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Saponins in Insect Pest Control

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Co-Evolution of Secondary Metabolites

Part of the book series: Reference Series in Phytochemistry ((RSP))

Abstract

Insect herbivores are dangerous to all stages of plants, e.g., vegetative as well as reproductive growth, leaves, and shoots. Some of the herbivores feed by sucking plant sap, whereas some insects choose to chew various parts of plants. Thus, all types of herbivores damage plants by feeding directly and cause multiple diseases to plants, leading to plant damage indirectly. However, due to insect attack, plants produce some bioactive compounds (which are known as saponins) to improve their defense mechanism against herbivores. These saponins are further divided into two main categories, i.e., steroidal saponins and terpenoidal saponins. Here, we have highlighted the importance of saponins from multiple plant families against various herbivores. Saponins are present in different wild plants as well as cultivated crops (e.g., soybean, tea, spinach, oat, pepper, capsicum, quinoa, and allium). Some of the saponins play a role as antifeedant while some are insecticidal to different life stages of insect pests. Thus, these saponins play an important role in plant defense against different insect pests. Moreover, different saponins are effective against stored grain pests as well as cosmopolitan insect pests. Therefore, these plant bioactive compounds could be helpful for integrated pest management in different ecosystems.

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References

  1. De Geyter E, Lambert E, Geelen D, Smagghe G (2007) Novel advances with plant saponins as natural insecticides to control pest insects. Pest Technol 1:96–105

    Google Scholar 

  2. Singh B, Kaur A (2018) Control of insect pests in crop plants and stored food grains using plant saponins: a review. LWT Food Sci Technol 87:93–101

    Article  CAS  Google Scholar 

  3. Noman A, Aqeel M, Qasim M, Haider I, Lou Y (2020) Plant-insect-microbe interaction: a love triangle between enemies in ecosystem. Sci Total Environ 699:134181

    Article  CAS  PubMed  Google Scholar 

  4. Ahmed S, Qasim M (2011) Foraging and chemical control of subterranean termites in a farm building at Faisalabad, Pakistan. Pak J Life Soc Sci 9:58–62

    Google Scholar 

  5. Husain D, Qasim M, Saleem M, Akhter M, Khan K (2014) Bioassay of insecticides against three honey bee species in laboratory conditions. Cercet Agron Mold 47:69–79

    Article  Google Scholar 

  6. Nawaz A, Ali H, Sufyan M, Gogi MD, Arif MJ et al (2019) Comparative bio-efficacy of nuclear polyhedrosis virus (NPV) and Spinosad against American bollwormm, Helicoverpa armigera (Hubner). Rev Bras Entomol. https://doi.org/10.1016/j.rbe.2019.1009.1001

  7. Hafeez M, Jan S, Nawaz M, Ali E, Ali B et al (2019) Sub-lethal effects of lufenuron exposure on spotted bollworm Earias vittella (Fab): key biological traits and detoxification enzymes activity. Environ Sci Pollut Res 26:14300–14312

    Article  CAS  Google Scholar 

  8. Qasim M, Hussian D (2015) Efficacy of insecticides against citrus psylla (Diaphorina citri Kuwayama) in field and laboratory conditions. Cercet Agron Mold 48:91–97

    Article  Google Scholar 

  9. da Silva P, Eyraud V, Carre-Pierrat M, Sivignon C, Rahioui I et al (2012) High toxicity and specificity of the saponin 3-GlcA-28-AraRhaxyl-medicagenate, from Medicago truncatula seeds, for Sitophilus oryzae. BMC Chem Biol 12:3

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  10. Qasim M, Husain D, Islam SU, Ali H, Islam W et al (2018) Effectiveness of Trichogramma chilonis Ishii against spiny bollworm in Okra and susceptibility to insecticides. J Entomol Res Stud 6:1576–1581

    Google Scholar 

  11. Hussain D, Hussain A, Qasim M, Khan J (2015) Insecticidal susceptibility and effectiveness of Trichogramma chilonis as parasitoids of tomato fruit borer, Helicoverpa armigera. Pak J Zool 47:1427–1432

    CAS  Google Scholar 

  12. Aktar W, Sengupta D, Chowdhury A (2009) Impact of pesticides use in agriculture: their benefits and hazards. Interdiscip Toxicol 2:1–12

    Article  PubMed  PubMed Central  Google Scholar 

  13. Ntalli NG, Menkissoglu-Spiroudi U (2011) Pesticides of botanical origin: a promising tool in plant protection. In: Pesticides – formulations, effects, fate. IntechOpen, Rijeka, pp 1–23

    Google Scholar 

  14. Campos EVR, Proença PLF, Oliveira JL, Bakshi M, Abhilash PC et al (2019) Use of botanical insecticides for sustainable agriculture: future perspectives. Ecol Indic 105:483–495

    Article  CAS  Google Scholar 

  15. Nawrot J, Harmatha J (2012) Phytochemical feeding deterrents for stored product insect pests. Phytochem Rev 11:543–566

    Article  CAS  Google Scholar 

  16. Kanda D, Kaur S, Koul O (2017) A comparative study of monoterpenoids and phenylpropanoids from essential oils against stored grain insects: acute toxins or feeding deterrents. J Pest Sci 90:531–545

    Article  Google Scholar 

  17. Podolak I, Galanty A, Sobolewska D (2010) Saponins as cytotoxic agents: a review. Phytochem Rev 9:425–474

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Hussain M, Debnath B, Qasim M, Bamisile BS, Islam W et al (2019) Role of saponins in plant defense against specialist herbivores. Molecules 24:2067

    Article  CAS  PubMed Central  Google Scholar 

  19. Díaz AEC, Herfindal L, Rathe BA, Sletta KY, Vedeler A et al (2019) Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. Phytochemistry 164:67–77

    Article  CAS  Google Scholar 

  20. Vincken J-P, Heng L, de Groot A, Gruppen H (2007) Saponins, classification and occurrence in the plant kingdom. Phytochemistry 68:275–297

    Article  CAS  PubMed  Google Scholar 

  21. Khan NT (2019) Therapeutic properties of saponins. Int Invent Sci J 3:409–411

    Google Scholar 

  22. Balandrin MF (1996) Commercial utilization of plant-derived saponins: an overview of medicinal, pharmaceutical, and industrial applications. In: Saponins used in traditional and modern medicine. Springer, Boston, MA pp 1–14

