Insight into Fungi-Mediated Nano-synthesis for Healthcare Applications: An Indian Perspective

Varma, Sanjana; Jaiswal, Neha; Shende, Rajnigandha A.; Chaudhari, Bhushan P.

doi:10.1007/978-981-16-3307-2_8

Sanjana Varma^4,5,
Neha Jaiswal^4,5,
Rajnigandha A. Shende^4,5 &
…
Bhushan P. Chaudhari^4,5

626 Accesses

Abstract

Nanotechnology comprises the synthesis, manipulation, and utilization of nanosize materials in several areas. The chemical, physical, and biological methods are the ways to synthesize nanoscale material of the desired characteristics. However, the drawbacks of physical and chemical means of synthesis have switched the attention of researchers towards the environment-friendly and non-toxic greener approach which mainly involves the use of plants, bacteria, fungi, and viruses. Myconanotechnology is an emerging branch of nanotechnology which has attracted the interest of many researchers around the world and especially in India due to the availability of the wide diversity of fungi. The remarkable countenances of fungi, mainly easy cultivation, tolerance to extreme conditions, as well as high yield of nanoparticles, make them more a preferred biosource for nano-synthesis. Fungi can form nanoparticles either intracellularly by using whole cells or extracellularly by using cell-free extracts. Physiological factors like temperature, pH, and time account for a vital role in controlling the morphology and dispersity of mycosynthesized nanoparticles. This chapter explains not only the various dimensions of fungi-mediated nano-synthesis but also the proposed mechanisms. Further, this chapter illustrates the role of different types of fungi-derived metal, metal oxide, and semiconductor nanoparticles in the biomedical field. In the Indian context, nanoparticles synthesized using fungi are being explored for antimicrobial, antifungal, anticancer, and larvicidal properties. Apart from this, their use in sensing is getting much attention. The role of such nanoparticles in drug delivery is also giving exciting results. Fungi-mediated formation of nanoparticles and its numerous applications in healthcare have opened up many unexplored areas in myconanotechnology all over the world including in India. Myconanotechnology can play a crucial role in giving solutions to pandemic situations for mankind. There is a need to take up this research from lab to clinic so that we can see the commercially viable nanoproducts in the healthcare sector of India and the world.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Chapter: USD 29.95; Price excludes VAT (USA)

eBook: USD 149.00; Price excludes VAT (USA)

Softcover Book: USD 199.99; Price excludes VAT (USA)

Hardcover Book: USD 199.99; Price excludes VAT (USA)

