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PdNPs/carbon dots/silica hybrid nanostructures: the development of an electrochemical sensor for simultaneous determination of dopamine and serotonin in real samples

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Abstract

This work describes the synthesis, characterization, and electrochemical application of hybrid PdNPs/carbon dots/silica nanostructures, in which palladium nanoparticles (PdNP) were directly obtained through the carbon dots reduction by only one step. These nanostructures were characterized by UV–vis spectroscopy, FTIR with ATR module, HR-TEM, SEM, AFM, XPS, and electrochemical impedance. A non-enzymatic biosensor was prepared by dispersing the PdNPs/carbon dots/silica nanostructures on a printed carbon electrode, exhibiting excellent electrocatalytic activity for the simultaneous determination of dopamine and serotonin with a detection limit of 36 and 33 nmol L−1, respectively. The detection of dopamine and serotonin was also performed in real samples and did not suffer significant interference from ascorbic acid (AA) or uric acid (UA).

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Acknowledgements

JHA acknowledges CAPES, and T.C.C acknowledges Mackpesquisa, FINEP, CAPES, and CNPq for a Research grant.

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Authors and Affiliations

  1. LabNaHm: Multifunctional Hybrid Nanomaterials Laboratory. Engineering School, Mackenzie Presbyterian University, São Paulo, SP, 01302-907, Brazil

    Joao H. A. Ferreira, Renato M. Peres & Thiago C. Canevari

  2. Institute of Chemistry, University of São Paulo, São Paulo, SP, 05508-000, Brazil

    Marcelo Nakamura & Henrique E. Toma

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  1. Joao H. A. Ferreira
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Correspondence to Thiago C. Canevari.

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Ferreira, J.H.A., Peres, R.M., Nakamura, M. et al. PdNPs/carbon dots/silica hybrid nanostructures: the development of an electrochemical sensor for simultaneous determination of dopamine and serotonin in real samples. J Nanopart Res 25, 9 (2023). https://doi.org/10.1007/s11051-022-05659-1

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