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Experimental Silica-based Bioceramic Composite Added with Nano-sized Bovine Hydroxyapatite: Synthesis and Characterization

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Abstract

Purpose

To produce an experimental dense silica-based bioceramic composite added with nano-sized hydroxyapatite (HA) for biomedical application and physicochemical/ microstructurally characterize varying the firing temperature and the amount of binder, polyvinyl butyral (PVB).

Methods

Fumed SiO2 and nano-sized HA powder from bovine bone were ball milled aiming the mixture of powders. Groups were divided into HA (3, 5 and 10%), and PVB (1.2 and 2.4 wt.%) addition, and sintering process (1100, 1200 and 1300 °C with a 4 h plateau). The materials were characterized by X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy analysis (EDX).

Results

The group fired at 1200 °C presented potentialized chemical bonds without the degradation of HA at XRD profile, based on its microstructural evolution. FTIR spectra shows the degradation of HA, with an increase of CO2 band and a loss of the calcium-phosphate bands as the temperature increases. The binder concentration showed no chemical changes in the material. 2.4 wt.% of PVB addition resulted in optimized compaction and a lower inclusion of pores or cracks, suggested by SEM images.

Conclusion

This study suggests that the match composition of SiO2 matrix with 5% of HA and 2.4 wt.% of PVB, sintered at 1200 °C, exhibit potentially superior properties to biomaterial applications.

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Data Availability

All data are presented in the manuscript.

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Acknowledgements

The authors are grateful for the support provided by São Paulo Research Foundation (FAPESP) and the Coordination for the Improvement of Higher Education Personnel (CAPES).

Funding

This research was funded by São Paulo Research Foundation (FAPESP), grant number 2018/23639-0 and the Coordination for the Improvement of Higher Education Personnel (CAPES - Finance Code 001).

Author information

Authors and Affiliations

  1. Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil

    Brunna Mota Ferrairo, Lucas José de Azevedo-Silva & José Henrique Rubo

  2. Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Vila Universitária, Bauru, São Paulo, 17012-901, Brazil

    Victor Mosquim, Luara Aline Pires & Ana Flávia Sanches Borges

  3. Department of Chemistry, School of Sciences, São Paulo State University, Bauru, SP, Brazil

    David Santos Souza Padovini & Aroldo Geraldo Magdalena

  4. Department of Mechanical Engineering, São Carlos School of Engineering, University of São Paulo, São Carlos, SP, Brazil

    Carlos Alberto Fortulan

  5. Department of Physics, School of Sciences, São Paulo State University, Bauru, SP, Brazil

    Paulo Noronha Lisboa-Filho

Authors
  1. Brunna Mota Ferrairo
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  2. Victor Mosquim
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  3. Lucas José de Azevedo-Silva
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Brunna Mota Ferrairo, Victor Mosquim, Lucas José de Azevedo-Silva, Luara Aline Pires and David Santos Souza Padovini. The first draft of the manuscript was written by Brunna Mota Ferrairo. The manuscript was revised by Aroldo Geraldo Magdalena, Carlos Alberto Fortulan, Paulo Noronha Lisboa-Filho, José Henrique Rubo and Ana Flávia Sanches Borges. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Ana Flávia Sanches Borges.

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Ferrairo, B.M., Mosquim, V., de Azevedo-Silva, L.J. et al. Experimental Silica-based Bioceramic Composite Added with Nano-sized Bovine Hydroxyapatite: Synthesis and Characterization. Silicon 15, 7171–7181 (2023). https://doi.org/10.1007/s12633-023-02563-8

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