    Google Scholar 

  23. Addisu S, Assefa A (2016) Role of plant containing saponin on livestock production; a review. Adv Biol Res 10:309–314

    CAS  Google Scholar 

  24. Sparg SG, Light ME, Van Staden J (2004) Biological activities and distribution of plant saponins. J Ethnopharmacol 94:219–243

    Article  CAS  PubMed  Google Scholar 

  25. Kregiel D, Berlowska J, Witonska I, Antolak H, Proestos C et al (2017) Saponin-based, biological-active surfactants from plants. In: Application and characterization of surfactants. IntechOpen, Rijeka, pp 183–205

    Google Scholar 

  26. Koczurkiewicz P, Klaś K, Grabowska K, Piska K, Rogowska K et al (2019) Saponins as chemosensitizing substances that improve effectiveness and selectivity of anticancer drug – minireview of in vitro studies. Phytother Res 33:2141–2151

    Article  CAS  PubMed  Google Scholar 

  27. Hameed IH, Cotos MRC, Hadi MY (2017) A review: Solanum nigrum L. antimicrobial, antioxidant properties, hepatoprotective effects and analysis of bioactive natural compounds. Res J Pharm Technol 10:4063–4068

    Article  Google Scholar 

  28. Islam W, Qasim M, Ali N, Tayyab M, Chen S et al (2018) Management of Tobacco mosaic virus through natural metabolites. Rec Nat Prod 12:403–415

    Article  CAS  Google Scholar 

  29. Lin Y, Qasim M, Hussain M, Akutse KS, Avery PB et al (2017) The herbivore-induced plant volatiles methyl salicylate and menthol positively affect growth and pathogenicity of entomopathogenic fungi. Sci Rep 7:40494

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Stevenson PC, Dayarathna TK, Belmain SR, Veitch NC (2009) Bisdesmosidic saponins from Securidaca longepedunculata roots: evaluation of deterrency and toxicity to Coleopteran storage pests. J Agric Food Chem 57:8860–8867

    Article  CAS  PubMed  Google Scholar 

  31. Yang C, Zhang M, Lei B, Gong G, Yue G et al (2017) Active saponins from root of Pueraria peduncularis (Grah. ex Benth.) Benth. and their molluscicidal effects on Pomacea canaliculata. Pest Manag Sci 73:1143–1147

    Article  CAS  PubMed  Google Scholar 

  32. Chen H, Zhao X, Lv T, Qiu X, Luo L et al (2019) Compounds from the root of Pueraria peduncularis (Grah. ex Benth.) Benth. and their antimicrobial effects. Pest Manag Sci. https://doi.org/10.1002/ps.5387

    Article  CAS  PubMed  Google Scholar 

  33. Applebaum SW, Marco S, Birk Y (1969) Saponins as possible factors of resistance of legume seeds to the attack of insects. J Agric Food Chem 17:618–622

    Article  CAS  Google Scholar 

  34. Moses T, Papadopoulou KK, Osbourn A (2014) Metabolic and functional diversity of saponins, biosynthetic intermediates and semi-synthetic derivatives. Crit Rev Biochem Mol Biol 49:439–462

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Lei Z, Watson BS, Huhman D, Yang DS, Sumner LW (2019) Large-scale profiling of saponins in different ecotypes of Medicago truncatula. Front Plant Sci 10:850

    Article  PubMed  PubMed Central  Google Scholar 

  36. Mithöfer A, Boland W, Maffei ME (2018) Chemical ecology of plant–insect interactions. Annu Plant Rev online 34:261–291

    Article  Google Scholar 

  37. Pickett JA, Khan ZR (2016) Plant volatile-mediated signalling and its application in agriculture: successes and challenges. New Phytol 212:856–870

    Article  CAS  PubMed  Google Scholar 

  38. Nowacka J, Oleszek W (1992) High performance liquid chromatography of zanhic acid glycoside in alfalfa (Medicago sativa). Phytochem Anal 3:227–230

    Article  CAS  Google Scholar 

  39. Tava A, Biazzi E, Mella M, Quadrelli P, Avato P (2017) Artefact formation during acid hydrolysis of saponins from Medicago spp. Phytochemistry 138:116–127

    Article  CAS  PubMed  Google Scholar 

  40. Jain D, Tripathi A (1991) Insect feeding-deterrent activity of some saponin glycosides. Phytother Res 5:139–141

    Article  CAS  Google Scholar 

  41. Goławska S, Łukasik I, Goławski A, Kapusta I, Janda B (2010) Alfalfa (Medicago sativa L.) apigenin glycosides and their effect on the pea aphid (Acyrthosiphon pisum). Pol J Environ Stud 19:913–919

    Google Scholar 

  42. Thakur M, Melzig MF, Fuchs H, Weng A (2011) Chemistry and pharmacology of saponins: special focus on cytotoxic properties. Bot Targets Ther 1:19–29

    Google Scholar 

  43. Sami AJ, Bilal S, Khalid M, Nazir MT, Shakoori AR (2018) A comparative study of inhibitory properties of saponins (derived from Azadirachta indica) for acetylcholinesterase of Tribolium castaneum and Apis mellifera. Pak J Zool 50:725–733

    Article  CAS  Google Scholar 

  44. Faizal A, Geelen D (2013) Saponins and their role in biological processes in plants. Phytochem Rev 12:877–893

    Article  CAS  Google Scholar 

  45. Cai F, Watson BS, Meek D, Huhman DV, Wherritt DJ et al (2017) Medicago truncatula oleanolic-derived saponins are correlated with caterpillar deterrence. J Chem Ecol 43:712–724

    Article  CAS  PubMed  Google Scholar 

  46. Badenes-Perez FR, Gershenzon J, Heckel DG (2014) Insect attraction versus plant defense: young leaves high in glucosinolates stimulate oviposition by a specialist herbivore despite poor larval survival due to high saponin content. PLoS One 9:e95766

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  47. Cheok CY, Salman HAK, Sulaiman R (2014) Extraction and quantification of saponins: a review. Food Res Int 59:16–40

    Article  CAS  Google Scholar 

  48. Ligor M, Ratiu IA, Kiełbasa A, Al-Suod H, Buszewski B (2018) Extraction approaches used for the determination of biologically active compounds (cyclitols, polyphenols and saponins) isolated from plant material. Electrophoresis 39:1860–1874

