Integrated network pharmacology analysis and experimental validation to investigate the mechanism of Flavan-3-ols and aromatic resins in depression Ansari Vikhar Danish AhmadSubur W. KhanQazi Yasar Original Article 29 May 2024
SHARPIN contributes to sevoflurane-induced neonatal neurotoxicity through up-regulating HMGB1 to repress M2 like-macrophage polarization Junying CaiYue LinJun Lu Original Article 28 May 2024
Berberine improves cognitive impairment by alleviating brain atrophy and promoting white matter reorganization in diabetic db/db mice: a magnetic resonance imaging-based study Xin-yu YangChun-jing YangMan-zhong Li Research 27 May 2024
Plasma water T2 detects age-stratified differences in cardiometabolic health among familial CCM patients with Hispanic CCM1 mutation Jacob CroftDiana F. SandovalJun Zhang Original Article 25 May 2024
Aconitum coreanum and processed products on its base prevent stroke via the PI3K/Akt and KEAP1/NRF2 in the in vivo study Wan-ting ZengLi-ting ZhouYang Qu Original Article 25 May 2024
Genistein mitigates nitroglycerine-induced migraine: modulation of nitric oxide-mediated vasodilation and oxidative stress Sarika ChaudharyLovedeep SinghPankaj Kadyan Original Article 25 May 2024
Biochemical and molecular analysis of pediatric patients with metachromatic leukodystrophy in South China: functional characterization of five novel ARSA variants Taolin LiYonglan HuangWen Zhang Original Article 22 May 2024
Hsa_circ_0004872 mitigates proliferation, metastasis and immune escape of meningioma cells by suppressing PD-L1 Kuo ChenZhengming HuangYongkai Huang Original Article Open access 21 May 2024
High salt diet induces cognitive impairment and is linked to the activation of IGF1R/mTOR/p70S6K signaling Shu LiuXu YangZhiyou Cai Original Article 21 May 2024
Association between insulin resistance and multiple sclerosis: a systematic review and meta-analysis Mahdi SepidarkishNarges KalantariHoda Shirafkan Review Article 20 May 2024
Anti-inflammatory, antioxidant and anti-mitophagy effects of trans sodium crocetinate on experimental autoimmune encephalomyelitis in BALB/C57 mice Sara BanaeeyehAmir Afkhami-GoliHossein Hosseinzadeh Original Article 13 May 2024
Label free quantitative proteomic profiling of serum samples of intellectually disabled young patients revealed dysregulation of complement coagulation and cholesterol cascade systems Soma VankwaniMunazza Raza MirzaMuhammad Iqbal Choudhary Original Article 11 May 2024
Berberine attenuates brain aging via stabilizing redox homeostasis and inflammation in an accelerated senescence model of Wistar rats Arun Kumar YadawaParisha SrivastavaSyed Ibrahim Rizvi Original Article 10 May 2024
High sugar consumption for seven days in adult mice increased blood glucose variability, induced an anxiolytic effect and triggered oxidative stress in cerebral cortex Asma Lahouel Original Article 09 May 2024
The role of SKA2 on affective disorder, post-traumatic stress disorder and suicide behavior: systematic review and in silico analysis Thelma Beatriz González-CastroItzel RodrÃguez-FuentesJorge Luis Hernández-Vicencio Review Article 09 May 2024
Ferulago Angulata methanolic extract ameliorates scopolamine-induced memory impairment through the inhibition of hippocampal monoamine oxidase activity Samaneh hajimohammadiMaliheh SoodiNiloofar Mashhadi sharif Original Article 09 May 2024
Glioma hexokinase 3 positively correlates with malignancy and macrophage infiltration Tingyu LiangXingang ZhouWenbin Ma Original Article 30 April 2024
Curcumin attenuates brain aging by reducing apoptosis and oxidative stress Mehran CherikiMasoumeh HabibianSeyyed Jafar Moosavi Original Article 30 April 2024
Nutritional strategies cause memory damage and alter biochemical parameters without causing neuroinflammation Keila Rufatto de SouzaNicole Alessandra EngelGislaine Tezza Rezin Original Article 02 March 2024 Pages: 635 - 648
Methylseleninic acid inhibits human glioma growth in vitro and in vivo by triggering ROS-dependent oxidative damage and apoptosis Wang ChenPida HaoXianjun Wang Original Article 28 February 2024 Pages: 625 - 633
Molecular and in silico investigation of a novel ECHS1 gene mutation in a consanguine family with short-chain enoyl-CoA hydratase deficiency and Mt-DNA depletion: effect on trimer assembly and catalytic activity Marwa MaalejLamia SfaihiFaiza Fakhfakh Original Article 16 February 2024 Pages: 611 - 623
New curcumin-loaded nanocapsules as a therapeutic alternative in an amnesia model Karline da Costa RodriguesManoel Rodrigues da Silva NetoCristiane Luchese Original Article 14 February 2024 Pages: 589 - 609
Identification of metabolic pathways and key genes associated with atypical parkinsonism using a systems biology approach Amanda PasqualottoVinÃcius da SilvaMarina Siebert Original Article 02 February 2024 Pages: 577 - 587
Etomidate inhibits tumor growth of glioblastoma by regulating M1 macrophage polarization Caiyan GaoYan Nie Original Article 01 February 2024 Pages: 569 - 576
Nuclear translocation of STAT5 initiates iron overload in huntington’s disease by up-regulating IRP1 expression Li NiuYongze ZhouWei Zeng Original Article 23 January 2024 Pages: 559 - 567