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

Abdeen S, Isaac RR, Geo S, Sornalekshmi S, Rose A, Praseetha PK (2013) Evaluation of antimicrobial activity of biosynthesized iron and silver nanoparticles using the fungi Fusarium oxysporum and Actinomycetes sp. on human pathogens. Nano Biomed Eng 5:39–45. https://doi.org/10.5101/nbe.v5i1.p39-45
Article CAS Google Scholar
Afreen RV, Ranganath E (2011) Synthesis of monodispersed silver nanoparticles by Rhizopus stolonifer and its antibacterial activity against MDR strains of Pseudomonas aeruginosa from burnt patients. Int J Environ Sci 1:1582–1592
CAS Google Scholar
Ahiwale SS, Bankar AV, Tagunde S, Kapadnis BP (2017) A bacteriophage mediated gold nanoparticles synthesis and their anti-biofilm activity. Indian J Microbiol 57:188–194. https://doi.org/10.1007/s12088-017-0640-x
Article CAS PubMed PubMed Central Google Scholar
Ahmad A, Mukherjee P, Senapati S, Mandal D, Khan MI, Kumar R, Sastry M (2003) Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium oxysporum. Colloids Surf B Biointerfaces 28:313–318. https://doi.org/10.1016/S0927-7765(02)00174-1
Article CAS Google Scholar
Ahmad A, Senapati S, Khan MI, Kumar R, Sastry M (2005) Extra-/intracellular biosynthesis of gold nanoparticles by an alkalotolerant fungus, Trichothecium sp. J Biomed Nanotechnol 1:47–53. https://doi.org/10.1166/jbn.2005.012
Article CAS Google Scholar
Ahmed S, Ahmad M, Swami BL, Ikram S (2016) A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: a green expertise. J Adv Res 7:17–28. https://doi.org/10.1016/j.jare.2015.02.007
Article CAS PubMed Google Scholar
Apte M, Sambre D, Gaikawad S, Joshi S, Bankar A, Kumar AR, Zinjarde S (2013) Psychrotrophic yeast Yarrowia lipolytica NCYC 789 mediates the synthesis of antimicrobial silver nanoparticles via cell-associated melanin. AMB Express 3:1–8. https://doi.org/10.1186/2191-0855-3-32
Article CAS Google Scholar
Arun G, Eyini M, Gunasekaran P (2014) Green synthesis of silver nanoparticles using the mushroom fungus Schizophyllum commune and its biomedical applications. Biotechnol Bioprocess Eng 19:1083–1090. https://doi.org/10.1007/s12257-014-0071-z
Article CAS Google Scholar
Asmathunisha N, Kathiresan K (2013) A review on biosynthesis of nanoparticles by marine organisms. Colloids Surf B Biointerfaces 103:283–287. https://doi.org/10.1016/j.colsurfb.2012.10.030
Article CAS PubMed Google Scholar
Aziz N, Pandey R, Barman I, Prasad R (2016) Leveraging the attributes of Mucor hiemalis-derived silver nanoparticles for a synergistic broad-spectrum antimicrobial platform. Front Microbiol 7:1–11. https://doi.org/10.3389/fmicb.2016.01984
Article Google Scholar
Aziz N, Faraz M, Sherwani MA, Fatma T, Prasad R (2019) Illuminating the anticancerous efficacy of a new fungal chassis for silver nanoparticle synthesis. Front Chem 7:1–11. https://doi.org/10.3389/fchem.2019.00065
Article CAS Google Scholar
Baker S, Harini BP, Rakshith D, Satish S (2013) Marine microbes: invisible nanofactories. J Pharm Res 6:383–388. https://doi.org/10.1016/j.jopr.2013.03.001
Article CAS Google Scholar
Balakumaran MD, Ramachandran R, Kalaichelvan PT (2015) Exploitation of endophytic fungus, Guignardia mangiferae for extracellular synthesis of silver nanoparticles and their in vitro biological activities. Microbiol Res 178:9–17. https://doi.org/10.1016/j.micres.2015.05.009
Article CAS PubMed Google Scholar
Bansal V, Poddar P, Ahmad A, Sastry M (2006) Room-temperature biosynthesis of ferroelectric barium titanate nanoparticles. J Am Chem Soc 128:11958–11963. https://doi.org/10.1021/ja063011m
Article CAS PubMed Google Scholar
Bansod S, Bonde S, Tiwari V, Bawaskar M, Deshmukh S, Gaikwad S, Gade A, Rai M (2013) Bioconjugation of gold and silver nanoparticles synthesized by Fusarium oxysporum and their use in rapid identification of Candida species by using bioconjugate-nano-polymerase chain reaction. J Biomed Nanotechnol 9:1962–1971. https://doi.org/10.1166/jbn.2013.1727
Article CAS PubMed Google Scholar
Banu AN, Balasubramanian C (2014) Myco-synthesis of silver nanoparticles using Beauveria bassiana against dengue vector, Aedes aegypti (Diptera: Culicidae). Parasitol Res 113:2869–2877. https://doi.org/10.1007/s00436-014-3948-z
Article PubMed Google Scholar
Basavaraja S, Balaji SD, Lagashetty A, Rajasab AH, Venkataraman A (2008) Extracellular biosynthesis of silver nanoparticles using the fungus Fusarium semitectum. Mater Res Bull 43:1164–1170. https://doi.org/10.1016/j.materresbull.2007.06.020
Article CAS Google Scholar
Baskar G, Chandhuru J, Fahad KS, Praveen AS, Bharathi R, Fyna S (2015) Mycological synthesis and characterization of silver nanoparticles by Aspergillus species. J Chem Pharm Res 7:300–306
CAS Google Scholar
Bhainsa KC, D’Souza SF (2006) Extracellular biosynthesis of silver nanoparticles using the fungus Aspergillus fumigatus. Colloids Surf B Biointerfaces 47:160–164. https://doi.org/10.1016/j.colsurfb.2005.11.026
Article CAS PubMed Google Scholar
Bhambure R, Bule M, Shaligram N, Kamat M, Singhal R (2009) Extracellular biosynthesis of gold nanoparticles using Aspergillus niger—its characterization and stability. Chem Eng Technol 32:1036–1041. https://doi.org/10.1002/ceat.200800647
Article CAS Google Scholar
