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Biobutanol production from sustainable biomass process of anaerobic ABE fermentation for industrial applications

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Abstract

The growing population increases the need to develop advanced biological methods for utilizing renewable and sustainable resources to produce environmentally friendly biofuels. Currently, energy resources are limited for global demand and are constantly depleting and creating environmental problems. Some higher chain alcohols, like butanol and ethanol, processing similar properties to gasoline, can be alternate sources of biofuel. However, the industrial production of these alcohols remains challenging because they cannot be efficiently produced by microbes naturally. Therefore, butanol is the most interesting biofuel candidate with a higher octane number produced naturally by microbes through Acetone–Butanol–Ethanol fermentation. Feedstock selection as the substrate is the most crucial step in biobutanol production. Lignocellulosic biomass has been widely used to produce cellulosic biobutanol using agricultural wastes and residue. Specific necessary pretreatments, fermentation strategies, bioreactor designing and kinetics, and modeling can also enhance the efficient production of biobutanol. The recent genetic engineering approaches of gene knock in, knock out, and overexpression to manipulate pathways can increase the production of biobutanol in a user friendly host organism. So far various genetic manipulation techniques like antisense RNA, TargeTron Technology and CRISPR have been used to target Clostridium acetobutylicum for biobutanol production. This review summarizes the recent research and development for the efficient production of biobutanol in various aspects.

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Authors and Affiliations

  1. Food and Biotechnology Research Centre, Pakistan Council of Scientific and Industrial Research (PCSIR), Laboratories Complex Ferozepur Road, Lahore, Pakistan

    Sana Riaz, Sania Mazhar, Syed Hussain Abidi, Naaz Abbas, Yasar Saleem, Maria Maryam, Ramsha Essa & Saira Ashfaq

  2. Pakistan Council of Scientific and Industrial Research (PCSIR) Laboratories, Islamabad, Pakistan

    Syed Hussain Abidi

  3. Pakistan Council of Scientific and Industrial Research (PCSIR) Laboratories Complex Ferozepur Road, Lahore, Pakistan

    Syed Hussain Abidi, Quratulain Syed & Abad Ali Nadeem

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  1. Sana Riaz
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  2. Sania Mazhar
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  3. Syed Hussain Abidi
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  4. Quratulain Syed
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  5. Naaz Abbas
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  8. Maria Maryam
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Contributions

NA, SM, AAN and YS designed the research theme , SR, MM, RE and SA carried out most of the data analysis, documentation, write up and discussed with all the co-author, NA, SM and SR reviewed the manuscript, QS and SHA provided all the facilities required at Instituation.

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Correspondence to Sana Riaz.

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Communicated by Erko Stackebrandt.

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Riaz, S., Mazhar, S., Abidi, S.H. et al. Biobutanol production from sustainable biomass process of anaerobic ABE fermentation for industrial applications. Arch Microbiol 204, 672 (2022). https://doi.org/10.1007/s00203-022-03284-z

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