    Article  CAS  Google Scholar 

  49. Moghimipour E, Handali S (2015) Saponin: properties, methods of evaluation and applications. Annu Res Rev Biol 5:207–220

    Article  Google Scholar 

  50. Zhou Q-L, Zhu D-N, Yang X-W, Xu W, Wang Y-P (2018) Development and validation of a UFLC–MS/MS method for simultaneous quantification of sixty-six saponins and their six aglycones: application to comparative analysis of red ginseng and white ginseng. J Pharm Biomed Anal 159:153–165

    Article  CAS  PubMed  Google Scholar 

  51. Hayashi H, Fukui H, Tabata M (1993) Distribution pattern of saponins in different organs of Glycyrrhiza glabra. Planta Med 59:351–353

    Article  CAS  PubMed  Google Scholar 

  52. Achakzai AKK, Achakzai P, Masood A, Kayani SA, Tareen RB (2009) Response of plant parts and age on the distribution of secondary metabolites on plants found in Quetta. Pak J Bot 41:2129–2135

    Google Scholar 

  53. Wei G, Dong L, Yang J, Zhang L, Xu J et al (2018) Integrated metabolomic and transcriptomic analyses revealed the distribution of saponins in Panax notoginseng. Acta Pharm Sin B 8:458–465

    Article  PubMed  PubMed Central  Google Scholar 

  54. Phrompittayarat W, Jetiyanon K, Wittaya-Areekul S, Putalun W, Tanaka H et al (2011) Influence of seasons, different plant parts, and plant growth stages on saponin quantity and distribution in Bacopa monnieri. Songklanakarin J Sci Technol 33:193–199

    CAS  Google Scholar 

  55. Singh B, Singh JP, Singh N, Kaur A (2017) Saponins in pulses and their health promoting activities: a review. Food Chem 233:540–549

    Article  CAS  PubMed  Google Scholar 

  56. Mroczek A, Kapusta I, Stochmal A, Janiszowska W (2019) MS/MS and UPLC-MS profiling of triterpenoid saponins from leaves and roots of four red beet (Beta vulgaris L.) cultivars. Phytochem Lett 30:333–337

    Article  CAS  Google Scholar 

  57. Colson E, Decroo C, Cooper-Shepherd D, Caulier G, Henoumont C et al (2019) Discrimination of regioisomeric and stereoisomeric saponins from Aesculus hippocastanum seeds by ion mobility mass spectrometry. J Am Soc Mass Spectrom 30(11):2228–2237

    Article  CAS  PubMed  Google Scholar 

  58. Nomura Y, Seki H, Suzuki T, Ohyama K, Mizutani M et al (2019) Functional specialization of UDP-glycosyltransferase 73P12 in licorice to produce a sweet triterpenoid saponin, glycyrrhizin. Plant J. https://doi.org/10.1111/tpj.14409

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  59. Yang H, Piao X, Zhang L, Song S, Xu Y (2018) Ginsenosides from the stems and leaves of Panax ginseng show antifeedant activity against Plutella xylostella (Linnaeus). Ind Crop Prod 124:412–417

    Article  CAS  Google Scholar 

  60. Heinz P, Glomb MA (2018) Characterization and quantitation of steryl glycosides in Solanum melongena. J Agric Food Chem 66:11398–11406

    Article  CAS  PubMed  Google Scholar 

  61. Siddiqui MA, Ali Z, Chittiboyina AG, Khan IA (2018) Hepatoprotective effect of steroidal glycosides from Dioscorea villosa on hydrogen peroxide-induced hepatotoxicity in HepG2 cells. Front Pharmacol 9:797

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  62. Sun Z, Huang X, Kong L (2010) A new steroidal saponin from the dried stems of Asparagus officinalis L. Fitoterapia 81:210–213

    Article  CAS  PubMed  Google Scholar 

  63. Yahara S, Ura T, Sakamoto C, Nohara T (1994) Steroidal glycosides from Capsicum annuum. Phytochemistry 37:831–835

    Article  CAS  PubMed  Google Scholar 

  64. Güçlü-Üstündağ Ö, Mazza G (2007) Saponins: properties, applications and processing. Crit Rev Food Sci Nutr 47:231–258

    Article  PubMed  CAS  Google Scholar 

  65. Hassan SM, Byrd JA, Cartwright AL, Bailey CA (2010) Hemolytic and antimicrobial activities differ among saponin-rich extracts from guar, quillaja, yucca, and soybean. Appl Biochem Biotechnol 162:1008–1017

    Article  CAS  PubMed  Google Scholar 

  66. Zehring J, Reim V, Schröter D, Neugart S, Schreiner M et al (2015) Identification of novel saponins in vegetable amaranth and characterization of their hemolytic activity. Food Res Int 78:361–368

    Article  CAS  PubMed  Google Scholar 

  67. Ling Y, Lin Z, Zha W, Lian T, You S (2016) Rapid detection and characterisation of triterpene saponins from the root of Pulsatilla chinensis (Bunge) Regel by HPLC-ESI-QTOF-MS/MS. Phytochem Anal 27:174–183

    Article  CAS  PubMed  Google Scholar 

  68. Böttcher S, Drusch S (2016) Interfacial properties of saponin extracts and their impact on foam characteristics. Food Biophys 11:91–100

    Article  Google Scholar 

  69. Guajardo-Flores D, García-Patiño M, Serna-Guerrero D, Gutiérrez-Uribe JA, Serna-Saldívar SO (2012) Characterization and quantification of saponins and flavonoids in sprouts, seed coats and cotyledons of germinated black beans. Food Chem 134:1312–1319

    Article  CAS  PubMed  Google Scholar 

  70. Ha TJ, Lee BW, Park KH, Jeong SH, Kim H-T et al (2014) Rapid characterisation and comparison of saponin profiles in the seeds of Korean Leguminous species using ultra performance liquid chromatography with photodiode array detector and electrospray ionisation/mass spectrometry (UPLC–PDA–ESI/MS) analysis. Food Chem 146:270–277

    Article  CAS  PubMed  Google Scholar 

  71. Lee YH, Kim B, Hwang S-R, Kim K, Lee JH (2018) Rapid characterization of metabolites in soybean using ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC-ESI-Q-TOF-MS/MS) and screening for α-glucosidase inhibitory and antioxidant properties through different solvent systems. J Food Drug Anal 26:277–291

