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Probiotic Bacteria and Enteric Infections

Cytoprotection by Probiotic Bacteria

  • Book
  • © 2011

Overview

  • Describes the possible mechanisms of action of probiotics that are not described by available books
  • Describes the probiotic–omics that are not described by any other book
  • Discusses on genetic engineering and designer probiotics that are not discussed in other books
  • Explains in details the benefits of probiotics and the recommended regime for their application in disease treatment
  • Presents recent data on immunological interference by probiotic bacteria
  • Includes supplementary material: sn.pub/extras

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Table of contents (19 chapters)

  1. Introduction and History of Probiotics

  2. The Gut Microorganisms and Probiotics

  3. Pathophysiology of Enteric Disorders Due to Disturbed Microbiota

  4. Application of Molecular Biology and -omics of Probiotics in Enteric Protection

  5. Probiotics, Gut Immunology and Enteric Protection

  6. Probiotics for Enteric Therapy

Keywords

About this book

Every day many people suffer from intestinal diseases. These disorders can result from pathogens like bacteria, fungi, parasites and viruses, but the causes of non-infectious intestinal disorders and colorectal cancers remain to be elucidated. Disturbances to the normal gut flora (the microbiota) are central to the development of many, if not all, of these disorders.  

Disturbed gut microbiota is a prelude to public health issues like traveller’s-, antibiotic- and Clostridium difficile-associated diarrhoea, irritable bowel syndrome, inflammatory bowel disease, and colorectal cancers.  This book discusses the way intestinal disorders affect the microbiota, how the disturbed microbiotal balance leads to enteric disorders and the ways to prevent these disorders.

Further his book explores the potential of probiotics (live microorganisms that when ingested bring a health benefit) in treating enteric disorders by analysing the probiotic genome through proteomics, metabolomics and functional assays. Discussed is how the ingestion of specific microorganisms repairs the disturbed microbiota and subsequently ameliorates enteric disorders. Finally this book addresses how genetic engineering and biotechnology will contribute to the development of effective and safe designer probiotics.

Editors and Affiliations

  • Faculty of Veterinary Medicine, Department of Veterinary Pathology, Sokoine University of Agriculture, Chuo Kikuu, Morogoro, Tanzania

    J.J. Malago

  • Division Pathology, Dept of Pathobiology, Utrecht University, Utrecht, Netherlands

    J.F.J.G. Koninkx

  • Biotechnical Faculty, Zootechnical Department, University of Ljubljana, Domžale, Slovenia

    R. Marinsek-Logar

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