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Chirality Transfer in Supramolecular Co-assembled Fibrous Material Enabling the Visual Recognition of Sucrose

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Abstract

Molecular recognition of simple sugars is crucial due to their essential roles in most living organisms. However, it remains extremely challenging to achieve a visual recognition of simple sugars like sucrose in water media under physiological conditions. In this article, the visual recognition of sucrose is accomplished by a chiral supramolecular hydrogel formation through the co-assembly of a two-component fibrous solution (l-phenylalanine based gelator co-diaminopyridine, LDAP) and sucrose. H-bonding between the amino group of LDAP and the hydroxyl group of sucrose facilitates the gelation by loading sucrose into the LDAP solution. The formed hydrogel showed an amplified inversion of circular dichroism (CD) signals as compared to the corresponding LDAP solution. In addition, the effective chirality transfer was accompanied by a bathochromic shift in UV–Vis and FL spectra of the gel. Such a simple and straightforward chiral co-assembled strategy to visually recognize sucrose will have the potential use of smart gelators in saccharides separation and proteomics to be further applied in medical diagnostics and cell imaging.

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Acknowledgements

This work was supported by the Innovation Program of Shanghai Municipal Education Commission (201701070002E00061), the NSFC (51833006, 51573092), Program for Professors of Special Appointment (Eastern) at the Shanghai Institutions of Higher Learning, Science and Technology Commission of Shanghai Municipality (STCSM, No. 19441903000, 19ZR1425400), and Shanghai Jiao Tong University Interdisciplinary (Biomedical Engineering) Research Fund (No. ZH2018QNA12).

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Authors and Affiliations

  1. State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiaotong University, Dongchuan Rd 800, Shanghai, 200240, China

    Nabila Mehwish, Xiaoqiu Dou, Changli Zhao & Chuanliang Feng

  2. State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu, 610065, China

    Qiang Fu

Authors
  1. Nabila Mehwish
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  2. Xiaoqiu Dou
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  3. Changli Zhao
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  4. Chuanliang Feng
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  5. Qiang Fu
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Correspondence to Xiaoqiu Dou or Chuanliang Feng.

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Mehwish, N., Dou, X., Zhao, C. et al. Chirality Transfer in Supramolecular Co-assembled Fibrous Material Enabling the Visual Recognition of Sucrose. Adv. Fiber Mater. 2, 204–211 (2020). https://doi.org/10.1007/s42765-020-00028-w

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