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Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates

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An Erratum to this article was published on 12 October 2017

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Abstract

The yeast Kluyveromyces lactis has received attention both from academia and industry due to some important features, such as its capacity to grow in lactose-based media, its safe status, its suitability for large-scale cultivation and for heterologous protein synthesis. It has also been considered as a model organism for genomics and metabolic regulation. Despite this, very few studies were carried out hitherto under strictly controlled conditions, such as those found in a chemostat. Here we report a set of quantitative physiological data generated during chemostat cultivations with the K. lactis CBS 2359 strain, obtained under glucose-limiting and fully aerobic conditions. This dataset serve as a basis for the comparison of K. lactis with the model yeast Saccharomyces cerevisiae in terms of their elemental compositions, as well as for future metabolic flux analysis and metabolic modelling studies with K. lactis.

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Change history

  • 12 October 2017

    In the original publication of the article, the below mentioned errors have appeared. The correct text is provided in this erratum, In the abstract section, the sentence “This dataset serve” should be replaced as “This dataset serves”. Also, the reference “Basso TO, Gomes FS, Lopes ML, et al (2014) Homo- and heterofermentative lactobacilli differently affect sugarcane-based fuel ethanol fermentation. Antonie Van Leeuwenhoek 105:169–177. doi: 10.1007/s10482-013-0063-6 ” should be replaced as “Basso TO, Dario MG, Tonso A, Stambuk BU, Gombert AK (2010) Insufficient uracil supply in fully aerobic chemostat cultures of Saccharomyces cerevisiae leads to respiro-fermentative metabolism and double nutrient-limitation. Biotechnol Lett 32:973–977. doi: 10.1007/s10529-010-0248-2 ”. Finally, in the Table 2 footnote, “according to (Heijnen 1981)” should be replaced as “according to Heijnen (1981)”.

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Acknowledgements

This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE-01-0145-FEDER-000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norte. T.O.B. would like to express his gratitude for funds provided by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, Brasília, Brazil).

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  1. Oscar Dias and Thiago O. Basso contributed equally to this work.

Authors and Affiliations

  1. Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal

    Oscar Dias, Isabel Rocha & Eugénio C. Ferreira

  2. Department of Chemical Engineering, Polytechnic School, University of São Paulo, Av. Prof. Luciano Gualberto 380, São Paulo, SP, 05508-010, Brazil

    Oscar Dias, Thiago O. Basso & Andreas K. Gombert

  3. School of Food Engineering, University of Campinas, Rua Monteiro Lobato 80, Campinas, SP, 13083-862, Brazil

    Andreas K. Gombert

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  1. Oscar Dias
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Correspondence to Thiago O. Basso.

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An erratum to this article is available at https://doi.org/10.1007/s10482-017-0948-x.

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Dias, O., Basso, T.O., Rocha, I. et al. Quantitative physiology and elemental composition of Kluyveromyces lactis CBS 2359 during growth on glucose at different specific growth rates. Antonie van Leeuwenhoek 111, 183–195 (2018). https://doi.org/10.1007/s10482-017-0940-5

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