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Sister Chromatid Exchanges and Mitotic Crossing-Over

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Human Chromosomes

Part of the book series: Springer Study Edition ((SSE))

Abstract

Sister chromatid exchanges (SCEs) were discovered in the late 1950s with the same type of experiment as demonstrated the semiconservative replication of chromosomes (Chapter 3). When cells are grown for one cycle in medium containing [3H]thymidine and for another without it, autoradiography shows that one chromatid is labeled and the other is not (Figs. 3.2 and 3); this makes exchanges between them visible (Taylor, 1958).

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Author information

Authors and Affiliations

  1. Department of Medical Genetics, University of Wisconsin, Madison, WI, 53706, USA

    Eeva Therman

  2. Medical School, University of Wisconsin, Madison, WI, 53706, USA

    Millard Susman

Authors
  1. Eeva Therman
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  2. Millard Susman
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© 1993 Springer-Verlag New York, Inc.

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Therman, E., Susman, M. (1993). Sister Chromatid Exchanges and Mitotic Crossing-Over. In: Human Chromosomes. Springer Study Edition. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0529-3_12

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  • DOI: https://doi.org/10.1007/978-1-4684-0529-3_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-97871-0

  • Online ISBN: 978-1-4684-0529-3

  • eBook Packages: Springer Book Archive

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