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Proteins: Interactions and Dynamics

  • R. L. Somorjai
Part of the Progress in Mathematics book series (NSSA)

Abstract

Enzymes (proteins) have characteristic, stable three-dimensional structures. Despite their apparently miraculous feats of discrimination and catalytic power, enzymes are stabilized and functionally primed by the same physical forces that operate on less glamorous systems such as liquids and solids. Nevertheless, it is important to characterize these forces as they appear to act in proteins since first-principle quantum mechanical calculations on such large systems are entirely impractical. We are faced with inevitable approximations and simplifications when attempting to calculate protein structure and dynamics.

Keywords

Free Energy Difference Peptide Group Nonbonded Interaction Relative Free Energy Nonpolar Solute 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • R. L. Somorjai
    • 1
  1. 1.Division of Biological SciencesNational Research Council of CanadaOttawaCanada

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