Abstract
Traditionally, endophytes are microorganisms that inhabit plant tissues, establishing an association with their hosts for most or all of their life without causing any apparent damage. Recently, researchers have shown an increased interest in the potential of endophytes to produce bio-active compounds with activity against numerous human, animal, and plant diseases. The determination of these bio-active molecules and their modes of action are technically challenging. Thus, the aim of this chapter is to provide a holistic point of view to the current strategies adopted for screening and production of novel endophyte-derived metabolites, such as terpenoids, alkaloids, phenylpropanoids, aliphatic compounds, polyketides, and peptides, and to present their commercial applications in the medicinal, pharmaceutical, agricultural food, and cosmetic industries.
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Filho, J.A.C. (2019). Production and Application of Novel Bio-active Compounds by Endophytic Microbes. In: Akhtar, M., Swamy, M., Sinniah, U. (eds) Natural Bio-active Compounds. Springer, Singapore. https://doi.org/10.1007/978-981-13-7154-7_1
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