    Article  CAS  PubMed  Google Scholar 

  72. Bitencourt RG, Queiroga CL, Duarte GHB, Eberlin MN, Kohn LK et al (2014) Sequential extraction of bioactive compounds from Melia azedarach L. in fixed bed extractor using CO2, ethanol and water. J Supercrit Fluids 95:355–363

    Article  CAS  Google Scholar 

  73. Nguyen VT, Vuong QV, Bowyer MC, Van Altena IA, Scarlett CJ (2017) Microwave-assisted extraction for saponins and antioxidant capacity from Xao tam phan (Paramignya trimera) root. J Food Process Preserv 41:e12851

    Article  CAS  Google Scholar 

  74. Mohaddes-Kamranshahi M, Jafarizadeh-Malmiri H, Simjoo M, Jafarizad A (2019) Evaluation of the saponin green extraction from Ziziphus spina-christi leaves using hydrothermal, microwave and Bain-Marie water bath heating methods. Green Process Synth 8:62–67

    Article  CAS  Google Scholar 

  75. Elhag HEEA, Naila A, Ajit A, Aziz BA, Sulaiman AZ (2018) Sequential extraction of saponins from Eurycoma longifolia roots by water extraction and ultrasound-assisted extraction. Mater Today Proc 5:21672–21681

    Article  CAS  Google Scholar 

  76. Khan H, Khan MA, Abdullah (2012) Antibacterial, antioxidant and cytotoxic studies of total saponin, alkaloid and sterols contents of decoction of Joshanda: identification of components through thin layer chromatography. Toxicol Ind Health 31:202–208

    Article  PubMed  CAS  Google Scholar 

  77. Dinda B, Debnath S, Mohanta BC, Harigaya Y (2010) Naturally occurring triterpenoid saponins. Chem Biodivers 7:2327–2580

    Article  CAS  PubMed  Google Scholar 

  78. Niiho Y, Nakajima Y, Yamazaki T, Okamoto M, Tsuchihashi R et al (2010) Simultaneous analysis of isoflavones and saponins in Pueraria flowers using HPLC coupled to an evaporative light scattering detector and isolation of a new isoflavone diglucoside. J Nat Med 64:313–320

    Article  CAS  PubMed  Google Scholar 

  79. Ma Y, Shang Y, Zhong Z, Zhang Y, Yang Y et al (2019) A new isoflavone glycoside from flowers of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep. Nat Prod Res 1–6 In press, https://doi.org/10.1080/14786419.2019.1655021

  80. Oleszek WA (2002) Chromatographic determination of plant saponins. J Chromatogr A 967:147–162

    Article  CAS  PubMed  Google Scholar 

  81. Reim V, Rohn S (2015) Characterization of saponins in peas (Pisum sativum L.) by HPTLC coupled to mass spectrometry and a hemolysis assay. Food Res Int 76:3–10

    Article  CAS  Google Scholar 

  82. Hassan SA, Jassim EH (2018) Effect of l-phenylalanine on the production of some alkaloids and steroidal saponins of fenugreek cotyledons derived callus. Pak J Biotechnol 15:481–486

    Google Scholar 

  83. Sharma V, Paliwal R (2014) Potential chemoprevention of 7,12-dimethylbenz[a]anthracene induced renal carcinogenesis by Moringa oleifera pods and its isolated saponin. Indian J Clin Biochem 29:202–209

    Article  CAS  PubMed  Google Scholar 

  84. Malongane F, McGaw LJ, Nyoni H, Mudau FN (2018) Metabolic profiling of four South African herbal teas using high resolution liquid chromatography-mass spectrometry and nuclear magnetic resonance. Food Chem 257:90–100

    Article  CAS  PubMed  Google Scholar 

  85. Ge Y, Chen X, Gođevac D, Bueno PCP, Abarca LFS et al (2019) Metabolic profiling of saponin-rich Ophiopogon japonicus roots based on 1H NMR and HPTLC platforms. Planta Med 85:917–924

    Article  CAS  PubMed  Google Scholar 

  86. Chaieb I (2010) Saponins as insecticides: a review. Tunis J Plant Prot 5:39–50

    Google Scholar 

  87. Adel MM, Sehnal F, Jurzysta M (2000) Effects of alfalfa saponins on the moth Spodoptera littoralis. J Chem Ecol 26:1065–1078

    Article  CAS  Google Scholar 

  88. Cai H, Bai Y, Wei H, Lin S, Chen Y et al (2016) Effects of tea saponin on growth and development, nutritional indicators, and hormone titers in diamondback moths feeding on different host plant species. Pestic Biochem Physiol 131:53–59

    Article  CAS  PubMed  Google Scholar 

  89. Taylor WG, Fields PG, Sutherland DH (2004) Insecticidal components from field pea extracts: soyasaponins and lysolecithins. J Agric Food Chem 52:7484–7490

    Article  CAS  PubMed  Google Scholar 

  90. De Geyter E, Smagghe G, Rahbé Y, Geelen D (2012) Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum. Pest Manag Sci 68:164–169

    Article  PubMed  CAS  Google Scholar 

  91. De Geyter E (2012) Toxicity and mode of action of steroid and terpenoid secondary plant metabolites against economically important pest insects in agriculture. Ghent University, p 137

    Google Scholar 

  92. Pedersen MW, Barnes DK, Sorensen EL, Griffin GD, Nielson MW et al (1976) Effects of low and high saponin selection in alfalfa on agronomic and pest resistance traits and the interrelationship of these traits. Crop Sci Washington, D.C. USA 16:193–199

    Google Scholar 

  93. Sylwia G, Leszczynski B, Wieslaw O (2006) Effect of low and high-saponin lines of alfalfa on pea aphid. J Insect Physiol 52:737–743

    Article  PubMed  CAS  Google Scholar 

  94. Goławska S, Łukasik I, Kapusta I, Janda B (2012) Do the contents of luteolin, tricin, and chrysoeriol glycosides in alfalfa (Medicago sativa L.) affect the behavior of pea aphid (Acyrthosiphon pisum)? Pol J Environ Stud 21:1613–1619

    Google Scholar 

  95. Nozzolillo C, Arnason JT, Campos F, Donskov N, Jurzysta M (1997) Alfalfa leaf saponins and insect resistance. J Chem Ecol 23:995–1002

