Jae Yoon JeonVivaswath S. AyyarAmitava Mitra Review Article 12 July 2022 Pages: 1749 - 1759
Applications of Model-Based Meta-Analysis in Drug Development Phyllis ChanKirill PeskovXuyang Song Original Research Article Open access 16 February 2022 Pages: 1761 - 1777
Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients Carolina Llanos-PaezClaire AmberyMats O. Karlsson Original Research Article Open access 01 March 2022 Pages: 1779 - 1787
Applications of Quantitative Systems Pharmacology (QSP) in Drug Development for NAFLD and NASH and Its Regulatory Application Scott Q. Siler Review Article Open access 24 May 2022 Pages: 1789 - 1802
Role of Disease Progression Models in Drug Development Jeffrey S. BarrettTim NicholasBrian W. Corrigan Original Research Article 11 April 2022 Pages: 1803 - 1815
Dose Finding in Oncology: What is Impeding Coming of Age? Kapil MayawalaDinesh de Alwis Perspective Open access 26 April 2022 Pages: 1817 - 1822
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics Silvia Moreno-MendietaDaniel GuillénRomina Rodríguez-Sanoja Review Article 23 June 2022 Pages: 1823 - 1849
RETRACTED ARTICLE: Dual Blockade of PD-1 and LAG3 Immune Checkpoints Increases Dendritic Cell Vaccine Mediated T Cell Responses in Breast Cancer Model Asal BarshidiVahid KarpishehFarhad Jadidi-Niaragh Research Paper 17 June 2022 Pages: 1851 - 1866
Mechanistic Modeling of the Effect of Recombinant Human Hyaluronidase (rHuPH20) on Subcutaneous Delivery of Cetuximab in Rats Xizhe GaoJongbong LeeLeonid Kagan Original Research Article 01 July 2022 Pages: 1867 - 1880
Lack of an Effect of Polysorbate 80 on Intestinal Drug Permeability in Humans Melissa MetrySamuel A. KrugJames E. Polli Original Research Article 08 June 2022 Pages: 1881 - 1890
Design and Development of a New Glucagon-Like Peptide-1 Receptor Agonist to Obtain High Oral Bioavailability Hao ChenYun LuJianping Liu Original Research Article 13 June 2022 Pages: 1891 - 1906
Population Pharmacokinetic Evaluation with External Validation of Tacrolimus in Chinese Primary Nephrotic Syndrome Patients Lin YangNan YangZhijun Huang Original Research Article 01 June 2022 Pages: 1907 - 1920
Development of Physiology Based Pharmacokinetic Model to Predict the Drug Interactions of Voriconazole and Venetoclax Ji DongShuai-bing LiuLi-yan Miao Original Research Article 21 June 2022 Pages: 1921 - 1933
In-Vivo Tape Stripping Study with Caffeine for Comparisons on Body Sites, Age and Washing William WargniezSophie ConnétableSébastien Grégoire Original Research Article 21 June 2022 Pages: 1935 - 1944
Microneedle-Mediated Permeation Enhancement of Chlorhexidine Digluconate: Mechanistic Insights Through Imaging Mass Spectrometry Melissa KirkbyAkmal Bin SabriGary Moss Original Research Article Open access 10 June 2022 Pages: 1945 - 1958
Investigation of an Uncommon Artifact during Reducing Capillary Electrophoresis-Sodium Dodecyl Sulfate Analysis of a Monoclonal Antibody with Dynamic Light Scattering and Reversed Phase High-Performance Liquid Chromatography Han GaoSi-Tao WangWei-Jie Fang Original Research Article 14 June 2022 Pages: 1959 - 1968
Correction to: Liposomal Formulation for Oral Delivery of Cyclosporine A: Usefulness as a Semisolid-Dispersion System Keiko MinamiMakoto KataokaShinji Yamashita Correction 10 June 2022 Pages: 1969 - 1969