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Urogenital Tract

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Regenerative Medicine - from Protocol to Patient

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Abstract

Urogenital tract diseases with potential relevance for regenerative therapies affect different parts of the urogenital system. Domains of urogenital medicine are the upper and lower urinary tract, urinary incontinence, erectile function and pelvic organ prolapse. Thereby congenital, traumatic, oncologic, inflammatory, or iatrogenic causes may be responsible for physical and psychological impairment of affected humans. Regenerative medicine in urology consists of cell-based regenerative therapy, the application of different scaffolds and increasingly a combination of both regenerative principles. A widespread collection of preclinical studies in all fields of interest resulted in a considerably smaller quantity of clinical studies. However, only few established applications have been introduced into clinical routine. Particularly potentially poor clinical study arrangement and lacking or deficient cross-national counselling may be responsible for the imbalance of excellent fundamental research and legally approved regenerative therapies. Currently increasing cooperation and growing insight into stem cell mechanisms will offer the possibility of extended success in the future.

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  1. Department of Urology, University Hospital of Tuebingen, Tuebingen, Germany

    B. Amend, W. K. Aicher & Arnulf Stenzl

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  1. Department of Cardiac Surgery and Refere, University of Rostock, Rostock, Mecklenburg-Vorpomm., Germany

    Gustav Steinhoff

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Amend, B., Aicher, W.K., Stenzl, A. (2016). Urogenital Tract. In: Steinhoff, G. (eds) Regenerative Medicine - from Protocol to Patient. Springer, Cham. https://doi.org/10.1007/978-3-319-28386-9_8

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