Abstract
While not agreeing on the mechanisms involved, many of the leading researchers in the field of Bioelectrochemistry/Biomagnetics agree that exogenous fields modify cellular calcium ion transport. Chiabrera et al. (1) in discussing their membrane receptor model of electric field/cell interactions state that they “adhere to the working hypothesis that when two or more receptors encounter each other, they form an encounter complex which appears to enhance calcium ion influx”, if an endogenous or exogenous electric field is present. Liboff (2), on the other hand, indicates exogenous fields cause a resonant energy transfer to potassium ion influx, which is turn causes increased calcium ion efflux via a potassium/calcium ion transmembrane exchange. Adey and his associates (3,4) have experimentally verified that calciurn-45 efflux from the external bilipid layers of chick cerebral hemisphere can be either enhanced or diminished, depending upon stimulation frequency, energy level and the type of stimulation, i.e., modulated RF or sinusoidal AC. Neumann (5) states that regions adjacent to membrane surfaces are the targets of electric field effects, altering ionic diffusion. In particular, calcium ion influx is caused by an increased concentration gradient on the external bilayer due to field-membrane interactions.
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Findl, E. (1987). Membrane Transduction of Low Energy Level Fields and the Ca++ Hypothesis. In: Blank, M., Findl, E. (eds) Mechanistic Approaches to Interactions of Electric and Electromagnetic Fields with Living Systems. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1968-7_2
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