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Effects of Rice Bran Oil Enriched with n-3 PUFA on Liver and Serum Lipids in Rats

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Lipids

Abstract

Lipase-catalyzed interesterification was used to prepare different structured lipids (SL) from rice bran oil (RBO) by replacing some of the fatty acids with α-linolenic acid (ALA) from linseed oil (LSO) and n-3 long chain polyunsaturated fatty acids (PUFA) from cod liver oil (CLO). In one SL, the ALA content was 20% whereas in another the long chain n-3 PUFA content was 10%. Most of the n-3 PUFA were incorporated into the sn-1 and sn-3 positions of triacylglycerol. The influence of SL with RBO rich in ALA and EPA + DHA was studied on various lipid parameters in experimental animals. Rats fed RBO showed a decrease in total serum cholesterol by 10% when compared to groundnut oil (GNO). Similarly structured lipids with CLO and LSO significantly decreased total serum cholesterol by 19 and 22% respectively compared to rice bran oil. The serum TAGs level of rats fed SLs and blended oils were also significantly decreased by 14 and 17% respectively compared to RBO. Feeding of an n-3 PUFA rich diet resulted in the accumulation of long chain n-3 PUFA in various tissues and a reduction in the long chain n-6 PUFA. These studies indicate that the incorporation of ALA and EPA + DHA into RBO can offer health benefits.

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Acknowledgments

The authors thank the Director, CFTRI Mysore, for constant encouragement. Rajni Chopra expresses her gratitude and thanks to the University Grant Commission (UGC), New Delhi for awarding her a Senior Research Fellowship.

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Authors and Affiliations

  1. Department of Foods and Nutrition, Institute of Home Economics, University of Delhi, F-4, Hauz Khas Enclave, New Delhi, 110017, India

    Rajni Chopra

  2. Department of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore, 570020, India

    Kari Sambaiah

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  1. Rajni Chopra
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  2. Kari Sambaiah
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Correspondence to Kari Sambaiah.

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Chopra, R., Sambaiah, K. Effects of Rice Bran Oil Enriched with n-3 PUFA on Liver and Serum Lipids in Rats. Lipids 44, 37–46 (2009). https://doi.org/10.1007/s11745-008-3240-z

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  • DOI: https://doi.org/10.1007/s11745-008-3240-z

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