Articles

1. Modelling the Impact of NETosis During the Initial Stage of Systemic Lupus Erythematosus

   • Vladimira Suvandjieva
   • Ivanka Tsacheva
   • Peter Rashkov

   Original Article Open access 28 April 2024 Article: 66

   

2. Convex Representation of Metabolic Networks with Michaelis–Menten Kinetics

   • Josh A. Taylor
   • Alain Rapaport
   • Denis Dochain

   Original Article Open access 26 April 2024 Article: 65

   

3. A Genuinely Hybrid, Multiscale 3D Cancer Invasion and Metastasis Modelling Framework

   • Dimitrios Katsaounis
   • Nicholas Harbour
   • Nikolaos Sfakianakis

   Original Article Open access 25 April 2024 Article: 64

   

4. Modelling Plasmid-Mediated Horizontal Gene Transfer in Biofilms

   • Julien Vincent
   • Alberto Tenore
   • Luigi Frunzo

   Original Article Open access 25 April 2024 Article: 63

   

5. Coevolution of Age-Structured Tolerance and Virulence

   • Lydia J. Buckingham
   • Ben Ashby

   Original Article Open access 25 April 2024 Article: 62

   

6. A Mathematical Model for the Impact of 3HP and Social Programme Implementation on the Incidence and Mortality of Tuberculosis: Study in Brazil

   • Erick Manuel Delgado Moya
   • Jose Alejandro Ordoñez
   • Davide Rasella

   Original Article 25 April 2024 Article: 61

   

7. Untangling the Molecular Interactions Underlying Intracellular Phase Separation Using Combined Global Sensitivity Analyses

   • Kelsey I. Gasior
   • Nicholas G. Cogan

   Original Article Open access 20 April 2024 Article: 60

   

8. Bounds on the Ultrasensitivity of Biochemical Reaction Cascades

   • Marcello Pajoh-Casco
   • Abishek Vinujudson
   • German Enciso

   Original Article 18 April 2024 Article: 59

   

9. Integrating Diversity, Equity, and Inclusion into Preclinical, Clinical, and Public Health Mathematical Models

   • Justin Sheen
   • Lee Curtin
   • Morgan Craig

   Perspectives Open access 16 April 2024 Article: 56

10. Minimal Mechanisms of Microtubule Length Regulation in Living Cells

    • Anna C. Nelson
    • Melissa M. Rolls
    • Scott A. McKinley

    Original Article 16 April 2024 Article: 58

    

11. A Mathematical Model of TCR-T Cell Therapy for Cervical Cancer

    • Zuping Wang
    • Heyrim Cho
    • Noriko Sato

    Original Article 16 April 2024 Article: 57

    

12. Understanding and Quantifying Network Robustness to Stochastic Inputs

    • Hwai-Ray Tung
    • Sean D. Lawley

    Original Article 12 April 2024 Article: 55

    

13. Mathematical Modelling of Parasite Dynamics: A Stochastic Simulation-Based Approach and Parameter Estimation via Modified Sequential-Type Approximate Bayesian Computation

    • Clement Twumasi
    • Joanne Cable
    • Andrey Pepelyshev

    Methods Open access 10 April 2024 Article: 54

    

14. Mathematical Models of Early Hepatitis B Virus Dynamics in Humanized Mice

    • Stanca M. Ciupe
    • Harel Dahari
    • Alexander Ploss

    Original Article Open access 09 April 2024 Article: 53

    

15. Advice to a Young Mathematical Biologist

    • Paul A. Roberts

    Perspectives Open access 09 April 2024 Article: 52

16. Optimal Rotation Age in Fast Growing Plantations: A Dynamical Optimization Problem

    • Alex Altamirano-Fernández
    • Alejandro Rojas-Palma
    • Sergio Espinoza-Meza

    Original Article 06 April 2024 Article: 51

    

17. Dynamics of Information Flow and Task Allocation of Social Insect Colonies: Impacts of Spatial Interactions and Task Switching