Bharathidasan R, Panneerselvam A (2012) Biosynthesis and characterization of silver nanoparticles using endophytic fungi Aspergillus concius, Penicillium janthinellum and Phomosis sp. Int J Pharm Sci Res 3:3163–3169
CAS Google Scholar
Bharde A, Rautaray D, Bansal V, Ahmad A, Sarkar I, Yusuf SM, Sanyal M, Sastry M (2006) Extracellular biosynthesis of magnetite using fungi. Small 2:135–141. https://doi.org/10.1002/smll.200500180
Article CAS PubMed Google Scholar
Bhattacharjee S, Debnath G, Das AR, Saha AK, Das P (2017) Characterization of silver nanoparticles synthesized using an endophytic fungus, Penicillium oxalicum having potential antimicrobial activity. Adv Nat Sci Nanosci Nanotechnol 8:045008. https://doi.org/10.1088/2043-6254/aa84ec
Article CAS Google Scholar
Birla SS, Tiwari VV, Gade AK, Ingle AP, Yadav AP, Rai MK (2009) Fabrication of silver nanoparticles by Phoma glomerata and its combined effect against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. Lett Appl Microbiol 48:173–179. https://doi.org/10.1111/j.1472-765X.2008.02510.x
Article CAS PubMed Google Scholar
Brand-Williams W, Cuvelier ME, Berset C (1995) Use of a free radical method to evaluate antioxidant activity. LWT - Food Sci Technol 28:25–30. https://doi.org/10.1016/S0023-6438(95)80008-5
Article CAS Google Scholar
Chandra H, Kumari P, Bontempi E, Yadav S (2020) Medicinal plants: treasure trove for green synthesis of metallic nanoparticles and their biomedical applications. Biocatal Agric Biotechnol 24:101518. https://doi.org/10.1016/j.bcab.2020.101518
Article Google Scholar
Chandrappa CP, Govindappa M, Chandrasekar N, Sarkar S, Ooha S, Channabasava R (2016) Endophytic synthesis of silver chloride nanoparticles from Penicillium sp. of Calophyllum apetalum. Adv Nat Sci Nanosci Nanotechnol 7:025016. https://doi.org/10.1088/2043-6262/7/2/025016
Article CAS Google Scholar
Chauhan R, Reddy A, Abraham J (2015) Biosynthesis of silver and zinc oxide nanoparticles using Pichia fermentans JA2 and their antimicrobial property. Appl Nanosci 5:63–71. https://doi.org/10.1007/s13204-014-0292-7
Article CAS Google Scholar
Danagoudar A, Pratap GK, Shantaram M, Chatterjee B, Ghosh K, Kanade SR, Joshi CG (2020) Cancer cell specific cytotoxic potential of the silver nanoparticles synthesized using the endophytic fungus, Penicillium citrinum CGJ-C2. Mater Today Commun 25:101442. https://doi.org/10.1016/j.mtcomm.2020.101442
Article CAS Google Scholar
Das SK, Liang J, Schmidt M, Laffir F, Marsili E (2012) Biomineralization mechanism of gold by zygomycete fungus Rhizopous oryzae. ACS Nano 6:6165–6173. https://doi.org/10.1021/nn301502s
Article CAS PubMed Google Scholar
Devi LS, Joshi SR (2012) Antimicrobial and synergistic effects of silver nanoparticles synthesized using soil fungi of high altitudes of eastern Himalaya. Mycobiology 40:27–34. https://doi.org/10.5941/MYCO.2012.40.1.027
Article CAS PubMed PubMed Central Google Scholar
Devi LS, Joshi SR (2014) Evaluation of the antimicrobial potency of silver nanoparticles biosynthesized by using an endophytic fungus, Cryptosporiopsis ericae PS4. J Microbiol 52:667–674. https://doi.org/10.1007/s12275-014-4113-1
Article CAS PubMed Google Scholar
Devi LS, Joshi SR (2015) Ultrastructures of silver nanoparticles biosynthesized using endophytic fungi. J Microsc Ultrastruct 3:29–37. https://doi.org/10.1016/j.jmau.2014.10.004
Article CAS PubMed Google Scholar
Devi LS, Bareh DA, Joshi SR (2013) Studies on biosynthesis of antimicrobial silver nanoparticles using endophytic fungi isolated from the ethno-medicinal plant Gloriosa superba L. Proc Natl Acad Sci India B Biol Sci 84:1091–1099. https://doi.org/10.1007/s40011-013-0185-7
Article CAS Google Scholar
Ealias AM, Saravanakumar MP (2017) A review on the classification, characterisation, synthesis of nanoparticles and their application. IOP Conf Series Mater Sci Eng 263:032019. https://doi.org/10.1088/1757-899X/263/3/032019
Article Google Scholar
Fatima F, Bajpai P, Pathak N, Singh S, Priya S, Verma SR (2015) Antimicrobial and immunomodulatory efficacy of extracellularly synthesized silver and gold nanoparticles by a novel phosphate solubilizing fungus Bipolaris tetramera. BMC Microbiol 15:1–10. https://doi.org/10.1186/s12866-015-0391-y
Article CAS Google Scholar
Fayaz AM, Balaji K, Kalaichelvan PT, Venkatesan R (2009) Fungal based synthesis of silver nanoparticles—an effect of temperature on the size of particles. Colloids Surf B Biointerfaces 74:123–126. https://doi.org/10.1016/j.colsurfb.2009.07.002
Article CAS Google Scholar
Fayaz AM, Balaji K, Girilal M, Yadav R, Kalaichelvan PT, Venketesan R (2010) Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against gram-positive and gram-negative bacteria. Nanomedicine 6:103–109. https://doi.org/10.1016/j.nano.2009.04.006
Article CAS PubMed Google Scholar
Gade AK, Bonde P, Ingle AP, Marcato PD, Durán N, Rai MK (2008) Exploitation of Aspergillus niger for synthesis of silver nanoparticles. J Biobaased Mater Bioenergy 2:243–247. https://doi.org/10.1166/jbmb.2008.401
Article Google Scholar
Gade A, Ingle A, Whiteley C, Rai M (2010) Mycogenic metal nanoparticles: progress and applications. Biotechnol Lett 32:593–600. https://doi.org/10.1007/s10529-009-0197-9
Article CAS PubMed Google Scholar
