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Potassium Channels in Cardiovascular Biology

  • Stephen L. Archer
  • Nancy J. Rusch

Table of contents

  1. Front Matter
    Pages i-xlv
  2. Molecular Biology of Potassium Channels

    1. Front Matter
      Pages 1-1
    2. Warren J. Gallin, Andrew N. Spencer
      Pages 3-16
    3. Pratap Meera, Martin Wallner, Ligia Toro
      Pages 49-70
    4. S. L. Shyng, A. N. Lopatin, C. G. Nichols
      Pages 71-88
  3. Potassium Channel Expression and Function

    1. Front Matter
      Pages 89-89
    2. Robert O. Koch, Maria Trieb, Alexandra Koschak, Siegmund G. Wanner, Kathryn M. Gauthier, Nancy J. Rusch et al.
      Pages 91-102
    3. Michael J. Morales, Mulugu V. Brahmajothi, Donald L. Campbell, Harold C. Strauss
      Pages 103-118
    4. James S. Trimmer, Kenneth J. Rhodes
      Pages 163-175
  4. Pharmacology of Potassium Channels

    1. Front Matter
      Pages 193-193
    2. Brian Robertson
      Pages 195-217
    3. Maria L. Garcia, Gregory J. Kaczorowski
      Pages 219-234
    4. Eric Blanc, Hervé Darbon
      Pages 235-256
    5. Andre Terzic, Michel Vivaudou
      Pages 257-277
  5. Potassium Channels in the Heart

    1. Front Matter
      Pages 279-279
    2. B. M. Heath, X. Wehrens, R. S. Kass
      Pages 281-296
    3. Joanne T. Hulme, Jeffrey R. Martens, Ricardo A. Navarro-Polanco, Atsushi Nishiyama, Michael M. Tamkun
      Pages 337-362
    4. Christopher Parker, David Fedida
      Pages 387-426
    5. Fuhua Chen, Thomas S. Klitzner
      Pages 427-439
  6. Potassium Channels in Vascular Smooth Muscle

    1. Front Matter
      Pages 441-441
    2. D. J. Beech, A. Cheong, R. Flemming, C. Guibert, S. Z. Xu
      Pages 457-483
    3. George C. Wellman, Mark T. Nelson
      Pages 523-542
    4. James D. Stockand, Steven C. Sansom
      Pages 571-589
    5. Helen L. Reeve, David N. Cornfield
      Pages 617-636
  7. Potassium Channels in the Endothelium

  8. Potassium Channels in Cardiac Disease

    1. Front Matter
      Pages 725-725
    2. Albert J. D’ Alonzo, Paul C. Levesque, Michael A. Blanar
      Pages 727-752
    3. Martin Tristani-Firouzi, Michael C. Sanguinetti
      Pages 753-772
    4. Koichi Takimoto, Edwin S. Levitan
      Pages 773-783
  9. Potassium Channels in Vascular Disease

    1. Front Matter
      Pages 819-819
    2. Evangelos D. Michelakis, E. Kenneth Weir
      Pages 837-852

About this book

Introduction

Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K+ channels determine or modulate many functions of vascular smooth muscle, endothelial and inflammatory cells, and thus are central to regulation of arterial tone and control of cell proliferation. They are also promising targets for antihypertensive treatments with drugs which open and close specific types of K+ channels, making for an active field of research. With their ability to control vascular tone, voltage-gated K+ channels play a significant role in both pulmonary and systemic hypertension as well as in cardiac arrhythmias. This book will highlight the latest discoveries by leading researchers pertaining to the role of K+ channels in the heart and blood vessels in normal physiology and a variety of disease states.

Keywords

blood vessel cardiovascular cells endothelium hypertension physiology proteins smooth muscle

Editors and affiliations

  • Stephen L. Archer
    • 1
  • Nancy J. Rusch
    • 2
  1. 1.Walter McKenzie Health Science CentreUniversity of Alberta HospitalEdmontonCanada
  2. 2.Medical College of WisconsinMilwaukeeUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4615-1303-2
  • Copyright Information Kluwer Academic / Plenum Publishers, New York 2001
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4613-5487-1
  • Online ISBN 978-1-4615-1303-2
  • Buy this book on publisher's site