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The Role of Instrumental Learning in Behavioral Tolerance to Drugs

  • Chapter
Psychoactive Drugs

Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

Historically, the term “behavioral tolerance” has had two meanings. When used descriptively, it refers to tolerance that develops to a behavioral effect of a drug (cf. Corfield-Sumner and Stolerman, 1978; Schuster, 1978). This use of the term carries no implications for underlying mechanisms; i.e., tolerance may result from the same mechanisms that alter a physiological or pharmacological effect. However, the term has also been used mechanistically to mean that tolerance is mediated by a behavioral compensation for the initial effects of a drug (cf. Dews, 1978; Ferraro, 1978; Demellweek and Goudie, 1983b). This chapter deals with the second use of the term. More specifically, it considers the possibility that, under appropriate circumstances, tolerance is mediated by instrumental learning.

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  1. David L. Wolgin
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  1. Department of Psychology, University of Liverpool, Liverpool, UK

    Andrew J. Goudie

  2. Department of Pharmacology, Texas College of Osteopathic Medicine, Fort Worth, Texas, USA

    Michael W. Emmett-Oglesby

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Wolgin, D.L. (1989). The Role of Instrumental Learning in Behavioral Tolerance to Drugs. In: Goudie, A.J., Emmett-Oglesby, M.W. (eds) Psychoactive Drugs. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-464-1_2

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