Gahlawat G, Choudhury AR (2019) A review on the biosynthesis of metal and metal salt nanoparticles by microbes. RSC Adv 9:12944–12967. https://doi.org/10.1039/c8ra10483b
Article CAS PubMed Google Scholar
Gajbhiye M, Kesharwani J, Ingle A, Gade A, Rai M (2009) Fungus-mediated synthesis of silver nanoparticles and their activity against pathogenic fungi in combination with fluconazole. Nanomedicine 5:382–386. https://doi.org/10.1016/j.nano.2009.06.005
Article CAS PubMed Google Scholar
Govindappa M, Farheen H, Chandrappa CP, Channabasava R, Rai RV, Raghavendra VB (2016) Mycosynthesis of silver nanoparticles using extract of endophytic fungi, Penicillium species of Glycosmis mauritiana, and its antioxidant, antimicrobial, anti-inflammatory and tyrokinase inhibitory activity. Adv Nat Sci Nanosci Nanotechnol 7:035014. https://doi.org/10.1088/2043-6262/7/3/035014
Article CAS Google Scholar
Gudikandula K, Vadapally P, Charya MAS (2017) Biogenic synthesis of silver nanoparticles from white rot fungi: their characterization and antibacterial studies. OpenNano 2:64–78. https://doi.org/10.1016/j.onano.2017.07.002
Article Google Scholar
Gupta S, Bector S (2013) Biosynthesis of extracellular and intracellular gold nanoparticles by Aspergillus fumigatus and A. flavus. Anton Leeuw Int J Gen Mol Microbiol 103:1113–1123. https://doi.org/10.1007/s10482-013-9892-6
Article CAS Google Scholar
Gupta S, Sharma K, Sharma R (2012) Myconanotechnology and application of nanoparticles in biology. Recent Res Sci Technol 4:36–38
CAS Google Scholar
Hasan S (2015) A review on nanoparticles: their synthesis and types. Res J Recent Sci 4:1–3
Article Google Scholar
Hasan S, Gupta G (2012) Fungal biodiversity: evolution & distribution—a review. Int J Appl Res Stud 1:1–8
Google Scholar
Hulkoti NI, Taranath TC (2014) Biosynthesis of nanoparticles using microbes—a review. Colloids Surf B Biointerfaces 121:474–483. https://doi.org/10.1016/j.colsurfb.2014.05.027
Article CAS PubMed Google Scholar
Ingale AG, Chaudhari AN (2013) Biogenic synthesis of nanoparticles and potential applications: an eco-friendly approach. J Nanomed Nanotechol 4:1–7. https://doi.org/10.4172/2157-7439.1000165
Article CAS Google Scholar
Ingle A, Gade A, Pierrat S, Sonnichsen C, Rai M (2008) Mycosynthesis of silver nanoparticles using the fungus Fusarium acuminatum and its activity against some human pathogenic bacteria. Curr Nanosci 4:141–144. https://doi.org/10.2174/157341308784340804
Article CAS Google Scholar
Jaidev LR, Narasimha G (2010) Biointerfaces fungal mediated biosynthesis of silver nanoparticles, characterization and antimicrobial activity. Colloids Surf B Biointerfaces 81:430–433. https://doi.org/10.1016/j.colsurfb.2010.07.033
Article CAS PubMed Google Scholar
Jain N, Bhargava A, Majumdar S, Tarafdar JC, Panwar J (2011) Extracellular biosynthesis and characterization of silver nanoparticles using Aspergillus flavus NJP08: a mechanism perspective. Nanoscale 3:635–641. https://doi.org/10.1039/c0nr00656d
Article CAS PubMed Google Scholar
Karnani RL, Chowdhary A (2013) Biosynthesis of silver nanoparticle by eco-friendly method. Indian J Nanosci 1:25–31
Google Scholar
Kashyap PL, Kumar S, Srivastava AK, Sharma AK (2012) Myconanotechnology in agriculture: a perspective. World J Microbiol Biotechnol 29:191–207. https://doi.org/10.1007/s11274-012-1171-6
Article CAS PubMed Google Scholar
Kathiresan K, Manivannan S, Nabeel MA, Dhivya B (2009) Studies on silver nanoparticles synthesized by a marine fungus, Penicillium fellutanum isolated from coastal mangrove sediment. Colloids Surf B Biointerfaces 71:133–137. https://doi.org/10.1016/j.colsurfb.2009.01.016
Article CAS PubMed Google Scholar
Khan SA, Gambhir S, Ahmad A (2014) Extracellular biosynthesis of gadolinium oxide (Gd2O3) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol. Beilstein J Nanotechnol 5:249–257. https://doi.org/10.3762/bjnano.5.27
Article CAS PubMed PubMed Central Google Scholar
Khandel P, Shahi SK (2016) Microbes mediated synthesis of metal nanoparticles: current status and future prospects. Int J Nanomater Biostruct 6:1–24
Google Scholar
Koli SH, Mohite BV, Borase HP, Patil SV (2017) Monascus pigments mediated rapid green synthesis and characterization of gold nanoparticles with possible mechanism. J Cluster Sci 28:2719–2732. https://doi.org/10.1007/s10876-017-1254-5
Article CAS Google Scholar
Koli SH, Mohite BV, Suryawanshi RK, Borase HP, Patil SV (2018) Extracellular red Monascus pigment-mediated rapid one-step synthesis of silver nanoparticles and its application in biomedical and environment. Bioprocess Biosyst Eng 41:715–727. https://doi.org/10.1007/s00449-018-1905-4
Article CAS PubMed Google Scholar
Krishnan S, Narayan S, Chadha A (2016) Whole resting cells vs. cell free extracts of Candida parapsilosis ATCC 7330 for the synthesis of gold nanoparticles. AMB Express 6:1–15. https://doi.org/10.1186/s13568-016-0268-y
Article CAS Google Scholar
Kumar SA, Abyaneh MK, Gosavi SW, Kulkarni SK, Pasricha R, Ahmad A, Khan MI (2007) Nitrate reductase-mediated synthesis of silver nanoparticles from AgNO3. Biotechnol Lett 29:439–445. https://doi.org/10.1007/s10529-006-9256-7
Article CAS Google Scholar
Kumar S, Kumari P, Singh R (2020) Emerging nanomaterials for Cancer therapy. In: Shukla A (ed) Nanoparticles in medicine. Springer, Singapore, pp 25–54. https://doi.org/10.1007/978-981-13-8954-2_2
