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Diffusion and perfusion MRI parameters in the evaluation of placenta accreta spectrum disorders in patients with placenta previa

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Abstract

Objectives

To evaluate the placental function by monoexponential, biexponential, and diffusion kurtosis MR imaging (MRI) in patients with placenta previa.

Methods

A total of 62 patients with placenta accreta spectrum (PAS) disorders and 11 patients with normal placentas were retrospectively enrolled, who underwent conventional diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and diffusion kurtosis imaging (DKI). The apparent diffusion coefficient (ADC) and exponential ADC (eADC) from standard DWI, mean kurtosis (MK), and diffusion coefficient (MD) from DKI, and pure diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) from IVIM were measured and compared from the volumetric analysis.

Results

Comparisons between patients with PAS disorders and patients with normal placentas demonstrated that MD mean, D mean, and D* mean values in patients with PAS disorders were significantly higher than those in patients with normal placentas (p < 0.05). Comparisons between patients with accreta, increta, and percreta, and patients with normal placentas showed that the D mean was significantly higher in patients with placenta increta and percreta than in patients with normal placentas (p < 0.05).

Conclusion

The accreta lesions in PAS disorders had deceased cellularity and increased blood movement. The alteration of placental cellularity was more prominent in placenta increta and percreta.

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Funding

This research is supported by Sichuan Province Science and Technology Program (2021YJ0237).

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Authors and Affiliations

  1. Department of Radiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, 32 West Second Section, First Ring Road, Chengdu, 610072, China

    Tao Lu, Yishuang Wang, Yan Deng, Chengqian Wu & Xiangqi Li

  2. School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, 2006 Xiyuan Avenue, West Hi-tech Zone, Chengdu, 611731, China

    Guotai Wang

Authors
  1. Tao Lu
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  2. Yishuang Wang
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  3. Yan Deng
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  4. Chengqian Wu
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  5. Xiangqi Li
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  6. Guotai Wang
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Corresponding author

Correspondence to Guotai Wang.

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Ethical standards

The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013). This study was approved by the institutional review board of Sichuan Provincial People’s Hospital (approval number: 2021–282) and written informed consent was given by all participants.

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Lu, T., Wang, Y., Deng, Y. et al. Diffusion and perfusion MRI parameters in the evaluation of placenta accreta spectrum disorders in patients with placenta previa. Magn Reson Mater Phy 35, 1009–1020 (2022). https://doi.org/10.1007/s10334-022-01023-5

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  • DOI: https://doi.org/10.1007/s10334-022-01023-5

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