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Activity-dependent regulation of the BAX/BCL-2 pathway protects cortical neurons from apoptotic death during early development Jonas SchroerDavide WarmAnne Sinning Original Article Open access 03 June 2023 Article: 175
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Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7 Eline J. H. van HoutumEsther D. Kers-RebelGosse J. Adema Original Article Open access 30 May 2023 Article: 169
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN Kaini ZhangChen YangDongming Su Original Article Open access 30 May 2023 Article: 168
Cell density-dependent membrane distribution of ganglioside GM3 in melanoma cells Motohide MurateNoriko YokoyamaToshihide Kobayashi Original Article 30 May 2023 Article: 167
Intestinal infection triggers mitochondria-mediated α-synuclein pathology: relevance to Parkinson’s disease João D. MagalhãesEmanuel CandeiasSandra Morais Cardoso Original Article 30 May 2023 Article: 166
G6PD activation in TNBC cells induces macrophage recruitment and M2 polarization to promote tumor progression Yin LiXiao HanChenggang Li Original Article 27 May 2023 Article: 165
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The summating potential polarity encodes the ear health condition Pierre Hakizimana Original Article Open access 24 May 2023 Article: 163
The role of blood flow in vessel remodeling and its regulatory mechanism during developmental angiogenesis Lin WenWenhua YanGuixue Wang Review 23 May 2023 Article: 162
Poly (ADP-ribose) polymerases 16 triggers pathological cardiac hypertrophy via activating IRE1α–sXBP1–GATA4 pathway Haibi SuJie XuYizhun Zhu Original Article Open access 23 May 2023 Article: 161
Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats Yueyang LiuXiaohang CheJingyu Yang Original Article 20 May 2023 Article: 160
Excessive iron inhibits insulin secretion via perturbing transcriptional regulation of SYT7 by OGG1 Xingqi ZhaoYing MaZhigang Guo Original Article 20 May 2023 Article: 159
Biased activation of the receptor tyrosine kinase HER2 Claudia CatapanoJohanna V. RahmMike Heilemann Original Article Open access 20 May 2023 Article: 158
Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response Quintin LeeRenhua SongJustin J.-L. Wong Original Article Open access 19 May 2023 Article: 157
CSNK1D-mediated phosphorylation of HNRNPA2B1 induces miR-25-3p/miR-93-5p maturation to promote prostate cancer cell proliferation and migration through m6A-dependent manner Feng QiWenyi ShenXiao Li Original Article 19 May 2023 Article: 156
Dietary intake of α-ketoglutarate ameliorates α-synuclein pathology in mouse models of Parkinson’s disease Wenlong ZhangLiuyan DingYunlong Zhang Original Article 19 May 2023 Article: 155
Tetraspanin Tspan8 restrains interferon signaling to stabilize intestinal epithelium by directing endocytosis of interferon receptor Jiang MinShenglan YangXin A. Zhang Original Article 19 May 2023 Article: 154
Serine-arginine protein kinases and their targets in viral infection and their inhibition Kai ZhengZhe RenYifei Wang Review 17 May 2023 Article: 153
BBOF1 is required for sperm motility and male fertility by stabilizing the flagellar axoneme in mice Huiwen CaoHaomang XuChao Yu Original Article 17 May 2023 Article: 152
The C-terminal 32-mer fragment of hemoglobin alpha is an amyloidogenic peptide with antimicrobial properties Lia-Raluca OlariRichard BauerJan Münch Original Article Open access 17 May 2023 Article: 151
Neurofilament accumulations in amyotrophic lateral sclerosis patients’ motor neurons impair axonal initial segment integrity Cynthia Lefebvre-OmarElise LiuDelphine Bohl Original Article Open access 15 May 2023 Article: 150
Development of VHL-recruiting STING PROTACs that suppress innate immunity Zhichuan ZhuRebecca L. JohnsonPengda Liu Original Article 14 May 2023 Article: 149
The pathogenesis of common Gjb2 mutations associated with human hereditary deafness in mice Qing LiChong CuiYilai Shu Original Article Open access 13 May 2023 Article: 148
Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma Dena PanovskaPouya NazariFrederik De Smet Original Article 12 May 2023 Article: 147
Correction: Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss Fuping QianGuanyun WeiDong Liu Correction 12 May 2023 Article: 146
Injury activated alveolar progenitors (IAAPs): the underdog of lung repair Lei ChongNegah AhmadvandJin-San Zhang Review Open access 11 May 2023 Article: 145
MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling Gang WangYulin LuoMao Luo Review 10 May 2023 Article: 144
Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components Caroline KampmeyerMartin Grønbæk-ThygesenRasmus Hartmann-Petersen Original Article Open access 09 May 2023 Article: 143
Darwin’s agential materials: evolutionary implications of multiscale competency in developmental biology Michael Levin Review Open access 08 May 2023 Article: 142
Proteomics analysis of prefrontal cortex of Alzheimer’s disease patients revealed dysregulated proteins in the disease and novel proteins associated with amyloid-β pathology Ana Montero-CalleRaquel CoronelRodrigo Barderas Original Article 07 May 2023 Article: 141
Neuronal progenitors of the dentate gyrus express the SARS-CoV-2 cell receptor during migration in the developing human hippocampus José Manuel Hernandez-LopezCristina Hernandez-MedinaSalvador Martinez Original Article Open access 07 May 2023 Article: 140
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