Chapter Google Scholar
Manjunath HM, Joshi CG, Raju NG (2014) Biogenic synthesis of silver nano particles using endophytic fungi Penicillium nodositatum and its antibacterial activity. J Chem Pharm Res 6:112–117
Google Scholar
Manjunath HM, Joshi CG, Raju NG (2016) Biofabrication of gold nanoparticles using marine endophytic fungus–Penicillium citrinum. IET Nanobiotechnol 11:40–44. https://doi.org/10.1049/iet-nbt.2016.0065
Article PubMed Central Google Scholar
Manjunath Hulikere M, Joshi CG, Ananda D, Poyya J, Kudva AK, Dhananjaya BL (2017) Biogenic synthesis of gold nanoparticles by marine endophytic fungus-Cladosporium cladosporioides isolated from seaweed and evaluation of their antioxidant and antimicrobial properties. Process Biochem 63:137–144. https://doi.org/10.1016/j.procbio.2017.09.008
Article CAS Google Scholar
Mazhar T, Shrivastava V, Tomar RS (2017) Green synthesis of bimetallic nanoparticles and its applications: a review. J Pharm Sci Res 9:102–110
CAS Google Scholar
Mazumdar H, Haloi N (2011) A study on biosynthesis of iron nanoparticles by Pleurotus sp. J Microbiol Biotechnol Res 1:39–49
CAS Google Scholar
Mishra A, Kumari M, Pandey S, Chaudhry V, Gupta KC, Nautiyal CS (2014) Biocatalytic and antimicrobial activities of gold nanoparticles synthesized by Trichoderma sp. Bioresour Technol 166:235–242. https://doi.org/10.1016/j.biortech.2014.04.085
Article CAS PubMed Google Scholar
Mittal AK, Chisti Y, Banerjee UC (2013) Synthesis of metallic nanoparticles using plant extracts. Biotechnol Adv 31:346–356. https://doi.org/10.1016/j.biotechadv.2013.01.003
Article CAS PubMed Google Scholar
Mohanpuria P, Rana NK, Yadav SK (2008) Biosynthesis of nanoparticles: technological concepts and future applications. J Nanoparticle Res 10:507–517. https://doi.org/10.1007/s11051-007-9275-x
Article CAS Google Scholar
Mukherjee S, Patra CR (2017) Biologically synthesized metal nanoparticles: recent advancement and future perspectives in cancer theranostics. Future Sci OA 3:FSO203
Article Google Scholar
Mukherjee P, Ahmad A, Mandal D, Senapati S, Sainkar SR, Khan MI, Ramani R, Parischa R, Ajayakumar PV, Alam M, Sastry M, Kumar R (2001) Bioreduction of AuCl4− ions by the fungus, Verticillium sp. and surface trapping of the gold nanoparticles formed. Angew Chem Int Ed 40:3585–3588. https://doi.org/10.1002/1521-3773(20011001)40:19<3585::AID-ANIE3585>3.0.CO;2-K
Article CAS Google Scholar
Mukherjee P, Senapati S, Mandal D, Ahmad A, Khan MI, Kumar R, Sastry M (2002) Extracellular synthesis of gold nanoparticles by the fungus Fusarium oxysporum. Chembiochem 3:461–463. https://doi.org/10.1002/1439-7633(20020503)3:5<461::AID-CBIC461>3.0.CO;2-X
Article CAS PubMed Google Scholar
Mukherjee P, Roy M, Mandal BP, Dey GK, Mukherjee PK, Ghatak J, Tyagi AK, Kale SP (2008) Green synthesis of highly stabilized nanocrystalline silver particles by a non-pathogenic and agriculturally important fungus T. asperellum. Nanotechnology 19:075103. https://doi.org/10.1088/0957-4484/19/7/075103
Article CAS PubMed Google Scholar
Mustafa S, Khan HM, Shukla I, Shujatullah F, Shahid M, AshfaqM AA (2011) Effect of ZnO nanoparticles on ESBL producing Escherichia coli & Klebsiella spp. Eastern J Med 16:253–257
Google Scholar
Nachiyar V, Sunkar S, Prakash P, Bavanilatha (2015) Biological synthesis of gold nanoparticles using endophytic fungi. Der Pharma Chem 7:31–38
CAS Google Scholar
Namasivayam SKR, Avimanyu (2011) Silver nanoparticle synthesis from Lecanicillium lecanii and evalutionary treatment on cotton fabrics by measuring their improved antibacterial activity with antibiotics against Staphylococcus aureus (ATCC 29213) and E. coli (ATCC 25922) strains. Int J Pharm Pharm Sci 3:190–195
Google Scholar
Narasimha G (2013) Virucidal properties of silver nanoparticles synthesized from white button mushrooms (Agaricus bisporus). Int J Nano Dimension 3:181–184. https://doi.org/10.7508/IJND.2012.03.002
Article CAS Google Scholar
Narayanan KB, Sakthivel N (2010) Biological synthesis of metal nanoparticles by microbes. Adv Colloid Interf Sci 156:1–13. https://doi.org/10.1016/j.cis.2010.02.001
Article CAS Google Scholar
Netala VR, Kotakadi VS, Bobbu P, Gaddam SA, Tartte V (2016a) Endophytic fungal isolate mediated biosynthesis of silver nanoparticles and their free radical scavenging activity and antimicrobial studies. 3 Biotech 6:1–9. https://doi.org/10.1007/s13205-016-0433-7
Article Google Scholar
Netala VR, Bethu MS, Pushpalatha B, Baki VB, Aishwarya S, Rao JV, Tartte V (2016b) Biogenesis of silver nanoparticles using endophytic fungus Pestalotiopsis microspora and evaluation of their antioxidant and anticancer activities. Int J Nanomed 11:5683–5696. https://doi.org/10.2147/IJN.S112857
Article CAS Google Scholar
Omar RA, Afreen S, Talreja N, Chauhan D, Ashfaq M, Srituravanich W (2019) Impact of nanomaterials on the microbial system. In: Prasad R (ed) Microbial nanobionics. Nanotechnology in the life sciences. Springer, Cham, pp 141–158. https://doi.org/10.1007/978-3-030-16383-9_6
Chapter Google Scholar
Patel S, Singh D, Srivastava S, Singh M, Shah K, Chauahn DN, Chauahn NS (2017) Nanoparticles as a platform for antimicrobial drug delivery. Adv Pharmacol Pharm 5:31–43. https://doi.org/10.13189/app.2017.050301
