Zusammenfassung
Hintergrund
Das Dumping-Syndrom ist ein häufiges Phänomen nach Chirurgie des oberen Gastrointestinaltrakts. Die Bandbreite der Symptome umfasst milde gastrointestinale Beschwerden, über moderate vasomotorische Störungen bis hin zu schweren hyperinsulinämen Hypoglykämien. Durch die weltweit stetig steigende Zahl bariatrischer Operationen ist die bariatrische Chirurgie mittlerweile der häufigste Grund dieser Krankheitsentität.
Zielsetzung
In diesem Review soll die vorhandene Datenlage zum Dumping-Syndrom nach bariatrischer Chirurgie – insbesondere nach Roux-en-Y-Magenbypass und Magenschlauchbildung (Sleeve) – unter besonderer Berücksichtigung der dafür spezifischen Pathophysiologie, etwaiger Vermeidungsstrategien im Sinne operationstaktischer Überlegungen und Patientenselektion, Differenzialdiagnose und gradueller Diagnostik sowie möglicher Therapieoptionen dargestellt und diskutiert werden.
Abstract
Background
Dumping syndrome is a common complication after surgery of the upper gastrointestinal tract with symptoms ranging from mild gastrointestinal discomfort and moderate vasomotor disturbances, to severe hyperinsulinemic hypoglycemia. Due to the increasing number of bariatric procedures being performed worldwide, bariatric surgery has become the most common cause for this disease entity.
Objective
The aim of this review is to highlight the evidence for the physiological mechanisms contributing to dumping syndrome after the two most common bariatric surgery procedures, Roux-en-Y gastric bypass and sleeve gastrectomy, to discuss technical aspects of the procedures underlying the development of the syndrome, patient-related predictive factors and other differential diagnoses, together with diagnostic and therapeutic algorithms.
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F. Seyfried, A. Wierlemann, M. Bala, M. Fassnacht und C. Jurowich geben an, dass kein Interessenkonflikt besteht.
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Seyfried, F., Wierlemann, A., Bala, M. et al. Dumping-Syndrom. Chirurg 86, 847–854 (2015). https://doi.org/10.1007/s00104-015-0047-3
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DOI: https://doi.org/10.1007/s00104-015-0047-3