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Palgrave Macmillan

Therapeutic Monoclonal Antibodies

  • Book
  • © 1990

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Editors:
  1. Carl A. K. Borrebaeck
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  2. James W. Larrick
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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xiii
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  2. The Use of In Vitro Immunization, Cloning of Variable Regions, and SCID Mice for the Production of Human Monoclonal Antibodies

    • Carl A. K. Borrebaeck, Lena Danielsson, Mats Ohlin, Jonas Carlsson, Roland Carlsson
    Pages 1-15

  3. Construction of Recombinant Therapeutic Monoclonal Antibodies

    • James W. Larrick, Jorge V. Gavilondo, Maria J. Coloma, Kirk E. Fry
    Pages 17-34

  4. Antibody-Mediated Cancer Diagnosis and Therapy

    • Jenny M. Bator, Christopher L. Reading
    Pages 35-56

  5. Current Status and Future Perspectives of Chemoimmunoconjugates for the Treatment of Cancer

    • Ralph A. Reisfeld, Martin Schrappe
    Pages 57-73

  6. Gangliosides as Targets for Monoclonal Antibody Therapy of Cancer

    • Reiko F. Irie, Mepur H. Ravindranath
    Pages 75-94

  7. Mouse Antibodies to Carcinomas

    • Karl Erik Hellström, Ingegerd Hellström
    Pages 95-108

  8. Therapeutic Implication of Monoclonal Antibodies against Multidrug-Resistant Tumor Cells

    • Takashi Tsuruo, Hirofumi Hamada
    Pages 109-126

  9. Radioimmunotherapy with 90Yttrium—Anti-Idiotype Monoclonal Antibody

    • Barbara A. Parker, Samuel E. Halpern, Ivor Royston
    Pages 127-141

  10. Immunoconjugates of a Protein Synthesis-Inhibiting Drug

    • Alton C. Morgan Jr., F. Taha Comezoglu, Ron Manger, Bruce B. Jarvis, Paul G. Abrams, Gowsala Sivam
    Pages 143-158

  11. Human Monoclonal Anti-Idiotypic Antibodies against a Murine Monoclonal Antibody (Mab17-1A) as an Anti-Tumor Vaccine

    • Michael Steinitz, Sara Tamir, Jan-Erik Frödin, Håkan Mellstedt
    Pages 159-171

  12. Uses of Human Monoclonal Antibodies to Human Cytomegalovirus and Varicella-Zoster Virus

    • Steven K. H. Foung, Peggy A. Bradshaw, David Emanuel
    Pages 173-185

  13. Development of a Human Monoclonal Antibody against Cytomegalovirus with the Aim of a Passive Immunotherapy

    • Yasuhiko Masuho, Yoh-Ichi Matsumoto, Tohru Sugano, Takami Tomiyama, Satoshi Sasaki, Tamotsu Koyama
    Pages 187-207

  14. Characterization of Human Anti-Cytomegalovirus Monoclonal Antibodies

    • Paul H. Ehrlich, Lars Östberg
    Pages 209-222

  15. Immunoprotective Capacities of Human and Murine Monoclonal Antibodies Recognizing Serotype-Specific and Common Determinants of Gram-negative Bacteria

    • Alois B. Lang, Urs Bruderer, Emil Fuerer, James W. Larrick, Stanley J. Cryz Jr.
    Pages 223-234

  16. Preclinical Development of Xomen™-E5

    • Ada H. C. Kung, Elizabeth A. Saria, Nancy Wedel, Patrick W. Trown
    Pages 235-251

  17. Randomized Placebo-controlled Study of E5 Monoclonal Antiendotoxin Antibody

    • Kenneth Gorelick, Patrick J. Scannon, John Hannigan, Nancy Wedel, Samuel K. Ackerman
    Pages 253-261

  18. Human Monoclonal Antibodies against Human Red Blood Cells

    • Phillippe Rouger, D. Goossens
    Pages 263-286

  19. CD7 Monoclonal Antibodies

    • Peter Amlot, Salvatore Cammisuli
    Pages 287-302

  20. Large-Scale Production of Monoclonal Antibodies

    • Cristina Glad, Inge Nilsson
    Pages 303-319
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Keywords

About this book

A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.

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