Article CAS Google Scholar
Popli D, Anil V, Subramanyam AB, Namratha MN, Ranjitha VR, Rao SN, Rai RV, Govindappa M (2018) Endophyte fungi, Cladosporium species-mediated synthesis of silver nanoparticles possessing in vitro antioxidant, anti-diabetic and anti-Alzheimer activity. Artif Cells Nanomed Biotechnol 46:676–683. https://doi.org/10.1080/21691401.2018.1434188
Article CAS PubMed Google Scholar
Raheman F, Deshmukh S, Ingle A, Gade A, Rai M (2011) Silver nanoparticles: novel antimicrobial agent synthesized from an endophytic fungus Pestalotia sp. isolated from leaves of Syzygium cumini (L). Nano Biomed Eng 3:174–178. https://doi.org/10.5101/nbe.v3i3.p174-178
Article CAS Google Scholar
Rajakumar G, Rahuman AA, Roopan SM, Khanna VG, Elango G, Kamaraj C, Zahir AA, Velayutham K (2012) Fungus-mediated biosynthesis and characterization of TiO₂ nanoparticles and their activity against pathogenic bacteria. Spectrochim Acta A Mol Biomol Spectrosc 91:23–29. https://doi.org/10.1016/j.saa.2012.01.011
Article CAS PubMed Google Scholar
Ramalingmam P, Muthukrishnan S, Thangaraj P (2015) Biosynthesis of silver nanoparticles using an endophytic fungus, Curvularia lunata and its antimicrobial potential. J Nanosci Nanoeng 1:241–247
Google Scholar
Saha S, Sarkar J, Chattopadhyay D, Patra S, Chakraborty A, Acharya K (2010) Production of silver nanoparticles by a phytopathogenic fungus Bipolaris nodulosa and its antimicrobial activity. Dig J Nanomater Biostruct 5:887–895
Google Scholar
Salunkhe RB, Patil SV, Patil CD, Salunke BK (2011) Larvicidal potential of silver nanoparticles synthesized using fungus Cochliobolus lunatus against Aedes aegypti (Linnaeus, 1762) and Anopheles stephensi Liston (Diptera; Culicidae). Parasitol Res 109:823–831. https://doi.org/10.1007/s00436-011-2328-1
Article PubMed Google Scholar
Sandana Mala JG, Rose C (2014) Facile production of ZnS quantum dot nanoparticles by Saccharomyces cerevisiae MTCC 2918. J Biotechnol 170:73–78. https://doi.org/10.1016/j.jbiotec.2013.11.017
Article CAS PubMed Google Scholar
Sanghi R, Verma P (2009a) A facile green extracellular biosynthesis of CdS nanoparticles by immobilized fungus. Chem Eng J 155:886–891. https://doi.org/10.1016/j.cej.2009.08.006
Article CAS Google Scholar
Sanghi R, Verma P (2009b) Biomimetic synthesis and characterisation of protein capped silver nanoparticles. Bioresour Technol 100:501–504. https://doi.org/10.1016/j.biortech.2008.05.048
Article CAS PubMed Google Scholar
Sastry M, Ahmad A, Khan MI, Kumar R (2003) Biosynthesis of metal nanoparticles using fungi and actinomycete. Curr Sci 85:162–170
CAS Google Scholar
Sawle BD, Salimath B, Deshpande R, Bedre MD, Prabhakar BK, Venkataraman A (2008) Biosynthesis and stabilization of Au and Au-Ag alloy nanoparticles by fungus, Fusarium semitectum. Sci Technol Adv Mater 9:035012. https://doi.org/10.1088/1468-6996/9/3/035012
Article CAS Google Scholar
Saxena J, Sharma MM, Gupta S, Singh A (2014) Emerging role of fungi in nanoparticle synthesis and their applications. World J Pharm Sci 3:1586–1613
Google Scholar
Selvakumar R, Seethalakshmi N, Thavamani P, Naidu R, Megharaj M (2014) Recent advances in the synthesis of inorganic nano/microstructures using microbial biotemplates and their applications. RSC Adv 4:52156–52169. https://doi.org/10.1039/c4ra07903e
Article CAS Google Scholar
Seshadri S, Saranya K, Kowshik M (2011) Green synthesis of lead sulfide nanoparticles by the lead resistant marine yeast, Rhodosporidium diobovatum. Biotechnol Prog 27:1464–1469. https://doi.org/10.1002/btpr.651
Article CAS PubMed Google Scholar
Shankar SS, Ahmad A, Pasricha R, Sastry M (2003) Bioreduction of chloroaurate ions by geranium leaves and its endophytic fungus yields gold nanoparticles of different shapes. J Mater Chem 13:1822–1826. https://doi.org/10.1039/b303808b
Article CAS Google Scholar
Singara Charya MA (2015) Fungi: an overview. In: Bahadur B, Venkat Rajam M, Sahijram L, Krishnamurthy K (eds) Plant biology and biotechnology. Springer, New Delhi, pp 197–215. https://doi.org/10.1007/978-81-322-2286-6_7
Chapter Google Scholar
Singh D, Rathod V, Ninganagouda S, Hiremath J, Singh AK, Mathew J (2014) Optimization and characterization of silver nanoparticle by endophytic fungi Penicillium sp. isolated from Curcuma longa (turmeric) and application studies against MDR E. coli and S. aureus. Bioinorg Chem Appl 2014:1–8. https://doi.org/10.1155/2014/408021
Article CAS Google Scholar
Singh AK, Rathod V, Singh D, Ninganagouda S, Kulkarni P, Mathew J, Haq MU (2015) Bioactive silver nanoparticles from endophytic fungus Fusarium sp. isolated from an ethanomedicinal plant Withania somnifera (Ashwagandha) and its antibacterial activity. Int J Nanomater Biostruct 5:15–19
Google Scholar
Singh DK, Kumar J, Sharma VK, Verma SK, Singh A, Kumari P, Kharwar RN (2017a) Mycosynthesis of bactericidal silver and polymorphic gold nanoparticles: physicochemical variation effects and mechanism. Nanomedicine 13:191–207. https://doi.org/10.2217/nnm-2017-0235
Article CAS PubMed Google Scholar
Singh T, Jyoti K, Patnaik A, Singh A, Chauhan R, Chandel SS (2017b) Biosynthesis, characterization and antibacterial activity of silver nanoparticles using an endophytic fungal supernatant of Raphanus sativus. J Genet Eng Biotechnol 15:31–39. https://doi.org/10.1016/j.jgeb.2017.04.005