    Article  CAS  Google Scholar 

  96. Agerbirk N, Olsen CE, Bibby BM, Frandsen HO, Brown LD et al (2003) A saponin correlated with variable resistance of Barbarea vulgaris to the diamondback moth Plutella xylostella. J Chem Ecol 29:1417–1433

    Article  CAS  PubMed  Google Scholar 

  97. Shinoda T, Nagao T, Nakayama M, Serizawa H, Koshioka M et al (2002) Identification of a triterpenoid saponin from a crucifer, Barbarea vulgaris, as a feeding deterrent to the diamondback moth, Plutella xylostella. J Chem Ecol 28:587–599

    Article  CAS  PubMed  Google Scholar 

  98. Gao G, Lu Z, Tao S, Zhang S, Wang F (2011) Triterpenoid saponins with antifeedant activities from stem bark of Catunaregam spinosa (Rubiaceae) against Plutella xylostella (Plutellidae). Carbohydr Res 346:2200–2205

    Article  CAS  PubMed  Google Scholar 

  99. Rattan R, Reddy SGE, Dolma SK, Fozdar BI, Gautam V et al (2015) Triterpenoid saponins from Clematis graveolens and evaluation of their insecticidal activities. Nat Prod Commun 10:1525–1528

    PubMed  Google Scholar 

  100. Mudalungu CM (2013) Mosquito larvicidal compounds from the plant Fagaropsis angolensis (Engl. Dale) against Anopheles gambiae. MS thesis, Egerton University

    Google Scholar 

  101. Liu X-Y, Li C-J, Chen F-Y, Ma J, Wang S et al (2018) Nototronesides A–C, three triterpene saponins with a 6/6/9 fused tricyclic tetranordammarane carbon skeleton from the leaves of Panax notoginseng. Org Lett 20:4549–4553

    Article  CAS  PubMed  Google Scholar 

  102. Zhang A, Liu Z, Lei F, Fu J, Zhang X et al (2017) Antifeedant and oviposition-deterring activity of total ginsenosides against Pieris rapae. Saudi J Biol Sci 24:1751–1753

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  103. De Geyter E, Geelen D, Smagghe G (2007) First results on the insecticidal action of saponins. Commun Agric Appl Biol Sci 72:645

    PubMed  Google Scholar 

  104. Soulé S, Güntner C, Vazquez A, Argandona V, Moyna P et al (2000) An aphid repellent glycoside from Solanum laxum. Phytochemistry 55:217–222

    Article  PubMed  Google Scholar 

  105. Ray DP, Dutta D, Srivastava S, Kumar B, Saha S (2013) Insect growth regulatory activity of Thevetia nerifolia Juss. against Spodoptera litura (Fab.). J Appl Bot Food Qual 85:212–215

    Google Scholar 

  106. Pemonge J, Pascual-Villalobos MJ, Regnault-Roger C (1997) Effects of material and extracts of Trigonella foenum-graecum L. against the stored product pests Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) and Acanthoscelides obtectus (Say) (Coleoptera: Bruchidae). J Stored Prod Res 33:209–217

    Article  Google Scholar 

  107. Lanzotti V (2005) Bioactive saponins from Allium and Aster plants. Phytochem Rev 4:95–110

    Article  CAS  Google Scholar 

  108. Kim HK, Khan S, Wilson EG, Kricun SDP, Meissner A et al (2010) Metabolic classification of South American Ilex species by NMR-based metabolomics. Phytochemistry 71:773–784

    Article  CAS  PubMed  Google Scholar 

  109. Kothiyal SK, Sati SC, Rawat MSM, Sati MD, Semwal DK et al (2012) Chemical constituents and biological significance of the genus Ilex (Aquifoliaceae). Nat Prod J 2:212–224

    CAS  Google Scholar 

  110. Kreuger B, Potter DA (1994) Changes in saponins and tannins in ripening holly fruits and effects of fruit consumption on nonadapted insect herbivores. Am Midl Nat 132:183–191

    Article  Google Scholar 

  111. Brito FCd, Gosmann G, Oliveira GT (2019) Extracts of the unripe fruit of Ilex paraguariensis as a potential chemical control against the golden apple snail Pomacea canaliculata (Gastropoda, Ampullariidae). Nat Prod Res 33:2379–2382

    Article  CAS  Google Scholar 

  112. Colpo AC, Lima ME, da Rosa HS, Leal AP, Colares CC et al (2018) Ilex paraguariensis extracts extend the lifespan of Drosophila melanogaster fed a high-fat diet. Braz J Med Biol Res 51:e6784

    Article  CAS  Google Scholar 

  113. Frodin DG, Dassanayake MD (2017) Araliaceae. In: A revised handbook to the flora of Ceylon, University of Peradeniya, Sri Lanka vol 10. Routledge

    Google Scholar 

  114. Kemertelidze ÉP, Kemoklidze ZS, Dekanosidze GE, Bereznyakova AI (2001) Isolation and pharmacological characterization of triterpenoid glycosides from Fatsia japonica cultivated in Georgia. Pharm Chem J 35:429–432

    Article  CAS  Google Scholar 

  115. Cheng H-L, Cheng S-Y, Huang S-D, Lu Y-T, Wang X-W et al (2013) Anti-inflammatory effects and mechanisms of Fatsia polycarpa Hayata and its constituents. Evid Based Complement Alternat Med 2013:857213

    PubMed  PubMed Central  Google Scholar 

  116. Liu J, Xu Q, Zhao X (2010) Extraction of total saponins in Aralia elata Seem by herbal flash extractor. Mod Food Sci Technol 26:622–624

    CAS  Google Scholar 

  117. Lan-xiang PU (2010) Analysis on volatile constituents of Aralia cordata Thunb. from different places. J Anhui Agric Sci 38(17): 8946–8948

    Google Scholar 

  118. Ye X, Yu S, Lian X-Y, Zhang Z (2014) Quantitative determination of triterpenoid glycosides in Fatsia japonica Decne. & Planch. using high performance liquid chromatography. J Pharm Biomed Anal 88:472–476

    Article  CAS  PubMed  Google Scholar 

  119. Park S-J, Lee S-G, Shin S-C, Lee B-Y, Ahn Y-J (1997) Larvicidal and antifeeding activities of oriental medicinal plant extracts against four species of forest insect pests. Appl Entomol Zool 32:601–608