    • Jun Chen
    • Xiaohui Guo
    • Yun Kang

    Original Article 06 April 2024 Article: 50

    

18. Artificial Neural Network Prediction of COVID-19 Daily Infection Count

    • Ning Jiang
    • Charles Kolozsvary
    • Yao Li

    Original Article 01 April 2024 Article: 49

    

19. Combinatorial Cooperativity in miR200-Zeb Feedback Network can Control Epithelial–Mesenchymal Transition

    • Mubasher Rashid
    • Brasanna M. Devi
    • Malay Banerjee

    Original Article 30 March 2024 Article: 48

    

20. Second-Order Effects of Chemotherapy Pharmacodynamics and Pharmacokinetics on Tumor Regression and Cachexia

    • Luke Pierik
    • Patricia McDonald
    • Jeffrey West

    Original Article 28 March 2024 Article: 47

    

21. Inferring Parameters of Pyramidal Neuron Excitability in Mouse Models of Alzheimer’s Disease Using Biophysical Modeling and Deep Learning

    • Soheil Saghafi
    • Timothy Rumbell
    • Casey O. Diekman

    Original Article Open access 25 March 2024 Article: 46

    

22. Enumeration of Rooted Binary Unlabeled Galled Trees

    • Lily Agranat-Tamir
    • Shaili Mathur
    • Noah A. Rosenberg

    Original Article Open access 22 March 2024 Article: 45

    

23. NIAID/SMB Workshop on Multiscale Modeling of Infectious and Immune-Mediated Diseases

    • Reed S. Shabman
    • Morgan Craig
    • Liliana L. Brown

    Perspectives Open access 21 March 2024 Article: 44

24. Impact of Resistance on Therapeutic Design: A Moran Model of Cancer Growth

    • Mason S. Lacy
    • Adrianne L. Jenner

    Original Article Open access 19 March 2024 Article: 43

    

25. Modeling of Mouse Experiments Suggests that Optimal Anti-Hormonal Treatment for Breast Cancer is Diet-Dependent

    • Tuğba Akman
    • Lisa M. Arendt
    • Alvaro Köhn-Luque

    Original Article Open access 18 March 2024 Article: 42

    

26. Nonlinear Regression Modelling: A Primer with Applications and Caveats

    • Timothy E. O’Brien
    • Jack W. Silcox

    Education Open access 15 March 2024 Article: 40

    

27. \(R_0\) May Not Tell Us Everything: Transient Disease Dynamics of Some SIR Models Over Patchy Environments

    • Ao Li
    • Xingfu Zou

    Original Article 15 March 2024 Article: 41

    

28. Discretised Flux Balance Analysis for Reaction–Diffusion Simulation of Single-Cell Metabolism

    • Yin Hoon Chew
    • Fabian Spill

    Methods Open access 06 March 2024 Article: 39

    

29. A Mathematical Model of Stroma-Supported Allometric Tumor Growth

    • Rachel Leander
    • Greg Owanga
    • Yeqian Liu

    Original Article 06 March 2024 Article: 38

    

30. Modelling the Effects of Growth and Remodelling on the Density and Structure of Cancellous Bone

    • Brianna L. Martin
    • Karen J. Reynolds
    • Murk J. Bottema

    Original Article Open access 04 March 2024 Article: 37

    

31. Parameter Identifiability in PDE Models of Fluorescence Recovery After Photobleaching

    • Maria-Veronica Ciocanel
    • Lee Ding
    • Björn Sandstede

    Original Article 02 March 2024 Article: 36

    

32. Correction to: Predicting Radiotherapy Patient Outcomes with Real-Time Clinical Data Using Mathematical Modelling

    • Alexander P. Browning
    • Thomas D. Lewin
    • Heiko Enderling

    Correction Open access 28 February 2024 Article: 35

33. First Passage Times of Long Transient Dynamics in Ecology

    • Grant R. Poulsen
    • Claire E. Plunkett
    • Jody R. Reimer

    Original Article 23 February 2024 Article: 34

    