Article PubMed PubMed Central Google Scholar
Soni N, Prakash S (2012a) Fungal-mediated nano silver: an effective adulticide against mosquito. Parasitol Res 111:2091–2098. https://doi.org/10.1007/s00436-012-3056-x
Article PubMed Google Scholar
Soni N, Prakash S (2012b) Synthesis of gold nanoparticles by the fungus Aspergillus niger and its efficacy against mosquito larvae. Rep Parasitol 2012:1–7. https://doi.org/10.2147/rip.s29033
Article Google Scholar
Sri S, Rajagopal K (2016) Isolation and identification of thermo tolerant endophytic fungi from Melia dubia and synthesis of zinc nano particles. Int J Nanosci Nanotechnol 7:99–112
Google Scholar
Sundaramoorthi C, Kalaivani M, Mathews DM, Palanisamy S, Kalaiselvan V, Rajasekaran A (2009) Biosynthesis of silver nanoparticles from Aspergillus niger and evaluation of its wound healing activity in experimental rat model. Int J PharmTech Res 1:1523–1529
CAS Google Scholar
Syed A, Ahmad A (2012) Extracellular biosynthesis of platinum nanoparticles using the fungus Fusarium oxysporum. Colloids Surf B Biointerfaces 97:27–31. https://doi.org/10.1016/j.colsurfb.2012.03.026
Article CAS PubMed Google Scholar
Talie MD, Wani AH, Ahmad N, Bhat MY, War JM (2020) Green synthesis of silver nanoparticles (Agnps) using Helvella Leucopus Pers. and their antimycotic activity against fungi causing fungal rot of apple. Asian J Pharm Clin Res 13:161–165. https://doi.org/10.22159/ajpcr.2020.v13i4.37024
Article CAS Google Scholar
Thakkar KN, Mhatre SS, Parikh RY (2010) Biological synthesis of metallic nanoparticles. Nanomedicine 6:257–262. https://doi.org/10.1016/j.nano.2009.07.002
Article CAS PubMed Google Scholar
Thirumurugan G, Veni VS, Ramachandran S, Rao JVLNS, Dhanaraju MD (2011) Superior wound healing effect of topically delivered silver nanoparticle formulation using eco-friendly potato plant pathogenic fungus: synthesis and characterization. J Biomed Nanotechnol 7:659–666. https://doi.org/10.1166/jbn.2011.1336
Article CAS PubMed Google Scholar
Tripathi RM, Gupta RK, Singh P, Bhadwal AS, Shrivastav A, Kumar N, Shrivastav BR (2014) Ultra-sensitive detection of mercury(II) ions in water sample using gold nanoparticles synthesized by Trichoderma harzianum and their mechanistic approach. Sensors Actuators B Chem 204:637–646. https://doi.org/10.1016/j.snb.2014.08.015
Article CAS Google Scholar
Uddandarao P, Balakrishnan RM (2016) ZnS semiconductor quantum dots production by an endophytic fungus Aspergillus flavus. Mater Sci Eng B 207:26–32. https://doi.org/10.1016/j.mseb.2016.01.013
Article CAS Google Scholar
Uddandarao P, Balakrishnan RM (2017) Thermal and optical characterization of biologically synthesized ZnS nanoparticles synthesized from an endophytic fungus Aspergillus flavus: a colorimetric probe in metal detection. Spectrochim Acta A Mol Biomol Spectrosc 175:200–207. https://doi.org/10.1016/j.saa.2016.12.021
Article CAS PubMed Google Scholar
Uddandarao P, Balakrishnan RM, Ashok A, Swarup S, Sinha P (2019) Bioinspired ZnS:Gd nanoparticles synthesized from an endophytic fungi Aspergillus flavus for fluorescence-based metal detection. Biomimetics 4:1–10. https://doi.org/10.3390/biomimetics4010011
Article CAS Google Scholar
Vala AK (2014) Intra-and extracellular biosynthesis of gold nanoparticles by a marine-derived fungus Rhizopus oryzae. Synth React Inorg Metal Org Nano-Metal Chem 44:1243–1246. https://doi.org/10.1080/15533174.2013.799492
Article CAS Google Scholar
Vala AK, Shah S (2012) Rapid synthesis of silver nanoparticles by a marine-derived fungus Aspergillus niger and their antimicrobial potentials. Int J Nanosci Nanotechnol 8:197–206
Google Scholar
Velusamy P, Kumar GV, Jeyanthi V, Das J, Pachaiappan R (2016) Bio-inspired green nanoparticles: synthesis, mechanism, and antibacterial application. Toxicol Res 32:95–102
Article CAS Google Scholar
Verma VC, Kharwar RN, Gange AC (2010) Biosynthesis of antimicrobial silver nanoparticles by the endophytic fungus Aspergillus clavatus. Nanomedicine 5:33–40. https://doi.org/10.2217/NNM.09.77
Article CAS PubMed Google Scholar
Verma VC, Singh SK, SolankiR PS (2011) Biofabrication of anisotropic gold nanotriangles using extract of endophytic Aspergillus clavatus as a dual functional reductant and stabilizer. Nanoscale Res Lett 6:1–7. https://doi.org/10.1007/s11671-010-9743-6
Article CAS Google Scholar
Vijayan S, Divya K, George TK, Jisha MS (2016) Biogenic synthesis of silver nanoparticles using endophytic fungi Fusarium oxysporum isolated from Withania somnifera (L.), its antibacterial and cytotoxic activity. J Bionanosci 10:369–376. https://doi.org/10.1166/jbns.2016.1390
Article CAS Google Scholar
Vijayanandan AS, Balakrishnan RM (2018) Biosynthesis of cobalt oxide nanoparticles using endophytic fungus Aspergillus nidulans. J Environ Manag 218:442–450. https://doi.org/10.1016/j.jenvman.2018.04.032
Article CAS Google Scholar
Yadav A, Kon K, Kratosova G, Duran N, Ingle AP, Rai M (2015) Fungi as an efficient mycosystem for the synthesis of metal nanoparticles: progress and key aspects of research. Biotechnol Lett 37:2099–2120. https://doi.org/10.1007/s10529-015-1901-6
Article CAS PubMed Google Scholar

