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Zinc Oxide Nanoparticles: Green Synthesis and Biomedical Applications

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Abstract

Nanoparticles refer to ultrafine particles with the particle size at nanoscale. When metals and metal oxides were synthesized at nanoscale, by their unique properties such as smaller particle size, high strength, reactivity, sensitivity, specificity and stability, they have established a wide variety of applications, and thus have gained popularity in various industries such as food, textile, cosmetic, automobile and pharmaceuticals. Silver, gold, copper, aluminium, nickel, iron, zinc oxide, titanium dioxide and copper oxide nanoparticles are few among them. This article presents a review on zinc oxide nanoparticles, its green synthesis methods and various applications in biomedical fields such as antibacterial, antifungal, anticancer, anti-inflammatory and wound healing.

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Acknowledgement

The authors acknowledge the financial support from Vinayaka Mission’s Research Foundation (Deemed to be University), Salem (Research Grant No: VMRF/SeedMoney/2020/VMKVEC-Salem/6).

Funding

The authors acknowledge the financial support from Vinayaka Mission’s Research Foundation (Deemed to be University), Salem (Research Grant No: VMRF/SeedMoney/2020/VMKVEC-Salem/6).

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Authors and Affiliations

  1. Department of Pharmaceutical Engineering, Vinayaka Mission’s Kirupananda Variyar Engineering College, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, 636308, India

    Sahana Sadhasivam, Megala Shanmugam, Pillai Divya Umamaheswaran & Anusuya Shanmugam

  2. Department of Chemistry, Vinayaka Mission’s Kirupananda Variyar Arts and Science College, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, 636308, India

    Anbazhagan Venkattappan

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  1. Sahana Sadhasivam
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  2. Megala Shanmugam
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  3. Pillai Divya Umamaheswaran
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  4. Anbazhagan Venkattappan
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  5. Anusuya Shanmugam
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Contributions

SS reviewed the literature, wrote sections on introduction, plant mediated and microbial mediated synthesis of ZnO NPs. MS reviewed the literature and wrote sections on antibacterial activity of ZnO NPs. PDU reviewed the literature and wrote sections on anti-inflammatory and anticancer activities of ZnO NPs. AV reviewed the literature and wrote sections on wound healing activity of ZnO NPs. AS reviewed the literature and wrote sections on antifungal activity of ZnO NPs. SS and AS conceived the manuscript. All the authors read and approved the manuscript.

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Correspondence to Anusuya Shanmugam.

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Sadhasivam, S., Shanmugam, M., Umamaheswaran, P.D. et al. Zinc Oxide Nanoparticles: Green Synthesis and Biomedical Applications. J Clust Sci 32, 1441–1455 (2021). https://doi.org/10.1007/s10876-020-01918-0

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