    Article  Google Scholar 

  120. Zhang A-H, Tan S-Q, Zhao Y, Lei F-J, Zhang L-X (2015) Effects of total ginsenosides on the feeding behavior and two enzymes activities of Mythimna separata (Walker) larvae. Evid Based Complement Alternat Med 2015:451828

    PubMed  PubMed Central  Google Scholar 

  121. Liu S, Wang X, Xu Y, Zhang R, Xiao S et al (2019) Antifeedant and ovicidal activities of ginsenosides against Asian corn borer, Ostrinia furnacalis (Guenee). PLoS One 14:e0211905

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  122. Feng Y, Wu M-L, Li T-L, Fan W-L (2010) Purification of saponin from edible stems of Aralia continentalis using macroporous adsorption resin. Food Sci 31:73–76

    CAS  Google Scholar 

  123. Pérez AJ, Simonet AM, Calle JM, Pecio Ł, Guerra JO et al (2014) Phytotoxic steroidal saponins from Agave offoyana leaves. Phytochemistry 105:92–100

    Article  PubMed  CAS  Google Scholar 

  124. Sharma U, Kumar N, Singh B (2012) Furostanol saponin and diphenylpentendiol from the roots of Asparagus racemosus. Nat Prod Commun 7:995–998

    CAS  PubMed  Google Scholar 

  125. Onlom C, Nuengchamnong N, Phrompittayarat W, Putalun W, Waranuch N et al (2017) Quantification of saponins in Asparagus racemosus by HPLC-Q-TOF-MS/MS. Nat Prod Commun 12:7–10

    PubMed  Google Scholar 

  126. de Oliveira LHG, de Sousa PAPS, Hilario FF, Nascimento GJ, Morais JPS et al (2016) Agave sisalana extract induces cell death in Aedes aegypti hemocytes increasing nitric oxide production. Asian Pac J Trop Biomed 6:396–399

    Article  Google Scholar 

  127. Zhou L, Cheng Z, Chen D (2012) Simultaneous determination of six steroidal saponins and one ecdysone in Asparagus filicinus using high performance liquid chromatography coupled with evaporative light scattering detection. Acta Pharm Sin B 2:267–273

    Article  CAS  Google Scholar 

  128. Herbert-Doctor LA, Saavedra-Aguilar M, Villarreal ML, Cardoso-Taketa A, Vite-Vallejo O (2016) Insecticidal and nematicidal effects of Agave tequilana juice against Bemisia tabaci and Panagrellus redivivus. Southwest Entomol 41:27–41

    Article  Google Scholar 

  129. Barkley T, Brouillet L, Strother J (2006) Flora of North America, Asteraceae, part 1. Oxford University Press, New York

    Google Scholar 

  130. Afzal H, Ahmed S, Khan RR, Sufyan M, Arshid M et al (2019) Management of house fly, Musca domestica L. (Muscidae: Diptera), through botanical baits. Rev Bras Entomol. Accepted In press

    Google Scholar 

  131. Obeng-Ofori D, Akuamoah RK (2000) Biological effects of plant extracts against the rice weevil Sitophilus oryzae in stored maize. J Ghana Sci Assoc 2:62–69

    Google Scholar 

  132. Udebuani AC, Abara PC, Obasi KO, Okuh SU (2015) Studies on the insecticidal properties of Chromolaena odorata (Asteraceae) against adult stage of Periplaneta americana. J Entomol Zool Stud 3:318–321

    Google Scholar 

  133. Al-Shehbaz I, Beilstein MA, Kellogg E (2006) Systematics and phylogeny of the Brassicaceae (Cruciferae): an overview. Plant Syst Evol 259:89–120

    Article  Google Scholar 

  134. Kuzina V, Ekstrøm CT, Andersen SB, Nielsen JK, Olsen CE et al (2009) Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach. Plant Physiol 151:1977–1990

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  135. Nielsen JK, Nagao T, Okabe H, Shinoda T (2010) Resistance in the plant, Barbarea vulgaris, and counter-adaptations in flea beetles mediated by saponins. J Chem Ecol 36:277–285

    Article  CAS  PubMed  Google Scholar 

  136. Talekar NS, Shelton AM (1993) Biology, ecology, and management of the diamondback moth. Annu Rev Entomol 38:275–301

    Article  Google Scholar 

  137. Idris AB, Grafius E (1996) Effects of wild and cultivated host plants on oviposition, survival, and development of diamondback moth (Lepidoptera: Plutellidae) and its parasitoid Diadegma insulare (Hymenoptera: Ichneumonidae). Environ Entomol 25:825–833

    Article  Google Scholar 

  138. Badenes-Perez FR, Reichelt M, Heckel DG (2010) Can sulfur fertilisation improve the effectiveness of trap crops for diamondback moth, Plutella xylostella (L.) (Lepidoptera: Plutellidae)? Pest Manag Sci 66:832–838

    CAS  PubMed  Google Scholar 

  139. Badenes-Perez FR, Reichelt M, Gershenzon J, Heckel DG (2014) Using plant chemistry and insect preference to study the potential of Barbarea (Brassicaceae) as a dead-end trap crop for diamondback moth (Lepidoptera: Plutellidae). Phytochemistry 98:137–144

    Article  CAS  PubMed  Google Scholar 

  140. Wojciechowski MF, Mahn J, Jones B (2006) Fabaceae legumes. Version 14 June 2006

    Google Scholar 

  141. Wiersema JH, Kirkbride JH, Gunn CR (1990) Legume (Fabaceae) nomenclature in the USDA germplasm system. US Department of Agriculture, Agricultural Research Service, Beltsville, pp 1–10

    Google Scholar 

  142. Goławska S (2007) Deterrence and toxicity of plant saponins for the pea aphid Acyrthosiphon pisum Harris. J Chem Ecol 33:1598–1606

    Article  PubMed  CAS  Google Scholar 

  143. Goławska S, Łukasik I (2009) Acceptance of low-saponin lines of alfalfa with varied phenolic concentrations by pea aphid (Homoptera: Aphididae). Biologia 64:377–382

    Article  CAS  Google Scholar 

  144. Goławska S, Sprawka I, Łukasik I (2014) Effect of saponins and apigenin mixtures on feeding behavior of the pea aphid, Acyrthosiphon pisum Harris. Biochem Syst Ecol 55:137–144