A computational approach to analyzing the functional and structural impacts of Tripeptidyl-Peptidase 1 missense mutations in neuronal ceroid lipofuscinosis Priyanka KPriya N MadhanaMagesh Ramasamy Original Article 08 January 2024 Pages: 545 - 558
Therapeutic efficacy and pharmacological mechanism of Yindan Xinnaotong soft capsule on acute ischemic stroke: a meta-analysis and network pharmacology analysis Fangjie YangXinmin LiYasu Zhang Original Article 29 December 2023 Pages: 523 - 543
Genomic insights and advanced machine learning: characterizing autism spectrum disorder biomarkers and genetic interactions Laila Dabab NahasAnkur DattaHatem Zayed Original Article Open access 28 December 2023 Pages: 29 - 42
Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin Khaled G. Abdel-WahhabRehab S. SayedFathia A. Mannaa Original Article Open access 27 December 2023 Pages: 101 - 113
Molecular dynamics exploration of Lupenone: therapeutic implications for glioblastoma multiforme and alzheimer's amyloid beta pathogenesis Hailah M. AlmohaimeedAmany I. AlmarsMona H. Soliman Original Article 22 December 2023 Pages: 77 - 88
Hesperidin counteracts chlorpyrifos-induced neurotoxicity by regulating oxidative stress, inflammation, and apoptosis in rats Sefa KüçüklerCuneyt CaglayanFatih Mehmet Kandemir Original Article 18 December 2023 Pages: 509 - 522
Considerations for Chinese tolerable upper intake level for selenium Jia-Meng LiYa-Zhi BaiShuang-Qing Zhang Commentary 16 December 2023 Pages: 485 - 486
NMR based Serum metabolomics revealed metabolic signatures associated with oxidative stress and mitochondrial damage in brain stroke Sachin YadavAbhai KumarDinesh Kumar Original Article 14 December 2023 Pages: 283 - 294
Circ_0027446 promotes malignant development of glioblastoma by interacting with miR-346 to up-regulate PGK1 Zifeng CaiYonghui CaiJinning Zhang Original Article 13 December 2023 Pages: 361 - 371
Chitosan/PLA-loaded Magnesium oxide nanocomposite to attenuate oxidative stress, neuroinflammation and neurotoxicity in rat models of Alzheimer's disease Manickam RajkumarPrabha GovindarajSoundarapandian Kannan Original Article 12 December 2023 Pages: 487 - 508
Development of novel treatments for amyotrophic lateral sclerosis Zhuo SunBo ZhangYing Peng Review Article 11 December 2023 Pages: 467 - 482
Sestrin2 can alleviate endoplasmic reticulum stress to improve traumatic brain injury by activating AMPK/mTORC1 signaling pathway Yu ZhouYong ZhangXuehong Liu Review Article 04 December 2023 Pages: 439 - 452
Proteomics revealed an association between ribosome-associated proteins and amyloid beta deposition in Alzheimer's disease Lina FengGuojun WangMingquan Li Original Article 29 November 2023 Pages: 263 - 282
The role of astrocytes in the glymphatic network: a narrative review Nikita DasRavi DhamijaSumit Sarkar Review Article 27 November 2023 Pages: 453 - 465
Shark fish oil prevents scopolamine-induced memory impairment in an experimental model Sadaf NaeemLiaquat AliAnosh Tahir Original Article 27 November 2023 Pages: 15 - 27
Network pharmacology-based approach to understand the effect and mechanism of chrysophanol against cognitive impairment in Wilson disease Xiao-yan ZhangXie WangDao-jun Xie Original Article 24 November 2023 Pages: 89 - 99
Plasma metabolomics reveals the intervention mechanism of different types of exercise on chronic unpredictable mild stress-induced depression rat model Xiangyu LiuBo ZhangYumei Han OriginalPaper 24 November 2023 Pages: 1 - 13
Combination chemotherapy in rodents: a model for chemotherapy-induced neuropathic pain and pharmacological screening AkhileshAnkit UniyalVinod Tiwari Original Article 22 November 2023 Pages: 43 - 65
Andrographolide inhibits the activation of spinal microglia and ameliorates mechanical allodynia Dan WangYongjian ZhengZhengbing Lv Original Article 18 November 2023 Pages: 115 - 127
Systematic review and meta-analysis of the effects of exercise on cognitive impairment and neuroprotective mechanisms in diabetes mellitus animal models Zhiyao LiuHailiang HuangLiuyang Zhao Original Article 18 November 2023 Pages: 295 - 311
Ginger (Zingiber Officinale Roscoe) ameliorates ethanol-induced cognitive impairment by modulating NMDA and GABA-A receptors in rat hippocampus Jiaojiao WangAbolfazl AkbariJun Wu Original Article 15 November 2023 Pages: 67 - 76
Abnormal expression of long non-coding RNAs RMRP, CTC-487M23.5, and DGCR5 in the peripheral blood of patients with Bipolar disorder Melina GhamariMahdieh Mehrab MohseniZeinab Shirvani-Farsani Original Article 14 November 2023 Pages: 313 - 320
Targeting inflammatory signaling in obsessive compulsive disorder: a promising approach Shvetank BhattKuttiappan AnithaKamal Dua Review Article 11 November 2023 Pages: 335 - 346
Purple pitanga extract (Eugenia uniflora) attenuates oxidative stress induced by MPTP Eduarda Monteiro FidelisAnne Suely P. SavallSimone Pinton Original Article 03 November 2023 Pages: 2615 - 2625
Combining network pharmacology and experimental verification to reveal the mechanism of Chaigui granules in the treatment of depression through PI3K/Akt/mTOR signaling pathways Jun-sheng TianZhen-ning WuXue-mei Qin Original Article 31 October 2023 Pages: 2849 - 2864
