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Meningioma

  • Chapter
Radiotherapy for Non-Malignant Disorders

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Most meningiomas are histologically benign and typically slow-growing lesions arising from the arachnoidal cap cells. They often occur in the arachnoidal granulations area next to the venous sinus. Meningiomas cause symptoms by extraaxial compression of the adjacent brain. The treatment of choice is surgical resection. Most meningiomas can be completely resected, but they have a high tendency for local recurrence, especially after subtotal surgical intervention. After complete resection, long-term disease-free survival can be achieved in 81% of the patients, with local tumor control of 96%. Relapses occurred from 4 to 17 years after the initial surgery intervention. Recurrence rates for patients after subtotal resection range from 17% to 100%. Radiation therapy after subtotal resection can achieve results comparable to those of complete resection [40].

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Authors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany

    Stefanie Milker-Zabel MD & Jürgen Debus MD (Professor)

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  1. Stefanie Milker-Zabel MD
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  2. Jürgen Debus MD
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Editors and Affiliations

  1. Department of Radiation Oncology and Therapeutic Radiology, Alfried-Krupp-Hospital, Alfried-Krupp-Strasse 21, Postfach 10 22 43, 45117, Essen, Germany

    Michael Heinrich Seegenschmiedt MD (Professor) (Professor)

  2. Strahlenklinik Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany

    Hans-Bruno Makoski MD (Professor) (Professor)

  3. Department of Radiation Biology, St. Bartolomew’s Medical College, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott MD (Professor) (Professor)

  4. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

  5. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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Milker-Zabel, S., Debus, J. (2008). Meningioma. In: Seegenschmiedt, M.H., Makoski, HB., Trott, KR., Brady, L.W. (eds) Radiotherapy for Non-Malignant Disorders. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68943-0_35

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