Volume 25, Issue 1 supplement

Search all Cardiovascular Drugs and Therapy articles

December 2011

An Arginine-Vasopressin V2 receptor Antagonist, Tolvaptan, for Treatment of Heart Failure with Volume Overload - Evidence from Nonclinical Studies to Clinical Trials

Issue Editor:

Masatsugu Hori

11 articles in this issue

Tolvaptan for Heart Failure Patients with Volume Overload
Masatsugu Hori
EditorialNotes 03 May 2011 Pages: 1 - 4
Pharmacokinetics, Pharmacodynamics and Safety of Tolvaptan, A Novel, Oral, Selective Nonpeptide AVP V₂-receptor Antagonist: Results of Single- and Multiple-Dose Studies in Healthy Japanese Male Volunteers
Seong Ryul Kim
Tomoko Hasunuma
Junichi Azuma
OriginalPaper 26 November 2011 Pages: 5 - 17
Effects of Tolvaptan on Volume Overload in Japanese Patients with Heart Failure: Results of a Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study
Masunori Matsuzaki
Masatsugu Hori
for the Tolvaptan Investigators
OriginalPaper 26 November 2011 Pages: 19 - 31
Efficacy and Safety of Tolvaptan in Heart Failure Patients with Volume Overload Despite the Standard Treatment with Conventional Diuretics: A Phase III, Randomized, Double-blind, Placebo-controlled Study (QUEST Study)
Masunori Matsuzaki
Masatsugu Hori
for the Tolvaptan Investigators
OriginalPaper 26 November 2011 Pages: 33 - 45
Efficacy and Safety of Tolvaptan in Heart Failure Patients with Sustained Volume Overload despite the Use of Conventional Diuretics: A Phase III Open-Label Study
Masatake Fukunami
Masunori Matsuzaki
for the Tolvaptan Investigators
OriginalPaper 26 November 2011 Pages: 47 - 56
Phase III Clinical Pharmacology Study of Tolvaptan
Takayuki Inomata
Tohru Izumi
for the Tolvaptan Investigators
OriginalPaper 26 November 2011 Pages: 57 - 65
Effects of Tolvaptan on Systemic and Renal Hemodynamic Function in Dogs with Congestive Heart Failure
Toshiyuki Onogawa
Yuki Sakamoto
Yoshitaka Yamamura
OriginalPaper 26 November 2011 Pages: 67 - 76
Anti-edematous Effects of Tolvaptan in Experimental Rodent Models
Toshiki Miyazaki
Yuki Sakamoto
Hiroyuki Fujiki
OriginalPaper 26 November 2011 Pages: 77 - 82
Nonclinical Pharmacokinetics of a New Nonpeptide V2 Receptor Antagonist, Tolvaptan
Masayuki Furukawa
Ken Umehara
Eiji Kashiyama
OriginalPaper 26 November 2011 Pages: 83 - 89
Nonclinical Safety Profile of Tolvaptan
Akihide Oi
Katsumi Morishita
Norio Ito
OriginalPaper 26 November 2011 Pages: 91 - 99
Erratum to: Tolvaptan for Heart Failure Patients with Volume Overload
Masatsugu Hori
Erratum 26 November 2011 Pages: 101 - 101

Volume 25, Issue 1 supplement

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