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Time-Resolved MRI After Ingestion of Liquids Reveals Motility Changes After Laparoscopic Sleeve Gastrectomy—Preliminary Results

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Abstract

Background

Laparoscopic sleeve gastrectomy (LSG) is generally considered a restrictive procedure. However, studies with nuclear medicine techniques have demonstrated that gastric motility changes occur following LSG. These motility changes could represent complementary mechanisms of weight loss. Therefore, we analyzed the stomach motility before and after LSG by means of dynamic MRI.

Methods

In this prospective pilot study, five female patients with a mean BMI of 51.6 kg/m2 underwent MRI 1 day before LSG and 6 days and 6 months after LSG. Dynamic steady-state free precession sequences were used to analyze the gastric motility after ingestion of 500 ml water with a temporal resolution of 0.86 s. Axial image stacks were also repeatedly acquired to determine the intragastric fluid volume over time.

Results

Mean excess body mass index loss was 60.6% after 6 months. Dynamic analysis showed that antral propulsive peristalsis was preserved immediately after surgery and during follow-up, but fold speed increased significantly from 2.7 mm/s before LSG to 4.4 mm/s after 6 months. The sleeve itself remained without recognizable peristalsis in three patients and showed only uncoordinated or passive motion in two patients. Consequently, the fluid transport through the sleeve was markedly delayed, whereas the antrum showed accelerated propulsion with the emptying half-time decreasing from 16.5 min preoperatively to 7.9 min 6 months after surgery.

Conclusions

Owing to the LSG procedure, the stomach is functionally divided into a sleeve without propulsive peristalsis and an accelerated antrum. Accelerated emptying seems to be caused by faster peristaltic folds.

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Conflicts of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Radiology, University Hospital Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany

    Tobias Baumann, Lisa Zimmermann, Arnd-Oliver Schaefer & Mathias Langer

  2. Department of General and Visceral Surgery, University Hospital Freiburg, Freiburg, Germany

    Simon Kuesters, Jodok Grueneberger, Goran Marjanovic, Ulrich Theodor Hopt & Wojciech Konrad Karcz

Authors
  1. Tobias Baumann
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  2. Simon Kuesters
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  3. Jodok Grueneberger
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  4. Goran Marjanovic
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  5. Lisa Zimmermann
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  6. Arnd-Oliver Schaefer
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  7. Ulrich Theodor Hopt
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  8. Mathias Langer
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  9. Wojciech Konrad Karcz
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Corresponding author

Correspondence to Tobias Baumann.

Additional information

T. Baumann and S. Kuesters contributed equally to this work.

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Baumann, T., Kuesters, S., Grueneberger, J. et al. Time-Resolved MRI After Ingestion of Liquids Reveals Motility Changes After Laparoscopic Sleeve Gastrectomy—Preliminary Results. OBES SURG 21, 95–101 (2011). https://doi.org/10.1007/s11695-010-0317-6

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  • DOI: https://doi.org/10.1007/s11695-010-0317-6

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