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The Clinical Pharmacology of Potassium Channels

  • Chapter
Ion Channels and Ion Pumps

Part of the book series: Endocrinology and Metabolism ((EAM,volume 6))

Abstract

Potassium channels form a remarkably diverse group of ion channel structures.1 More subtypes of potassium channels, with different biophysical and/or pharmacologic properties, are known than of any other type of ion channel. One of the most important roles of these channels is the regulation of membrane potential and excitability in nerve and muscle cells. Many potassium channels in turn are regulated by second messengers and other molecules of intermediary metabolism, such as G proteins, cAMP, ATP, inositol trisphosphate, and calcium.2 In this manner potassium channels provide an important link between membrane potential and cell metabolism.

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  1. P. N. Strong
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Editors and Affiliations

  1. 48323, 2104 Rhine Road, West Bloomfield, MI, USA

    Piero P. Foà M.D., Sc.D. (Professor Emeritus) (Professor Emeritus)

  2. Department of Physiology, Wayne State University, 48202, Detroit, MI, USA

    Piero P. Foà M.D., Sc.D. (Professor Emeritus) (Professor Emeritus)

  3. Section of Endocrinology,Department of Internal Medicine,School of Medicine, Wayne State University, 48202, Detroit, MI, USA

    Mary F. Walsh Ph.D. (Assistant Professor) (Assistant Professor)

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© 1994 Springer-Verlag New York, Inc.

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Strong, P.N. (1994). The Clinical Pharmacology of Potassium Channels. In: Foà, P.P., Walsh, M.F. (eds) Ion Channels and Ion Pumps. Endocrinology and Metabolism, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2596-6_17

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  • DOI: https://doi.org/10.1007/978-1-4612-2596-6_17

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7599-2

  • Online ISBN: 978-1-4612-2596-6

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