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Promoting Gut Health with Probiotic Metabolomics

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Abstract

Today metabolomic approaches are aiming at the quest for homeostatic balance which is dependent not only on the host but also on the crucial metabolic interactions with microbial symbionts. Indeed, metabolomics technologies are broadening our knowledge on the roles of the human gut microbiota and how they influence health and disease etiology. While the mechanisms of action of our gut symbionts are only now being unveiled, potential health benefits are being suggested by modulating the microbial functional ecology with the use of probiotics. This chapter discusses latest metabolomics applications to explore mammalian gut microbial metabolic interactions with key emphasis on deciphering bacterial role in maintaining host health balance, as well as preventing and treating metabolic disorders.

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Authors and Affiliations

  1. BioAnalytical Science, Metabolomics & Biomarkers, Nestlé Research Center, P.O. Box 44, 1000, Lausanne 26, Switzerland

    Sebastiano Collino, François-Pierre J. Martin, Sunil Kochhar & Serge Rezzi

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  1. Sebastiano Collino
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  2. François-Pierre J. Martin
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  3. Sunil Kochhar
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  4. Serge Rezzi
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Correspondence to Serge Rezzi .

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Editors and Affiliations

  1. Faculty of Veterinary Medicine, Department of Veterinary Pathology, Sokoine University of Agriculture, Chuo Kikuu, Morogoro, Tanzania

    J.J. Malago

  2. Division Pathology, Dept of Pathobiology, Utrecht University, Yalelaan 1, Utrecht, 3508 TD, Netherlands

    J.F.J.G. Koninkx

  3. Biotechnical Faculty, Zootechnical Department, University of Ljubljana, Domžale, 1230, Slovenia

    R. Marinsek-Logar

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Collino, S., Martin, FP.J., Kochhar, S., Rezzi, S. (2011). Promoting Gut Health with Probiotic Metabolomics. In: Malago, J., Koninkx, J., Marinsek-Logar, R. (eds) Probiotic Bacteria and Enteric Infections. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-0386-5_8

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