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The Enzyme Catalysis Process

Energetics, Mechanism and Dynamics

  • Alan Cooper
  • Julien L. Houben
  • Lisa C. Chien

Part of the Progress in Mathematics book series (NSSA)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Introductory Lectures

    1. Front Matter
      Pages 1-1
    2. Alan Cooper, Julien L. Houben
      Pages 11-21
  3. Protein Structure, Spectroscopy and Dynamics

    1. Front Matter
      Pages 23-23
    2. R. L. Somorjai
      Pages 25-40
    3. R. L. Somorjai
      Pages 41-53
    4. Francois Fillaux
      Pages 93-102
    5. Alan Cooper, David T. F. Dryden
      Pages 159-171
    6. John A. Rupley, Giorgio Careri
      Pages 223-234
    7. John A. Rupley, Giorgio Careri
      Pages 235-246
    8. F. Wanderlingh, R. Giordano
      Pages 247-271
  4. Reactivity and Catalysis

  5. Practical and Industrial Applications

  6. Back Matter
    Pages 477-493

About this book

Introduction

This volume represents the proceedings of a NATO Advanced Studies Instituteheld near Barga (Italy), July 11-23, 1988, involving over 90 participants from more than twelve countries of Europe, North America and elsewhere. It was not our intention at this meeting to present a complete up-to-the-minute review of current research in enzyme catalysis but t·ather, in accord wi th the intended spiri t of NATO ASis, to gi ve an opportunity for advanced students and researchers in a wide variety of disciplines to meet tagether and study the problern from different points of view. Hence the lectures cover topics rauging from the purely theoretical aspects of chemical reaction kinetics in condensed matter through practical experimental approaches to enzyme structure, dynamics and mechanism, including the new experimental opportunities arising from genetic engineering techniques. Our approachwas unashamedly physical, both because the more biochemical aspects of enzymology are amply covered elsewhere and because progress in our understanding and application of the molecular basis of enzymic processes must ultimately come from advances in physical knowledge. We tried to cover as wide a spectrum as possible, and succeeded in gathering an expert and enthusiastic team of speakers, but there . are some inevitable omissions. In particular, and with hindsight, our discussions might have been enriched by more detailed coverage of general aspects of chemical catalysis - but readers requiring this background should find adequate references herein.

Keywords

catalysis Chemical reaction enzyme enzymes kinetics reaction kinetics

Editors and affiliations

  • Alan Cooper
    • 1
  • Julien L. Houben
    • 2
  • Lisa C. Chien
    • 2
  1. 1.Dept. of ChemistryUniversity of GlasgowGlasgowScotland, UK
  2. 2.Istituto di Chimica Quantistica ed Energetica MolecolareCNRPisaItaly

Bibliographic information