    Article  CAS  Google Scholar 

  145. Mazahery-Laghab H (1997) Endogenous resistance to insect pests in alfalfa: engineering for enhanced resistance. Durham University, Durham

    Google Scholar 

  146. Horber E, Leath KT, Berrang B, Marcarian V, Hanson CH (1974) Biological activities of saponin components from Dupuits and Lahontan alfalfa. Entomol Exp Appl 17:410–424

    Article  CAS  Google Scholar 

  147. Applebaum SW, Gestetner BE, Birk Y (1965) Physiological aspects of host specificity in the Bruchidae – IV. Developmental incompatibility of soybeans for Callosobruchus. J Insect Physiol 11:611–616

    Article  Google Scholar 

  148. Shany S, Gestetner B, Birk Y, Bondi A (1970) Lucerne saponins III. Effect of lucerne saponins on larval growth and their detoxification by various sterols. J Sci Food Agric 21:508–510

    Article  CAS  PubMed  Google Scholar 

  149. Szczepaniak M, Krystkowiak K, Jurzysta M, Biały Z (2001) Biological activity of saponins from alfalfa tops and roots against Colorado potato beetle larvae. Acta Agrobot 54:35–45

    Article  Google Scholar 

  150. Szczepanik M, Bialy Z, Jurzysta M (2004) The insecticidal activity of saponins from various Medicago spp. against Colorado potato beetle, Leptinotarsa decemlineata Say. Allelopath J 14:177–185

    Google Scholar 

  151. Hussein HM, Dimetry N, Zidan Z, Iss-hak RR, Sehnal F (2005) Effects of insect growth regulators on the hairy rose beetle, Tropinota squalida (Col., Scarabeidae). J Appl Entomol Springer, Berlin, Heidelberg 129:142–148

    Article  CAS  Google Scholar 

  152. Feuillet C, MacDougal J (2007) Passifloraceae. In: Flowering plants· eudicots. Springer, pp 270–281

    Google Scholar 

  153. Holm-Nielsen LB, Jørgensen PM, Lawesson JE (1988) Passifloraceae. Flora of Ecuador, no 3. Pontificia Universidad Católica del Ecuador, Stockholm, p 124

    Google Scholar 

  154. D’Incao MP, Gosmann G, Machado V, Fiuza LM, Moreira GR (2012) Effect of saponin extracted from Passiflora alata Dryander (Passifloraceae) on development of the Spodoptera frugiperda (JE Smith) (Lepidoptera, Noctuidae). Int J Plant Res 2:151–159

    Article  Google Scholar 

  155. Mason PG, Weiss RM, Olfert O, Appleby M, Landry JF (2011) Actual and potential distribution of Acrolepiopsis assectella (Lepidoptera: Acrolepiidae), an invasive alien pest of Allium spp. in Canada. Can Entomol 143:185–196

    Article  Google Scholar 

  156. Luebert F (2014) Taxonomy and distribution of the genus Quillaja Molina (Quillajaceae). Feddes Repert 124:157–162

    Article  Google Scholar 

  157. Waligóra D (2006) Activity of the saponin extract from the bark of Quillaja saponaria Molina, against Colorado potato beetle (Leptinotarsa decemlineata Say). J Plant Prot Res 46:199–206

    Google Scholar 

  158. Wegorek P (2005) Current status of resistance in Colorado potato beetle (Leptinotarsa decemlineata Say) to selected active substances of insecticides in Poland. J Plant Prot Res 45:309–319

    CAS  Google Scholar 

  159. Waligora D (1999) Biological activity of secondary plant substances glucosinolates, alkaloids and saponins, expressed by their effects on development of Colorado potato beetle, Leptinotarsa decemlineata Say. J Plant Prot Res 38:158–173

    Google Scholar 

  160. Robbrecht E (1988) Tropical woody Rubiaceae: characteristic features and progressions. National Botanic Garden of Belgium, Meise

    Google Scholar 

  161. Mocan A, Crisan G, Vlase L, Ivanescu B, Badarau AS et al (2016) Phytochemical investigations on four Galium species (Rubiaceae) from Romania. Farmacia 64:95–99

    CAS  Google Scholar 

  162. Pavela R (2010) Antifeedant activity of plant extracts on Leptinotarsa decemlineata Say. and Spodoptera littoralis Bois. larvae. Ind Crop Prod 32:213–219

    Article  Google Scholar 

  163. Acevedo-Rodríguez P, Van Welzen P, Adema F, Van der Ham R (2010) Sapindaceae. In: Flowering plants eudicots. Springer, Berlin, Heidelberg pp 357–407

    Chapter  Google Scholar 

  164. Bürki S (2009) Worldwide biogeography and systematics of Sapindaceae. Université de Neuchâtel UniMail building, 2000 Neuchâtel - Switzerland

    Google Scholar 

  165. Saha S, Walia S, Kumar J, Dhingra S, Parmar BS (2010) Screening for feeding deterrent and insect growth regulatory activity of triterpenic saponins from Diploknema butyracea and Sapindus mukorossi. J Agric Food Chem 58:434–440

    Article  CAS  PubMed  Google Scholar 

  166. Lavaud C, Crublet M-L, Pouny I, Litaudon M, Sévenet T (2001) Triterpenoid saponins from the stem bark of Elattostachys apetala. Phytochemistry 57:469–478

    Article  CAS  PubMed  Google Scholar 

  167. Pertuit D, Mitaine-Offer A-C, Miyamoto T, Tanaka C, Tran DK et al (2019) Triterpenoid saponins from the root bark of Haplocoelum congolanum. Nat Prod Commun 14. https://doi.org/10.1177/1934578X19851369

    Article  Google Scholar 

  168. Eddaya T, Boughdad A, Sibille E, Chaimbault P, Zaid A et al (2013) Biological activity of Sapindus mukorossi Gaerten (Sapindaceae) aqueous extract against Thysanoplusia orichalcea (Lepidoptera: Noctuidae). Ind Crop Prod 50:325–332

    Article  Google Scholar 

  169. Sharma A, Sati SC, Sati OP, Sati MD, Kothiyal SK (2012) Triterpenoid saponins from the pericarps of Sapindus mukorossi. J Chem 2013:613190

    Google Scholar 

  170. Li R, Wu ZL, Wang YJ, Li LL (2013) Separation of total saponins from the pericarp of Sapindus mukorossi Gaerten. by foam fractionation. Ind Crop Prod 51:163–170