Download references

Author information

Authors and Affiliations

Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India
Sanjana Varma, Neha Jaiswal, Rajnigandha A. Shende & Bhushan P. Chaudhari
Biochemical Sciences Division, CSIR-National Chemical Laboratory, Pashan, Pune, India
Sanjana Varma, Neha Jaiswal, Rajnigandha A. Shende & Bhushan P. Chaudhari

Authors

Sanjana Varma
View author publications
You can also search for this author in PubMed Google Scholar
Neha Jaiswal
View author publications
You can also search for this author in PubMed Google Scholar
Rajnigandha A. Shende
View author publications
You can also search for this author in PubMed Google Scholar
Bhushan P. Chaudhari
View author publications
You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Bhushan P. Chaudhari .

Editor information

Editors and Affiliations

Division of Biological Sciences and Engineering, Netaji Subhas University of Technology, New Delhi, Delhi, India
Tulasi Satyanarayana
TERI-Deakin Nano Biotechnology Centre, The Energy and Resources Institute, New Delhi, India
Sunil Kumar Deshmukh
Director, Greenvention Biotech Pvt. Ltd., Uruli Kanchan, Maharashtra, India
Mukund V. Deshpande

Rights and permissions

Reprints and permissions

Copyright information

About this chapter

Cite this chapter

Varma, S., Jaiswal, N., Shende, R.A., Chaudhari, B.P. (2021). Insight into Fungi-Mediated Nano-synthesis for Healthcare Applications: An Indian Perspective. In: Satyanarayana, T., Deshmukh, S.K., Deshpande, M.V. (eds) Progress in Mycology. Springer, Singapore. https://doi.org/10.1007/978-981-16-3307-2_8

Download citation

DOI: https://doi.org/10.1007/978-981-16-3307-2_8
Published: 22 February 2022
Publisher Name: Springer, Singapore
Print ISBN: 978-981-16-3306-5
Online ISBN: 978-981-16-3307-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)

Publish with us

Policies and ethics