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Poly(Styrene Sulfonate)/Poly(Allylamine Hydrochloride) Encapsulation of TiO2 Nanoparticles Boosts Their Toxic and Repellent Activity Against Zika Virus Mosquito Vectors

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Abstract

Green fabricated nanoparticles often need to be encapsulated and stabilized, to ensure uniform dispersion in the aquatic environment and relevant larvicidal activity over time. However, recent research showed that nanoencapsulation processes led to a reduction of nanoparticle larvicidal efficacy. We used an extract of Argemone mexicana to reduce TiO2 nanoparticles, which were then capped with PSS/PAH (poly(styrene sulfonate)/poly(allylamine hydrochloride)). The toxic and repellent potential of the nanoparticles were compared to elucidate their potential effects against the Zika virus vector Aedes aegypti. Nanoparticles were characterized by biophysical methods including UV–Vis, EDX and FTIR spectroscopy, SEM, TEM, XRD and DLS analyses. In larvicidal and pupicidal experiments, TiO2 nanoparticles achieved LC90 values from 41.648 (larva I), to 71.74 ppm (pupa). Nanoencapsulated TiO2 achieved LC90 values from 39.16 (I), to 69.12 ppm (pupa). In adulticidal experiments, LC90 of TiO2 nanoparticles on Ae. aegypti was 10.31 ppm, while LC90 of nanoencapsulated TiO2 was 9.54 ppm. At 10 ppm, the repellency towards Ae. aegypti was 80.43% for TiO2 nanoparticles, and 88.04% for nanoencapsulated TiO2. This research firstly highlighted the promising potential of PSS/PAH encapsulation, leading to the production of highly effective titania nanostructures, if compared to titania nanoparticles synthesized with eco-friendly routes without further stabilization.

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Acknowledgements

The authors extend their appreciation to the International Scientific Partnership Program ISPP at King Saud University for funding this research work through ISPP# 0062. Dr. Anitha Jaganathan is grateful to the University Grant Commission (New Delhi, India), Project No. PDFSS-2014-15-SC-TAM-10125.

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Authors and Affiliations

  1. Division of Entomology, Department of Zoology, School of Life Sciences, Bharathiar University, Coimbatore, Tamil Nadu, 641046, India

    Kadarkarai Murugan, Anitha Jaganathan, Rajapandian Rajaganesh & Udaiyan Suresh

  2. Thiruvalluvar University, Serkkadu, Vellore, Tamil Nadu, 632115, India

    Kadarkarai Murugan & Jagan Madhavan

  3. Division of Biopesticides and Environmental Toxicology, Sri Paramakalyani Centre for Excellence in Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamil Nadu, 627412, India

    Sengottayan Senthil-Nathan

  4. Department of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore, 632115, India

    Aruliah Rajasekar

  5. Department of Chemical and Materials Engineering, National Central University, No. 300, Jhongli, Taoyuan, 32001, Taiwan

    Akon Higuchi

  6. Department of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia

    Suresh S. Kumar

  7. Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia

    Abdullah A. Alarfaj

  8. Department of Environmental Biology, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy

    Marcello Nicoletti

  9. School of Pharmacy, University of Camerino, Camerino, Italy

    Riccardo Petrelli, Loredana Cappellacci & Filippo Maggi

  10. Department of Agriculture, Food and Environment, University of Pisa, Via Del Borghetto 80, 56124, Pisa, Italy

    Giovanni Benelli

  11. The BioRobotics Institute, Sant’Anna School of Advanced Studies, Viale Rinaldo Piaggio 34, 56025, Pontedera, Italy

    Giovanni Benelli

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  1. Kadarkarai Murugan
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  4. Udaiyan Suresh
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Correspondence to Kadarkarai Murugan or Giovanni Benelli.

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Murugan, K., Jaganathan, A., Rajaganesh, R. et al. Poly(Styrene Sulfonate)/Poly(Allylamine Hydrochloride) Encapsulation of TiO2 Nanoparticles Boosts Their Toxic and Repellent Activity Against Zika Virus Mosquito Vectors. J Clust Sci 29, 27–39 (2018). https://doi.org/10.1007/s10876-017-1300-3

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  • DOI: https://doi.org/10.1007/s10876-017-1300-3

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