    Article  CAS  Google Scholar 

  171. Olmstead RG, Bohs L (2007) A summary of molecular systematic research in Solanaceae: 1982–2006. Acta Hort. 745, ISHS 2007, VIth International Solanaceae Conference, 255–268

    Google Scholar 

  172. D’Arcy WG (1986) Solanaceae, biology and systematics. Columbia University Press, New York

    Google Scholar 

  173. Olmstead RG, Bohs L, Migid HA, Santiago-Valentin E, Garcia VF et al (2008) A molecular phylogeny of the Solanaceae. Taxon 57:1159–1181

    Article  Google Scholar 

  174. Raman K, Tingey WM, Gregory P (1979) Potato glycoalkaloids: effect on survival and feeding behavior of the potato leafhopper. J Econ Entomol 72:337–341

    Article  CAS  Google Scholar 

  175. Sanford LL, Deahl KL, Sinden SL, Ladd TL (1990) Foliar solanidine glycoside levels in Solanum tuberosum populations selected for potato leafhopper resistance. Am Potato J 67:461–466

    Article  CAS  Google Scholar 

  176. Flanders KL, Hawkes JG, Radcliffe EB, Lauer FI (1992) Insect resistance in potatoes: sources, evolutionary relationships, morphological and chemical defenses, and ecogeographical associations. Euphytica 61:83–111

    Article  CAS  Google Scholar 

  177. Sanford LL, Domek JM, Cantelo WW, Kobayashi RS, Sinden SL (1996) Mortality of potato leafhopper adults on synthetic diets containing seven glycoalkaloids synthesized in the foliage of various Solanum species. Am Potato J 73:79–88

    Article  CAS  Google Scholar 

  178. Iorizzi M, Lanzotti V, Ranalli G, De Marino S, Zollo F (2002) Antimicrobial furostanol saponins from the seeds of Capsicum annuum L. var. acuminatum. J Agric Food Chem 50:4310–4316

    Article  CAS  PubMed  Google Scholar 

  179. Shukla YN, Rani A, Tripathi AK, Sharma S (1996) Antifeedant activity of ursolic acid isolated from Duboisia myoporoides. Phytother Res 10:359–360

    Article  CAS  Google Scholar 

  180. Ikbal C, Monia BH-K, Mounir T, Wassila H, Najet R et al (2007) Pesticidal potentialities of Cestrum parqui saponins. Int J Agric Res 2:275–281

    Article  Google Scholar 

  181. Stevens PF, Dressler S, Weitzman AL (2004) Theaceae. In: The families of and genera of flowering plants, vol 6. Flowering plants· Dicotyledons. Springer, Berlin, Heidelberg pp 463–471

    Chapter  Google Scholar 

  182. Liang D, Baas P (1991) The wood anatomy of the Theaceae. IAWA J 12:333–353

    Article  Google Scholar 

  183. Luna I, Ochoterena H (2004) Phylogenetic relationships of the genera of Theaceae based on morphology. Cladistics 20:223–270

    Article  PubMed  Google Scholar 

  184. Hui W, Shixi Z, Jinfeng H (2006) Influence of host plants on the resistance recession and esterase activity of Plutella xylostella L. field population. J Fujian Agric For Univ 35:138–142

    Google Scholar 

  185. Dolma SK, Sharma E, Gulati A, Reddy SGE (2018) Insecticidal activities of tea saponin against diamondback moth, Plutella xylostella and aphid, Aphis craccivora. Toxin Rev 37:52–55

    Article  CAS  Google Scholar 

  186. Lin S, Chen Y, Bai Y, Cai H, Wei H et al (2018) Effect of tea saponin-treated host plants on activities of antioxidant enzymes in larvae of the diamondback moth Plutella xylostella (Lepidoptera: Plutellidae). Environ Entomol 47:749–754

    Article  CAS  PubMed  Google Scholar 

  187. Wang X-Y, Huang B-Q (1999) Studies on modes and mechanisms of antifeeding action of tea saponin against imported cabbage worm Pieris rapae L. Entomol Knowl 23:22–24

    Google Scholar 

  188. Su Y, Ye Y (2012) Tea saponin biological pesticide and preparation method as well as application thereof. Patent no CN102511510-A

    Google Scholar 

  189. Adebisi O, Dolma SK, Verma PK, Singh B, Reddy SE (2019) Volatile, non-volatile composition and insecticidal activity of Eupatorium adenophorum Spreng against diamondback moth, Plutella xylostella (L.), and aphid, Aphis craccivora Koch. Toxin Rev 38:143–150

    Article  CAS  Google Scholar 

  190. Roof M, Horber E, Sorensen EL (1974) Effect of saponin on the potato leafhopper, Empoasca fabae (Homoptera: Cicadellidae). J Kansas Entomol Soc 47:538–539

    Google Scholar 

  191. Zeng C, Wu L, Zhao Y, Yun Y, Peng Y (2018) Tea saponin reduces the damage of Ectropis obliqua to tea crops, and exerts reduced effects on the spiders Ebrechtella tricuspidata and Evarcha albaria compared to chemical insecticides. PeerJ 6:e4534

    Article  PubMed  PubMed Central  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, People’s Republic of China

    Muhammad Qasim

  2. College of Geography, Fujian Normal University, Fuzhou, People’s Republic of China

    Waqar Islam

  3. College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, China

    Hafiza Javaria Ashraf & Liande Wang

  4. Entomological Research Institute, Ayub Agricultural Research Institute, Faisalabad, Pakistan

    Imran Ali

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  1. Muhammad Qasim
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  2. Waqar Islam
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  3. Hafiza Javaria Ashraf
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  4. Imran Ali
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  5. Liande Wang
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Correspondence to Muhammad Qasim or Liande Wang .

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  1. Faculty of Pharmaceutical Sciences, Institute of Vine and Wine Sciences, University of Bordeaux, Villenave d'Ornon, France

    Jean-Michel Mérillon

  2. Department of Botany, University College of Science, M. L. Sukhadia University, Udaipur, Rajasthan, India

    Kishan Gopal Ramawat

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Qasim, M., Islam, W., Ashraf, H.J., Ali, I., Wang, L. (2020). Saponins in Insect Pest Control. In: Mérillon, JM., Ramawat, K. (eds) Co-Evolution of Secondary Metabolites. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-96397-6_39

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