Collection

Upconversion fluorescent nanomaterials for biodetection and bioimaging

Traditional fluorophores including fluorescent dyes/proteins and quantum dots are based on ‘downconversion fluorescence’, converting high energy photons to low energy photons. Upconversion nanoparticles (UCNPs) present a new technology for sensitive imaging and detection in various fields. Unlike traditional fluorophores, UCNPs emit detectable high energy fluorescence in the UV/visible/NIR range upon irradiation with NIR light based on a process termed ‘upconversion’. They can be used for ultrasensitive interference-free biodetection/imaging because most biomolecules do not have this upconversion property. The major advantages of this approach include but are not limited to: multi-color, low background autofluorescence, single wavelength excitation, good photostability, and spectral unmixing. This topical collection is focused on the synthesis of UCNPs with new compositions/structures, tunable fluorescence emission and improved fluorescence intensity, and use of these nanoparticles for biodetection and bioimaging, both in-vitro and in-vivo.

Editors

  • Yong Zhang

    Yong Zhang is a Provost’s Chair Professor in Department of Biomedical Engineering, National University of Singapore (NUS). His current research interests include nanobiophotonics, nanomedicine, and microfluidic devices. He has authored over 200 research papers in international journals such as Nature Medicine, Nature Communications, PNAS, and Chemical Reviews, and has delivered more than 100 Plenary/keynote/invited talks in prestigious international conferences. He is a Fellow of Royal Society of Chemistry (FRSC) and a Highly Cited Researcher named by Clarivate Analytics. Website: www.zhangnuslab.com

Articles (9 in this collection)