34. 3D Genome Reconstruction from Partially Phased Hi-C Data

    • Diego Cifuentes
    • Jan Draisma
    • Kaie Kubjas

    Original Article Open access 22 February 2024 Article: 33

    

35. Order-of-Mutation Effects on Cancer Progression: Models for Myeloproliferative Neoplasm

    • Yue Wang
    • Blerta Shtylla
    • Tom Chou

    Original Article Open access 16 February 2024 Article: 32

    

36. Impacts of Vaccination and Severe Acute Respiratory Syndrome Coronavirus 2 Variants Alpha and Delta on Coronavirus Disease 2019 Transmission Dynamics in Four Metropolitan Areas of the United States

    • Abhishek Mallela
    • Ye Chen
    • William S. Hlavacek

    Original Article 14 February 2024 Article: 31

    

37. A Model for Membrane Degradation Using a Gelatin Invadopodia Assay

    • Giorgia Ciavolella
    • Nathalie Ferrand
    • Roberto Natalini

    Original Article 12 February 2024 Article: 30

    

38. Optimal Control with RdCVFL for Degenerating Photoreceptors

    • Kathryn Wifvat
    • Erika T. Camacho
    • Stephen Wirkus

    Original Article Open access 12 February 2024 Article: 29

    

39. Distinguishing Between Long-Transient and Asymptotic States in a Biological Aggregation Model

    • Jonathan R. Potts
    • Kevin J. Painter

    Original Article Open access 11 February 2024 Article: 28

    

40. Infectious Disease in the Workplace: Quantifying Uncertainty in Transmission

    • Jonathan I. D. Hamley
    • Guido Beldi
    • Daniel Sánchez-Taltavull

    Original Article Open access 01 February 2024 Article: 27

    

41. A Generalized Kinetic Model of Fractional Order Transport Dynamics with Transit Time Heterogeneity in Microvascular Space

    • Stefan Hindel

    Original Article 01 February 2024 Article: 26

    

42. Lyme Disease Models of Tick-Mouse Dynamics with Seasonal Variation in Births, Deaths, and Tick Feeding

    • Kateryna Husar
    • Dana C. Pittman
    • Linda J. S. Allen

    Original Article 31 January 2024 Article: 25

    

43. Ranked Subtree Prune and Regraft

    • Lena Collienne
    • Chris Whidden
    • Alex Gavryushkin

    Original Article Open access 31 January 2024 Article: 24

    

44. Making Your Own Luck: Weak Vertical Swimming Improves Dispersal Success for Coastal Marine Larvae

    • Alexander D. Meyer
    • Alan Hastings
    • John L. Largier

    Original Article Open access 28 January 2024 Article: 23

    

45. A Kinetic Finite Volume Discretization of the Multidimensional PIDE Model for Gene Regulatory Networks

    • Mihály A. Vághy
    • Irene Otero-Muras
    • Gábor Szederkényi

    Original Article Open access 22 January 2024 Article: 22

    

46. Turing Instabilities are Not Enough to Ensure Pattern Formation

    • Andrew L. Krause
    • Eamonn A. Gaffney
    • Benjamin J. Walker

    Original Article Open access 22 January 2024 Article: 21

    

47. Understanding the Interplay of CAR-NK Cells and Triple-Negative Breast Cancer: Insights from Computational Modeling

    • Abazar Arabameri
    • Samaneh Arab

    Original Article 19 January 2024 Article: 20

    

48. Predicting Radiotherapy Patient Outcomes with Real-Time Clinical Data Using Mathematical Modelling

    • Alexander P. Browning
    • Thomas D. Lewin
    • Heiko Enderling

    Original Article Open access 18 January 2024 Article: 19

    

49. A Countable-Type Branching Process Model for the Tug-of-War Cancer Cell Dynamics

    • Ren-Yi Wang
    • Marek Kimmel

    Original Article 18 January 2024 Article: 18

    

50. Sexual Dimorphism in Substrate Metabolism During Exercise

    • Stéphanie M. C. Abo
    • Elisa Casella
    • Anita T. Layton

    Original Article 16 January 2024 Article: 17